Unavailable
Unavailable
Unavailable
Ebook3,579 pages42 hours
Handbook of Pharmacogenomics and Stratified Medicine
Rating: 0 out of 5 stars
()
Currently unavailable
Currently unavailable
About this ebook
Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be accessible to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by pharmacogenomics and stratified medicine details.
Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development.
Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development.
- Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise
- Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics, pharmacokinetics and pharmacodynamics
- Covers newer technologies– next generation sequencing, proteomics, metabolomics
- Provides information on animal models, lymphoblastoid cell lines, stem cells
- Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues
- Includes chapters on the global implications of pharmacogenomics
Unavailable
Related to Handbook of Pharmacogenomics and Stratified Medicine
Related ebooks
Global Clinical Trials for Alzheimer's Disease: Design, Implementation, and Standardization Rating: 0 out of 5 stars0 ratingsGenetic Diagnosis of Endocrine Disorders Rating: 0 out of 5 stars0 ratingsA Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery Rating: 1 out of 5 stars1/5Atkinson's Principles of Clinical Pharmacology Rating: 0 out of 5 stars0 ratingsHistone Modifications in Therapy Rating: 0 out of 5 stars0 ratingsPharmaceutics: Basic Principles and Application to Pharmacy Practice Rating: 0 out of 5 stars0 ratingsProgress in Genomic Medicine: From Research to Clinical Application Rating: 0 out of 5 stars0 ratingsPrinciples of Clinical Pharmacology Rating: 3 out of 5 stars3/5Applied Genomics and Public Health Rating: 0 out of 5 stars0 ratingsBiomarkers in Inborn Errors of Metabolism: Clinical Aspects and Laboratory Determination Rating: 5 out of 5 stars5/5Pharmaceutical Medicine and Translational Clinical Research Rating: 0 out of 5 stars0 ratingsAntibiotics: Origin, Nature and Properties Rating: 0 out of 5 stars0 ratingsFrontiers in Clinical Drug Research - Anti Infectives: Volume 2 Rating: 0 out of 5 stars0 ratingsPharmacokinetics: A Tutorial Study Guide Rating: 2 out of 5 stars2/5Vaccines for Cancer Immunotherapy: An Evidence-Based Review on Current Status and Future Perspectives Rating: 0 out of 5 stars0 ratingsEmery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Perinatal and Reproductive Genetics Rating: 0 out of 5 stars0 ratingsAntimicrobial Drug Resistance Rating: 0 out of 5 stars0 ratingsNanotechnology-Based Targeted Drug Delivery Systems for Lung Cancer Rating: 0 out of 5 stars0 ratingsA Comprehensive Guide to Toxicology in Preclinical Drug Development Rating: 5 out of 5 stars5/5Frontiers in Computational Chemistry: Volume 5 Rating: 0 out of 5 stars0 ratingsAn Introduction to Pharmacology: A Tutorial Study Guide Rating: 3 out of 5 stars3/5Revising basic and clinical pharmacology: eBook Rating: 0 out of 5 stars0 ratingsPrinciples of Translational Science in Medicine: From Bench to Bedside Rating: 0 out of 5 stars0 ratingsHormones, Lipoproteins and Atherosclerosis: Advances in Physiological Sciences Rating: 0 out of 5 stars0 ratingsTarget Validation in Drug Discovery Rating: 0 out of 5 stars0 ratingsA History of Immunology Rating: 0 out of 5 stars0 ratingsPharmacy Practice Research Case Studies Rating: 5 out of 5 stars5/5Precision Medicine for Investigators, Practitioners and Providers Rating: 0 out of 5 stars0 ratingsNanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors Rating: 0 out of 5 stars0 ratings
Biology For You
The Winner Effect: The Neuroscience of Success and Failure Rating: 5 out of 5 stars5/5"Cause Unknown": The Epidemic of Sudden Deaths in 2021 & 2022 Rating: 5 out of 5 stars5/5The Soul of an Octopus: A Surprising Exploration into the Wonder of Consciousness Rating: 4 out of 5 stars4/5Gut: The Inside Story of Our Body's Most Underrated Organ (Revised Edition) Rating: 4 out of 5 stars4/5Sapiens: A Brief History of Humankind Rating: 4 out of 5 stars4/5Why We Sleep: Unlocking the Power of Sleep and Dreams Rating: 4 out of 5 stars4/5The Grieving Brain: The Surprising Science of How We Learn from Love and Loss Rating: 4 out of 5 stars4/5A Letter to Liberals: Censorship and COVID: An Attack on Science and American Ideals Rating: 3 out of 5 stars3/5Mother of God: An Extraordinary Journey into the Uncharted Tributaries of the Western Amazon Rating: 4 out of 5 stars4/5The Sixth Extinction: An Unnatural History Rating: 4 out of 5 stars4/5How Emotions Are Made: The Secret Life of the Brain Rating: 4 out of 5 stars4/5The Obesity Code: the bestselling guide to unlocking the secrets of weight loss Rating: 4 out of 5 stars4/5Ultralearning: Master Hard Skills, Outsmart the Competition, and Accelerate Your Career Rating: 4 out of 5 stars4/5The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race Rating: 4 out of 5 stars4/5Peptide Protocols: Volume One Rating: 4 out of 5 stars4/5All That Remains: A Renowned Forensic Scientist on Death, Mortality, and Solving Crimes Rating: 4 out of 5 stars4/5Lifespan: Why We Age—and Why We Don't Have To Rating: 4 out of 5 stars4/5Dopamine Detox: Biohacking Your Way To Better Focus, Greater Happiness, and Peak Performance Rating: 3 out of 5 stars3/5Woman: An Intimate Geography Rating: 4 out of 5 stars4/5Anatomy 101: From Muscles and Bones to Organs and Systems, Your Guide to How the Human Body Works Rating: 4 out of 5 stars4/5Other Minds: The Octopus, the Sea, and the Deep Origins of Consciousness Rating: 4 out of 5 stars4/5Lies My Gov't Told Me: And the Better Future Coming Rating: 4 out of 5 stars4/5A Crack In Creation: Gene Editing and the Unthinkable Power to Control Evolution Rating: 4 out of 5 stars4/5The Blood of Emmett Till Rating: 4 out of 5 stars4/5Suicidal: Why We Kill Ourselves Rating: 4 out of 5 stars4/5The Unpersuadables: Adventures with the Enemies of Science Rating: 4 out of 5 stars4/5The Trouble With Testosterone: And Other Essays On The Biology Of The Human Predi Rating: 4 out of 5 stars4/5Fatal Invention: How Science, Politics, and Big Business Re-create Race in the Twenty-First Century Rating: 4 out of 5 stars4/5Jaws: The Story of a Hidden Epidemic Rating: 4 out of 5 stars4/5
Related categories
Reviews for Handbook of Pharmacogenomics and Stratified Medicine
Rating: 0 out of 5 stars
0 ratings
0 ratings0 reviews