Sunteți pe pagina 1din 11

Coronary Artery Disease

Hypertension

Solid tumors Visual Memory

Leading Causes of Death


35

30

25

Percent of cases

20

15

10

0 Pneumonia/Flu Heart Defects Dementia Coronary Artery Disease Cancer Stroke

Down Syndrome

General Population

Patients with high cholesterol, high incidence of diabetes and obesity Minimal Hypertension Autopsy studies showing minimal coronary plaque Lancet Study: Incidence of ischemic heart disease %7

Increased incidence of leukemia (RR 10-18) Overall mortality from leukemia (RR 1.5-3) 92% of cases are diagnosed before age 20 Leukemia accounts for more than 50% of all cancers in patients with Down Syndrome

Cancer Type Testicular Colorectal Breast Lung Prostate Cervical Leukemia Non-Leukemia Malignancy

Number of cases 26 26 25 17 5 0 345 344

Standardized mortality odds ratio 3.23 0.08 0.04 0.02 0.08 0.00 1.57 0.07

o o o o

Increased pain tolerance Behavior as sign of underlying disease Self talking Visual Memory

Identification of genetic protection from cancer Understanding of Vascular Physiology Implication of benefits for adults with Down Syndrome

S-ar putea să vă placă și