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    Lifespan: Why We Age—and Why We Don't Have To
    Lifespan: Why We Age—and Why We Don't Have To
    Lifespan: Why We Age—and Why We Don't Have To
    Audiobook11 hours

    Lifespan: Why We Age—and Why We Don't Have To

    Written by David A. Sinclair and Matthew D. LaPlante

    Narrated by David A. Sinclair

    4.5/5

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    About this audiobook

    Audio Bonus! Includes exclusive conversations with the authors!

    A NEW YORK TIMES BESTSELLER
    “Brilliant and enthralling.”​ —The Wall Street Journal

    A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people.

    It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan?

    In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.”

    This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger.

    Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.
    LanguageEnglish
    PublisherSimon & Schuster Audio
    Release dateSep 10, 2019
    ISBN9781508296058
    Author

    David A. Sinclair

    David Sinclair, PhD, AO, is a professor of genetics at Harvard Medical School. One of the leading innovators of his generation, he has been named by Time as “one of the 100 most influential people in the world” and top fifty most influential people in healthcare. He is a board member of the American Federation for Aging Research and has received more than thirty-five awards for his research and major scientific breakthroughs. Dr. Sinclair and his work have been featured on 60 Minutes, Today, The Wall Street Journal, The New York Times, Fortune, and Newsweek, among others. To learn more, visit LifespanBook.com and follow him on Twitter @DavidASinclair.

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    Reviews for Lifespan

    4.5/5

    436 ratings29 reviews

    What did you think?

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    Review must be at least 10 words

    • 5/5
      In Lifespan, Professor Sinclair presents the Information Theory of Aging and provides ample evidence to support his theory. If his current techniques work as well in humans as they do in model organisms, we will see a step function change in medicine. This should extend the healthy lifespan of human beings and save the economy trillions of dollars. David Sinclair is a tenured professor at Harvard Medical School.

      2 people found this helpful

    • 5/5
      The best and relevant book of aging and its technologies without any further questions

      1 person found this helpful

    • 5/5
      Exceptional information on the state of longevity with a positive outlook on humanity.

      1 person found this helpful

    • 5/5
      Amazing listening over 2 days. Amazing narrative from the author itself ☺️

      1 person found this helpful

    • 5/5
      Such a great book! As a medical professional, a son, husband, and father , I truly appreciate the content here in. Thank you very much.

      1 person found this helpful

    • 5/5
      I like the insights regarding how will medicine be like 10-20 years from now, and how will it affect us. I learned a lot about the history and the events that shape us up to the present. He also foresee the pandemic which we all experiencing right now.

      1 person found this helpful

    • 5/5
      This is definitely worth a listen if you find David Sinclair's work even mildly interesting. The depth of research and information is excellently brought together to paint a really picture of what the future of aging and human health could look like. Along with this he discusses some very important questions about humanity, aging and the journey ahead. Thank you to all involved across this field of research. ?

      1 person found this helpful

    • 4/5
      As far as I know, Dr. Sinclair's take on anti-aging molecules and epigenetics are correct. I found the book very informative. He gets a little out of his expertise at the end, with some ridiculas claims about world politics, from a far leftist point of view, but otherwise a very good book.

      1 person found this helpful

    • 5/5
      Amazing to hear the research on human aging that has been happening behind the scenes for so many years.

      1 person found this helpful

    • 5/5
      An original and thought provoking book about the future of health research.

      1 person found this helpful

    • 5/5
      A fascinating look into the future of healthcare and medicine. As a genetics student who actually works in a lab for one of Sinclair's former students I was very interested in reading this. I very much enjoyed reading about his research and also his opinions about the ethics and future of this work. The book may be difficult for non science readers but I'd encourage you to do your own research into the things mentioned. I expect this book to increase in popularity and possibly fuel a change in the way we see our future as a species.

      1 person found this helpful

    • 5/5
      Quite scary, but very interesting. This book is not a self help one, instead it tries to show what has been done in order to see aging as a disease and how to slow it.

      1 person found this helpful

    • 5/5
      The writer is interestingly optimistic in a a not foolish way. He presented great findings in aging.

      1 person found this helpful

    • 5/5
      Highly informative and mind boggling book about the latest discoveries on ageing and human health in general.
    • 5/5
      Important. Well written. Well read. Thank you to the author.
    • 5/5
      Fascinating! Inspiring! Exciting! Loved it! I’m excited to learn more about the advances of aging, and live to the age of 150!
    • 4/5
      The last chapters were rather unnecessary, overly inspirational and repetitive and much less experimental support. It actually sounded more like a self help book than a pop science book for those chapters. Otherwise it was a good book.
    • 5/5
      Ich habe gehört die ganze Buch .Einfach wunderbar.Vilen Dank David ❤️
    • 5/5
      An eye opening book with research base data and incredible and understandable explanations. Made me think about family members and give then the understanding that aging is just a currable disease.
    • 5/5
      Great, bold and mind-opening book! Anybody can take o few thingsfrom the book and apply them in their life to improve the healthspan.
    • 5/5
      This is must read to understand the latest technology in aging, vitality and lifespan space. The first three quarters of the book was extremely engaging. The last quarter was about justification for the first part and it was repititive. Overall, I would urge everyone to read this book.
    • 5/5
      Great book! Definitely an eye opener! Check it out ?!
    • 5/5
      This book paints an amazing vision of the future. It starts with the science of longevity before meandering through the philosophical implications of longer human life. A powerful call to action that has already inspired me to make some lifestyle changes.
    • 5/5
      Just finished a 2nd listen a year later. Even better this time around and still completely relevant.
    • 5/5
      Wait, you make your own yogurt? What else aren’t you telling us?
      But seriously, this book was eye-opening. It really does deliver on its promise of a back-stage pass to a lot of great cutting-edge research into the big picture of human health, genetics, and aging. It is a great starting-point to really understanding what we can do (both now and in the near future) to increase our “healthspan.”
      I really appreciated the ethical and socio-political chapters at the end of the book. The author duo does a great job covering a LOT of good science and its implications.
      I actually finished the audiobook and then immediately re-read it because there were so many great details that I wanted to keep straight.
      Looking forward to following up on the outcome of this line of research for “many years to come.”
    • 5/5
      One of the most important books I’ve ever read. I highly recommend it to everyone I know and care about.
    • 5/5
      For informative, inspiring and fun to listen to. It’s defiantly worth listening to in my opinion.
    • 3/5
      I am not a scientist, as such I should not have opted for the audiobook. Print might have been a better choice. Too bad because the topic does interest me--I simply didn't understand anything.
      That said, a nice voice verbalizing incompréhensible words helped me fall asleep quickly for an entire week.

      3 people found this helpful

    • 5/5
      Words like powerful, moving, inspirational, and paradigm shifting, appropriate as they might be, fail to capture the true significance of this work to the human condition. I am at once profoundly optimistic and deeply troubled by the ramifications of Sinclair’s words and work. Like his fictional alien race of jurors, I’m not convinced we are ready as a species to accept this new paradigm, or that we even deserve it. And I have good reason to feel that way. I teach in an American public school, going on 12 years now, and while I have known dozens of bright, willing, eager, and grateful students, they are the minority. Blessed with the freedoms, advances, and opportunities that their ancestors could not have imagined, the majority of students today simply stare in dull apathy before bolting for the door and getting back on their cell phones, if they bother to wait until leaving the room. And a not insignificant minority actively work to degrade the system that has been established to keep us all from slipping back into medieval ignorance. And I work in a relatively affluent school district in a relatively affluent and educated part of the country-the Austin area of central Texas.
      I did not start this review with the intention of veering off into a critique of the American education system or its students, but that does show how thought provoking this book has been and will likely continue to be for many months and years to come. I think these, and the many potential issues Sinclair raises in his work, should be addressed before we go too far down this road. I am not convinced we are in a position to wisely shoulder the responsibility of the longevity he predicts. However, his arguments ring true, and despite my trepidation, I am eager to see his research, and that of other minds in his field, play out on the world stage. And I plan on sharing it with my middle school science students.

      3 people found this helpful