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Coronavirus: U.S. Enters 'Quarantine Life' As Many Schools And Businesses Close

The United States is embarking on a new normal as widespread school closures and other measures to curb the spread of COVID-19 take effect.

Updated at 1:30 p.m. ET

The United States is entering its first week of widespread school closures and restrictions on restaurants, bars and other businesses, as the COVID-19 pandemic remakes daily life for millions of Americans.

People who work in service industries now face the prospect of weeks without pay, while others are working from home. Businesses are watching for ripple effects of unexpected slowdowns and cancellations — and hoping to weather what will likely be a prolonged disruption to normal life.

"This is the defining global health crisis of our time," World Health Organization Director-General Tedros Adhanom Ghebreyesus said Monday. The days, weeks and months ahead will be a test of our resolve, a test of our trust in science and a test of solidarity."

Tedros added, "Crises like COVID-19 tend to bring out the best and worst in humanity."

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