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    Wilson's Disease: Causes, Tests and Treatment Options
    Wilson's Disease: Causes, Tests and Treatment Options
    Wilson's Disease: Causes, Tests and Treatment Options
    Ebook61 pages34 minutes

    Wilson's Disease: Causes, Tests and Treatment Options

    By Janet Rena

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    About this ebook

    Copper or Cuprum is a trace mineral, considered to play a vital role in maintaining normal processes within the body. It is the structural component of many enzymes in our body systems, and is responsible in assisting iron to be utilized by the tissues. It also removes free radicals from the body and helps prevent damage in cell structures, making it a powerful antioxidant. These are just some of the many benefits we could get from copper.
    But what happens when this powerful mineral goes beyond the level of what is tolerated and needed by the body? It then becomes a problem --- from being an antioxidant, a free-radical fighter, it becomes a deadly poison, a threat to life. This is what happens in Wilson’s Disease.
    This must-have book outlines the causes, diagnostic tests and treatment options for the disease.

    LanguageEnglish
    PublisherAndale LLC
    Release dateMay 13, 2012
    ISBN9781476459189
    Wilson's Disease: Causes, Tests and Treatment Options

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      Book preview

      Wilson's Disease - Janet Rena

      Wilson’s Disease: Causes, Tests and Treatment Options

      Janet Rena, MA; Ernest Sutherland, MD

      Smashwords Edition

      ****

      Copyright 2012 Janet Rena, MA; Ernest Sutherland, MD

      Smashwords Edition, License Notes

      This ebook is licensed for your personal enjoyment only. This ebook may not be re-sold or given away to other people. If you would like to share this book with another person, please purchase an additional copy for each recipient. If you’re reading this book and did not purchase it, or it was not purchased for your use only, then please purchase your own copy. Thank you for respecting the hard work of this author.

      Contents

      Introduction

      Signs and Symptoms

      Preparing for your appointment

      Diagnosis

      Treatment

      Complications

      Prognosis

      Prevention

      Appendix A: Internet Resources / Further Reading

      Introduction

      Copper or Cuprum is a trace mineral, considered to play a vital role in maintaining normal processes within the body. It is the structural component of many enzymes in our body systems, and is responsible in assisting iron to be utilized by the tissues. It also removes free radicals from the body and helps prevent damage in cell structures, making it a powerful antioxidant. These are just some of the many benefits we could get from copper.

      But what happens when this powerful mineral goes beyond the level of what is tolerated and needed by the body? It then becomes a problem --- from being an antioxidant, a free-radical fighter, it becomes a deadly poison, a threat to life. This is what happens in Wilson’s Disease.

      Overview of the Disease

      Wilson’s Disease is a rare genetic disorder which impairs the excretion of copper out of the body. It was described in the early 1900s by Alexander Kinnier Wilson, the British Neurologist, who was working at England during that time. Since there is the accumulation of copper in the body due to the faulty metabolism, damages to vital organs occur specifically in the liver, the brain, and the eyes, and may also run further to other organs affecting several functions, causing damage to the body as a whole. The condition is also termed as copper storage disease or hepatolenticular degeneration.

      What Causes Wilson’s Disease?

      Wilson’s Disease rarely happens. If it does, it could be due to the abnormal changes in the ATP7B gene, a gene inherited as an autosomal recessive trait. The ATP7B gene is located in chromosome 13, and its function in the metabolism is to regulate a protein responsible for copper transport (copper-transporting ATPase). The moving of copper out of the body is done by incorporating the mineral into ceruloplasmin. If both parents have that WD gene, there is a chance of transferring the condition to offspring in each pregnancy of 25%.

      Who is at Risk?

      Wilson’s Disease affects

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