Blood Cells

Erythrocytes (RBCs) Leukocytes (WBCs)

7.5 um diameter
biconcave disk  increased surface area
Granulocytes
for respiration (have specific granules)
Neutrophil Agranulocytes
NO nucleus Polymorphonuclear
NO organelles Neutral staining
Hemoglobin (Hb+CO= irreversible) Monocyte
Single nucleus with 3 lobes 5% of the WBCs
Carbonic anhydrase: CO2  carbonic acid 65% of circulating WBCs Largest (15 um)
 HCO3 Small specific granules Indented/horseshoe shaped nucleus
Plasma membrane: Function: kill bacteria (granulation, phagocytosis and respiratory Function: migrate and differentiate into
Band 3: anion transporter which burst) macrophage (phagocytosis and APCs)
exports HCO3 and binds ankyrin Basophil
Blood type: RBC outer membrane binds Irregular nucleus Lymphocyte (T and B cells)
CHO groups (A, B, Rh) 1% of circulating WBCs Function: defense against foreign invaders
Lifespan= 120 days Heparin and histamine granules (basophilic) and cancer cells
Anemia: lower than normal RBC count Function: binds specific antigens and antibodies  acute Only respond to one antigen
Erythrocytosis: higher than normal RBC Long-lived
count Anaphylactic shock
Thalassemia: loss of function Eosinophil
Sickle cell anemia Bi-lobed nucleus
4% of circulating WBCs
Reddish specific granules with crystalloid center (internum)
Granules contain major basic protein
Fnction: kill parasites, phagocytose Ab:Ag complexes QuickTimeª and a
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RBC Monocyte/macrophage Neutrophil

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Eosinophil
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Basophil
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