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The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations

The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations

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The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations

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5/5 (1 evaluare)
Lungime:
234 pages
2 hours
Lansat:
Dec 1, 2015
ISBN:
9780128046708
Format:
Carte

Descriere

A volume in the Emerging Issues in Analytical Chemistry series, The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations provides analytical chemistry methods that address the latest issues surrounding cannabis-based products. The plethora of marketed strains of cannabis and cannabinoid-containing products, combined with the lack of industry standards and labelling requirements, adds to the general perception of poor quality control and limited product oversight. The methods described in this leading-edge volume help to support the manufacturing, labelling, and distribution of safe and consistent products with known chemical content and demonstrated performance characteristics. It treats analytical chemistry within the context of the diverse issues surrounding medicinal and recreational cannabis in a manner designed to foster understanding and rational perspective in non-scientist stakeholders as well as scientists who are concerned with bringing a necessary degree of order to a field now characterized by confusion and contradiction.

  • Addresses current and emerging analytical chemistry methods - an approach that is unique among the literature on this topic
  • Presents information from a broad perspective of the issues in a single compact volume
  • Employs language comprehensible to non-technical stakeholders as well as to specialists in analytical chemistry
Lansat:
Dec 1, 2015
ISBN:
9780128046708
Format:
Carte

Despre autor

Brian F. Thomas, PhD, is principal scientist of analytical chemistry and pharmaceutics at RTI International, North Carolina, United States. He has more than 20 years of experience in analytical chemistry and mass spectrometry. He is the principal investigator/co-principal investigator on two National Institute on Drug Abuse repository and purity specification contracts. His principal duties include overseeing the development of chromatographic assays and spectrophotometric assays for the qualitative and quantitative analysis of bulk chemicals or chemicals in dosage formulations, biological fluids, tissues, or other complex matrices. Dr. Thomas was recently awarded RTI’s President’s Award for his scientific contributions to the institute.

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Chapter 1

The Botany of Cannabis sativa L.

Abstract

Cannabis sativa L. is among the oldest known cultivated plants, with a long history of medical use. Cannabis produces a unique class of terpenophenolic compounds called cannabinoids, 104 of which have been isolated, the major biologically active one being Δ⁹-tetrahydrocannabinol. Cannabidiol, an antiepileptic, is also important. Cannabis is an annual, normally dioecious and occasionally monoecious, wind-pollinated species and is highly allogamous (cross-fertilization) in nature. Therefore, maintaining the efficacy of selected high Δ⁹-tetrahydrocannabinol-yielding elite varieties grown from seeds under field or greenhouse conditions is very difficult. Thus, a careful screening of elite mother clones using GC-FID and their propagation using vegetative cuttings or advanced biotechnological approaches, including micropropagation, is the most suitable way to maintain quality. This chapter describes the botany, species debate, phenotype, screening of high-yielding clones using GC-FID, indoor and outdoor cultivation, micropropagation, quality assurance of propagated plants, harvesting, processing, and

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