12-21. Reconsider the bearing wear data from Exercises 12-7 and 12-20.

(a) Refit the model with an interaction term. Test for significance of regression using = 0.05. (b) Use the extra sum of squares method to determine whether the interaction term contributes significantly to the model. Use = 0.05. (c) Estimate _2 for the interaction model. Compare this to the estimate of _2 from the model in Exercise 12-20. 12-20. Consider the bearing wear data in Exercise 12-7 with no interaction. (a) Test for significance of regression using _ _ 0.05. What is the P-value for this test? What are your conclusions? (b) Compute the t-statistics for each regression coefficient. Using = 0.05., what conclusions can you draw? (c) Use the extra sum of squares method to investigate the usefulness of adding x2 _ load to a model that already contains x1 _ oil viscosity. Use = 0.05.

12-51An article in the Journal of Pharmaceuticals Sciences (Vol. 80, 1991, pp. 971977) presents data on the observed mole fraction solubility of a solute at a constant temperature and the dispersion, dipolar, and hydrogen bonding Hansen partial solubility parameters. The data are as shown in the following table, where y is the negative logarithm of the mole fraction solubility, x1 is the dispersion partial solubility, x2 is the dipolar partial solubility, and x3 is the hydrogen bonding partial solubility. (a) Fit the model (b) Test for significance of regression using = 0.05. (c) Plot the residuals and comment on model adequacy

d) Use the extra sum of squares method to test the contribution of the second-order terms using _ = 0.05.