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October 16 2012 Issue: Pre-Symptomatic Studies in ALS: Rationale, Challenges and Approach

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1) ALS studies and 2) Topic of the month: Evaluation of polyneuropathy. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns with Dr. Michael Benatar about his paper on studies in ALS. Dr. Jennifer Fugate is reading our e-Pearl of the week about Gradenigo syndrome. In the next part of the podcast Dr. Ted Burns interviews Drs. Michelle L. Mauermann and P. James Dyck about evaluation of polyneuropathy, basics. The participants had nothing to disclose except Drs. Burns, Benatar, Fugate and Mauermann.Dr. Ted Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (35% effort); and has received research support for consulting activities with CSL Behring and Alexion Pharmaceuticals.Dr. Benatar serves as an editorial board member for Journal Watch Neurology; serves on the scientific advisory board for Cytokinetics; is a consultant for Cytokinetics and Asubio Pharmaceuticals Inc.; receives royalties from the publication of the books (1) Neuromuscular Disease: Evidence and Analysis in Clinical Neurology, (2) BluePrints in Neurology, (3) Field of Vision; receives travel funding from the (1) American Academy of Neurology, (2) Myasthenia Gravis Foundation of America; receives research support from the CytRx Corporation, Food and Drug Administration, Muscular Dystrophy Association, ALS Association, Woodruff Foundation and the NIH; involved in legal proceedings with Sutter, O'Connel and Farchione Attorneys as well as Parker Waichmann LLP. Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Mauermann receives research support from Pfizer Inc and the NIH.

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