Evidence from the field: Fractional doses of yellow fever vaccine provided protection, study finds
Health workers resorted to using fractional doses of yellow fever vaccine in the midst of an outbreak. The fractional doses seem to have worked.
A 2016 emergency yellow fever vaccination campaign that had to resort to using smaller than standard doses because of a global vaccine shortage appears to have protected the people who were vaccinated, a new study suggests.
People who received a fractional dose — one-fifth the standard size — showed strong immune responses a month after they received the single dose of vaccine, the authors reported in the New England Journal of Medicine.
While the study — conducted during a mass vaccination campaign in Kinshasa, capital of the Democratic Republic of Congo —
