Hemofarm Vademekum Engleska Verzija Za 2013

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A A02 A02B A02BA A02BA02
ALIMENTARY TRACT & METABOLISM DRUGS FOR ACID RELATED DISORDERS DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX (GORD) H2-RECEPTOR ANTAGONISTS ranitidine
Ranitidine
Antiulcerant
Brand name Ranitidine ATC DDD INN ranitidine hydrochloride Pregnancy B Lactation Unknown effects on infants exposed. No evidence of harmfulness. Excreted into milk.
A02BA02 O, P 0,3 g Form and package Film coated tablets 20 x 150 mg eff. tablets 20 x 150 mg inj. 5 x 50 mg/2 ml
INDICATIONS Gastric ulcer Duodenal ulcer Gastrooesophageal reflux disease (GORD) Erosive oesophagitis. Zollinger-Ellison syndrome and other related conditions (systemic mastocytosis ) Other conditions where is hyperacidity important disturbance for patient Bleeding from upper part of digestive tract (only for parenteral form)
A02BA03 famotidine
Famotidine
H2-receptor antagonist
Brand name Famotidine ATC A02BA03 Form and package Film coated tablets 30 x 20 mg film coated tablets 30 x 40 mg DDD O, P 0,04 g
INN famotidine Pregnancy B Lactation Caution, the lowest excretion of all H2-receptor antagonists
INDICATIONS Gastric and duodenal ulcers Reflux oesophagitis Zollinger-Ellison syndrome Non-ulcus dyspepsia
A02BC A02BC01
PROTON PUMP INHIBITORS omeprazole
Omeprazol
Brand name Omeprazol ATC A02BC01 DDD O 20 mg
proton pump inhibitor

INN omeprazole Pregnancy C Lactation It is excreted into breast milk, avoid
Form and package gastroresistant capsules 14 x 20 mg gastroresistant capsules 15 x 20 mg
INDICATIONS Omeprazole gastroresistant capsules are indicated for: Adults: treatment of duodenal ulcer prevention of relapse of duodenal ulcers treatment of peptic ulcers prevention of relapse of peptic ulcers treatment of peptic ulcers caused by Helicobacter pylori (H. pylori) in combination with an appropriate antibiotic
treatment of duodenal and peptic ulcers resulting from the use of NSAIDs prevention of peptic and duodenal ulcers in patients on NSAIDs who are at risk treatment of reflux oesophagitis long-term therapy in patients with healed reflux oesophagitis treatment of symptomatic gastro-oesophageal reflux disease treatment of Zollinger-Ellison syndrome Children (over 1 year and BW 10 kg): treatment of reflux oesophagitis symptomatic treatment of heartburn and regurgitation of acid in gastro-oesophageal reflux disease Children (over 4 years) and adolescents In combination with antibiotic treatment of duodenal ulcers caused by H. pylori
A02BC03
lansoprazole
Sabax
proton pump inhibitor
Brand name Sabax ATC A02BC03 DDD O 30 mg
INN lansoprazole Pregnancy B Lactation Potential toxic. Possible suppression of gastric secretion
Form and package capsules 28 x 15 mg capsules 14 x 30 mg
INDICATIONS Gastrooesophageal reflux Benign gastric ulcus Duodenal ulcer Dyspepsia with hyperacidity Therapy and prophylaxis of ulcus associated with long term use of NSAID Hypersecretory conditions including Zollinger-Ellison syndrome Reflux oesophagitis Helicobacter pylori eradication (in combination with appropriate antibiotics)
Laktuloza
Osmotic laxative
Brand name Laktuloza ATC A06AD11 DDD O 6,7 g
INN lactulose Pregnancy B Lactation Can be used.
INDICATIONS Chronic constipation. Hepatic encephalopathy (portal encephalopathy); hepatic coma.
Form and package Bottle with 200 ml syrup Bottle with 500 ml syrup
A10B ORAL ANTIDIABETICS (drugs which lowered glucose level in blood) A10BA BIGUANIDE ANTIDIABETICS A10BA02 metformin
Gluformin
oral antidiabetic INDICATIONS Noninsulin-dependent diabetes mellitus (type II, NIDDM), especially in overweight patients, whose glucose metabolism are not adequately controlled with diet and exercise. For treating noninsulin-dependent diabetes mellitus (Type II) in combination with sulfonylureas; strictly take care about contraindications. In patients with normal body weight and NIDDM, Gluformin can used like monotherapy, or in combination with sulphonylurea antidiabetics, and on this way is possible to avoid use of insulin. Gluformin also might be combined with insulin. It is very important that through therapy with Gluformin, body weight not enlarged; in some cases body weight can to fall off.
Brand name Gluformin ATC A10BA02 Form and package tablets 30 x 500 mg tablets 30 x 1000 mg DDD O2g
INN metformin hydrochloride Pregnancy B Lactation Avoid
A10BB SULPHONYLUREA ANTIDIABETICS A10BB09 gliclazide
Diprian
oral antidiabetic
Brand name Diprian ATC A10BB09 Form and package tablets 30 x 80 mg DDD O 0,16 g
INN gliclazide Pregnancy C Lactation Avoid
INDICATIONS Noninsulin-dependent diabetes mellitus (type II, NIDDM) in adults, whose glucose metabolism are not adequately controlled with diet.
Reguly
oral antidiabetic
Brand name Reguly ATC A10BX02 Form and package tbl. 30 x 0,5 mg tbl. 30 x 1 mg tbl. 30 x 2 mg DDD O 4 mg
INN repaglinide Pregnancy C Lactation No data, avoid
INDICATIONS Repaglinide is indicated in patients with type II diabetes (insulin-independent diabetes mellitus) whose hyperglycaemia can no longer satisfactorily controlled regime of diet, weight loss and physical activity. Repaglinide in combination with metformin, is also indicated in patients with type II diabetes whose blood glucose is not properly regulated using only metformin. Begin therapy in addition to diet and physical activity, and adjust to meal.
B BLOOD AND FORMING ORGANS, DRUGS FOR TREATMENT OF DISEASES OF BLOOD AND FORMING ORGANS B01 ANTITHROMBOTIC DRUGS (ANTICOAGULANTS) B01A ANTITHROMBOTIC DRUGS (ANTICOAGULANTS) B01AC INHIBITORS OF THROMBOCYTES AGGREGATION, EXCLUDING HEPARINE B01AC04 clopidogrel
Clopidix
Inhibitor of thrombocytes aggregation
Brand name Clopidix ATC B01AC04 DDD O 75 mg
INN clopidogrel Pregnancy B Lactation Avoid
Form and package film-coated tablets 28 x75mg
INDICATIONS Clopidogrel is used in adults for the prevention atherotrombotic events: - Patients who have had a myocardial infarction (from a few up to 35 days), ischemic stroke (between 7 days to a maximum of 6 months) or have a confirmed peripheral artery disease. - In patients with acute coronary syndrome: - Acute coronary syndrome without ST-segment elevation (unstable angina or nonQ myocardial infarction), including patients with stents after percutaneous coronary intervention, in combination with acetylsalicylic acid. - Acute myocardial infarction with ST-segment elevation, in combination with aspirin in patients who have conditions for treatment with thrombolytics.
B01AC05
ticlopidine
Ticlodix
Inhibitor of thrombocytes aggregation
Brand name Ticlodix ATC B01AC05 DDD O 0,5 g
INN ticlopidine Pregnancy B Lactation Avoid
Form and package film tablets 30 x 250 mg
INDICATIONS Ticlodix tablets used in the secondary prophylaxis of thromboembolic complications: Cerebrovascular disease, Ischemic heart disease, Peripheral arterial disease with claudication, After coronary artery bypass In patients on hemodialysis with arteriovenous cannula, Surgical procedures using the extracorporeal circulation. Ticlodix should be used in patients who can not use aspirin (Ticlodix use is related to the manifestation of life-threatening side effects of blood dyscrasia, including thrombotic thrombocytopenic purpura TTP).
B03 B03X B03XA B03XA01
ANTI-ANAEMIC PREPARATIONS OTHER ANTI-ANAEMIC PRODUCTS OTHER ANTI-ANAEMIC PRODUCTS epoetinum zeta
Treatment of severe anaemia of renal origin accompanied by clinical symptoms in adult patients with renal insufficiency not yet undergoing dialysis. Treatment of anaemia and reduction of transfusion requirements in adult patients receiving chemotherapy for solid tumours, malignant lymphoma or multiple myeloma, and at risk of transfusion as assessed by the patients general status (e.g. cardiovascular status, pre-existing anaemia at the start of chemotherapy). Eqralys can be used to increase the yield of autologous blood from patients in a predonation programme. Its use in this indication must be balanced against the reported risk of thromboembolic events. Treatment should only be given to patients with moderate anaemia (haemoglobin (Hb) 10-13 g/dl [6.2-8.1 mmol/l], no iron deficiency), if blood saving procedures are not available or insufficient when the scheduled major elective surgery requires a large volume of blood (4 or more units of blood for females or 5 or more units for males). Eqralys can be used to reduce exposure to allogenic blood transfusions in adult non iron deficient patients prior to major elective orthopaedic surgery, having a high perceived risk for transfusion complications. Use should be restricted to patients with moderate anaemia (e.g. Hb 10 - 13 g/dl) who do not have an autologous predonation programme available and with an expected blood loss of 900 to 1800 ml.
Eqralys
Brand name Eqralys ATC B03XA01
Epoetinum zeta
INN epoetinum zeta DDD P 1000 I.U. Pregnancy C No data available Lactation
Form and package solution for injection 10000 I.U./1ml solution for injection 20000 I.U./0,5ml solution for injection 30000 I.U./0,75ml solution for injection 6 x 1000 I.U./0,3ml solution for injection 6 x 2000 I.U./0,6ml solution for injection 6 x 4000 I.U./0,4ml
Avoid, no data available
INDICATIONS Treatment of anaemia associated with chronic renal failure in adult and paediatric patients on haemodialysis and adult patients on peritoneal dialysis.
B05 B05A B05AA07
SOLUTION FOR BLOOD SUBSTITUTE AND PERFUSION SOLUTIONS BLOOD AND KRV I SIMILAR SOLUTION hydroxyethyl starch, sodium chloride
Hetasorb 6% Hetasorb10%
plasma expander
Brand name Hetasorb 6% Hetasorb 10 % ATC B05AA07 Form and package Inf.solution 500 ml Inf. solution 500 ml DDD INN HAES , NaCl Pregnancy Not recomended Lactation Caution, Not enough data
INDICATIONS Treatment and prevention of hypovolemia and shock after operations, injuries, infections and burns. Normovolemic hemodilution. To compensate for the volume of cerebral disorders, retinal and cochlear blood flow.
B05B I.V. SOLUTIONS B05BA SOLUTIONS FOR PARENTERAL NUTRITION B05BA01 amino acids
Aminosol 10%
infusion solution
Brand name Aminosol 10% ATC B05BA01 Form and package bottle 500 ml DDD
INN amino acids Pregnancy C Lactation Avoid
INDICATIONS Aminosol 10% infusion solution used together with fat emulsions, electrolytes and carbohydrates as a part of partial or total parenteral nutrition; for prophylaxis and therapy of protein and water loss in cases when the inability of enteral nutrition is present. Infusion solution is indicated in severe gastroinestinal diseases (ileus, peritonitis, malapsorption, bowel inflammation, pancreatitis, enterocutaneous phystulas), hypercatabolic status (traumas, burns, sepsis) and other diseases (anorexia nervosa, malignant diseases), in preoperative and postoperative period.
B05BA10 aminoacids, minerals
Aminosol 15%
infusion solution
Brand name Aminosol 15% ATC B05BA01 Form and package bottle 500 ml DDD
INDICATIONS Aminosol 15% infusion solution used together with fat emulsions, electrolytes and carbohydrates as a part of partial or total parenteral nutrition; for prophylaxis and therapy of protein and water loss in cases when the inability of enteral nutrition is present. Infusion solution is indicated in severe gastroinestinal diseases (ileus, peritonitis, malapsorption, bowel inflammation, pancreatitis, enterocutaneous phystulas), hypercatabolic status (traumas, burns, sepsis) and other diseases (anorexia nervosa, malignant diseases), in preoperative and postoperative period.
Aminosol 10% E
infusion solution
Brand name Aminosol 10% E ATC B05BA10 Form and package bottle 500 ml DDD
INDICATIONS Aminosol 10% E infusion solution used together with fat emulsions, electrolytes and carbohydrates as a part of partial or total parenteral nutrition; for prophylaxis and therapy of protein and water loss in cases when the inability of enteral nutrition is present. Infusion solution is indicated in severe gastroinestinal diseases (ileus, peritonitis, malapsorption, bowel inflammation, pancreatitis, enterocutaneous phystulas), hypercatabolic status (traumas, burns, sepsis) and other diseases (anorexia nervosa, malignant diseases), in preoperative and postoperative period.
B05BA.01 alanine, arginine, cysteine, phenilalanine, glycine, histidine, isoleucine, leucine, lysine, methionin, proline, serine, acetate acid, threonine, triptophan, valine
Hepasol 8%
infusion solution
Brand name Hepasol 8 % ATC B05A01 Form and package bottle 1 x 500 ml DDD
INN alanine, arginine, cysteine, phenilalanine, glycine, histidine, isoleucine, leucine, lysine, methionin, proline, serine, acetate acid, threonine, triptophan, valine Pregnancy C Lactation Avoid
INDICATIONS Liver insufficiance with or without disturbances of cerebral functions (encephalopathy) Hepatic coma or precomatous conditions.
B05BC SOLUTIONS PRODUCING OSMOTIC DIURESIS B05BC01 mannitol
Mannitol
osmotic diuretic
Brand name Mannitol ATC B05BC01 Form and package Mannitol 10 % bottle 500 ml Mannitol 20 % bottle 250 ml DDD P 40 g
INN mannitol Pregnancy No data available Lactation Avoid
INDICATIONS Prevention of anuria after: incidental transfusion, large trauma, bleeding, surgery and burns Increased intracranial pressure: brain tumors, brain oedema, head injuries Increased intraocular pressure Poisoning with barbiturates and salicilates Heavy oedema, ascites caused by liver cirrhosys with use of saliuretics and aldosterone. Hypoglicemic coma
B05C IRRIGATING SOLUTIONS B05CX OTHER IRRIGATING SOLUTIONS B05CX10 mannitol, sorbitol
Ispirol
For Flushing of the bladder
Brand name Ispirol ATC B05CX10 Form and package Solution for external use (PVC bag) 1 x 5000 ml (0,54%+2,70%) DDD
INN mannitol, sorbitol Pregnancy C Lactation Caution
INDICATIONS Ispirol is only used in urology to flush the bladder during transurethral resection of the prostate and other transurethral procedures.
C C01 C01B C01BC C01BC03
CARDIOVASCULAR SYSTEM CARDIAC THERAPY ANTI-ARRHYTHMICS, CLASS I AND III Anti-arrythmics, group I C propafenon
Propafen
Brand name Propafen ATC C01BC03
anti-arrhythmic (class I C)
INN propafenon DDD O, P 0,3 g Pregnancy C Lactation Avoid
Form and package Film coated tablets 50 x 150 mg Film coated tablets 50 x 300 mg inj. 10 x 35 mg/10 ml
INDICATIONS All form of ventricular and supraventricular extrasystolas Ventricular and supraventricular tachicardias and tachiarrhythmias Wolff-Parkinson-White syndrome (WPW).
C01D VASODILATATORS USED IN CARDIAC DISEASES C01DA ORGANIC NITRATES C01DA05 pentaerithrityltetranitrate (pentanitrole)
Dilcoran 80
antianginic with prolonged action
Brand name Dilcoran 80 ATC C01DA05 Form and package retard tablets 20 x 80 mg DDD O 0,12 g
INN pentaerithrityltetranitrate (pentanitrole) Pregnancy C Lactation Avoid
INDICATIONS Long term therapy of ischaemic heart disease Prophylaxis of angina pectoris Additional therapy: chronic cor pulmonare and chronic heart failure
C01DA14 isosorbide mononitrate
Monizol
antianginic (vasodilatator)
Brand name Monizol ATC C01DA14 Form and package tablets 30 x 20 mg tablets 30 x 40 mg DDD O 0,04 g
INN Isosorbide mononitrate Pregnancy C Lactation Avoid
INDICATIONS Prophylaxis of angina pectoris attack Coronary arteries spasm removal (Prinzmetal angina) Chronic heart failure
C02 C02A C02AB C02AB02
ANTIHYPERTENSIVES CENTRALY ACTING ANTIADRENERGICS METHYLDOPA methyldopa
Methyldopa
Antihypertensive
Brand name Methyldopa ATC C02AB02 Form and package Film coated tablets 20 x 250 mg DDD O1g INN methyldopa Pregnancy B Lactation Caution
INDICATIONS Hypertension of different ethiology (except phaeochromocythoma).
C03 C03B C03BA C03BA11
DIURETICS WEAK DIURETICS, EXCLUDING THIAZIDES MONOCOMPONENT SULPHONAMIDE DIURETICS indapamide
Indapres
Diuretic
Brand name Indapres ATC C03BA11 Form and package tablets 30 x 2,5 mg DDD O 0,0025 g INN indapamide Pregnancy B Lactation Avoid
INDICATIONS Arterial hypertension (mild to moderate, like monotherapy, or in combination with other antihypertensives) Water and electrolytes retention (oedema in congestive heart diseases).
Indapres SR
diuretic
Brand name Indapres SR ATC C03BA11 Form and package Film coated retard tablets 30 x 1,5 mg DDD O 0,0025 g
INN indapamide Pregnancy B Lactation Avoid
INDICATIONS Therapy and control of essential hypertension.
C03E C03EA C03EA01 C03EA01
POTASSIUM-SPARING AGENTS WITH OTHER DIURETICS THIAZIDES AND POTASSIUM-SPARING DIURETICS PRODUCTS WHICH CONTENTS CORTICOSTEROIDS hydrochlorothiazide, amiloride hydrochloride
Hemopres
Brand name Hemopres ATC C03EA01
diuretic combination
INN hydrochlorothiazide,amiloride hydrochloride DDD O (0,05+0,005)g Pregnancy D Lactation Avoid
INDICATIONS Arterial hypertension Congestive heart failure with hypokaliemia Liver cirrhosys with ascites
Form and package tablets 40 (50+5) mg
C04AE ERGOT ALCALOIDS C04AE01 ergoloid mesilate (dihydroergotoxine)
Redizork
Vasodilatator
Brand name Redizork ATC C04AE01 Form and package tablets 20 x 1,5 mg tablets 20 x 4,5 mg DDD O, P 0,003 g
INN dihydroergotoxine Pregnancy X Lactation Avoid
INDICATIONS Senile cerebral insufficiency Acute ischaemic stroke Status after apoplectic stroke or traumatic brain damage. Hypertension in older persons, in patients with cerebrovascular insufficiency
C07 C07A C07AB C07AB02
BETA-BLOCKING AGENTS BETA-BLOCKING AGENTS SELECTIVE BETA-BLOCKING AGENTS metoprolol
Presolol
Brand name Presolol ATC C07AB02
beta1 receptors blocker
INN metoprolol tartrate DDD O, P 0,15g Pregnancy C, D in 2nd and 3rd trimester Lactation Caution
Form and package f. c. tablets 30 x 100 mg f. c. tablets 28 x 50 mg f. c. tablets 56 x 50 mg inj. 5 x 5ml/5mg
INDICATIONS Hypertension Angina pectoris Myocardial infarction and secondary prevention of myocardial infarction Arrhythmias (supraventricular tachiarrhytmias) Hyperthireoidism (like additional therapy) Prevention of migraines Chronic heart failure
Tensec
selective blocator beta adrenergic receptors
Brand name Tensec ATC C07AB07 DDD O 10 mg
INN bisoprolol Pregnancy C Lactation Caution, excreted in milk
INDICATION Hipertension Chronic stable angina pectoris.
Form and package film tablets 30 x 5 mg film tablets 30 x 10 mg
Tensec Plus
selective blocator beta adrenergic receptors with thiazides
Brand name Tensec Plus ATC C07BB07 Form and package film tablets 30 x (5 mg+12,5 mg) DDD
INN Bisoprolol, HCTZ Pregnancy C Lactation Caution, excreted in milk
INDICATIONS Essential hypertension The fixed combination is indicated in patients in whom blood pressure is not adequately controlled by the individual components - bisoprolol and hydrochlorothiazide.
C07AG BLOCATORS OF ALPHA AND BETA ADRENERGIC RECEPTORS C07AG02 carvedilol
Milenol
alpha and beta blocker
Brand name Milenol ATC C07AG02 Form and package tablets 28 x 12,5 mg tablets 28 x 25 mg DDD O 0,0375 g
INN carvedilol Pregnancy C Lactation Avoid
INDICATIONS Mild to moderate arterial hypertension Angina pectoris Chronic heart failure
C08 C08C C08CA C08CA01
CALCIUM ANTAGONISTS SELECTIVE CALCIUM ANTAGONISTS WITH DIRECT ACTION ON HEART DIHYDROPIRIDINE DERIVATES amlodipine
Vazotal
Brand name Vazotal ATC C08CA01
calcium antagonist
INN amlodipine DDD O 0,005 g Pregnancy C Lactation Avoid
INDICATIONS Arterial hypertension Stable, chronic angina pectoris Vasospastic angina Prinzmetal type
Form and package tablets 20 x 5 mg tablets 20 x 10 mg
Cornelin
calcium antagonist
Brand name Cornelin ATC C08CA13 DDD 10 mg O
INN lercanidipine Pregnancy B Lactation Avoid, low concentration recorded in milk
INDICATIONS Mild to moderate essential arterial hypertension
Form and package film tablets 28 po 10 mg film tablets 28 po 20 mg
C08D SELECTIVE CALCIUM ANTAGONISTS WITH DIRECT ACTION ON HEART C08DA PHENYLALKILAMINE DERIVATES C08DA01 verapamil
Verapamil
calcium antagonist
Brand name Verapamil ATC C08DA01 Form and package Film coated retard tablets 30 x 40 mg film coated retard tablets 50 x 80 mg DDD O 0,24 g
INN verapamil hydrochloride Pregnancy C Lactation Caution, excretion in milk
INDICATIONS Angina pectoris (all types) Arrythmias (chronic flutter and supraventricular fibrilation) Prophylaxis of paroxismal supraventricular tachycardias Essential hypertension
Cortiazem retard
calcium antagonist
Brand name Cortiazem retard ATC C08DB01 DDD O 0,24 g
INN diltiazem Pregnancy C Lactation Avoid
Form and package Retard tablets 30 x 90 mg
INDICATIONS Chronic treatment of arterial hypertension Chronic treatment of coronary artery disease Prophylaxis of angina pectoris Vasospastic angina (Prinzmetals angina) Angina pectoris in the situation after myocardial infarction Non Q infarct
C09 C09A C09AA C09AA01
AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM ACE INHIBITORS, PLAIN ACE INHIBITORS, PLAIN captopril
Zorkaptil
ACE inhibitor
Brand name Zorkaptil ATC C09AA01 Form and package tablets 40 x 12,5 mg tablets 40 x 25 mg tablets 40 x 50 mg DDD O 0,05g INN captopril Pregnancy D Lactation Caution
INDICATIONS Arterial hypertension (monotherapy or in combination with thiazide diuretics) Congestive heart failure (with cardiotonics and diuretics) Myocardial infarction Diabetic nephropathia.
C09AA05
ramipril
Prilinda
ACE inhibitor
Brand name Prilinda ATC C09AA05 DDD O 2,5 mg
INN ramipril Pregnancy C, D in 2. and 3. trimester Lactation Not enough data, it is probably in the milk
Form and package Tablets 28 x 2,5 mg Tablets 28 x 5 mg
INDICATIONS Essential hypertension (mild to moderate) Congestive heart failure Congestive heart failure after acute myocardial infarction Prophylaxis: reducing the risk of myocardial infarction, stroke or cardiovascular death or need for revascularization procedures in patients with clinically proven cardiovascular disease (with or without previous MI), stroke or peripheral vascular disease Prophylaxis: reducing the risk of myocardial infarction, stroke or cardiovascular death or need for revascularization procedures in diabetic patients with clinically proven previous cardiovascular disease The initial non-diabetic or diabetic nephropathy Manifest non-diabetic or diabetic nephropathy
C09AA02 enalapril
Prilenap
antihipertensive
Brand name Prilenap ATC C09AA02 Form and package tablets 20 x 10 mg tablets 20 x 20 mg DDD O 0,01 g
INN enalapril maleate Pregnancy D Lactation Caution
INDICATIONS Arterial hypertension Congestive heart failure.
C09B ACE INHIBITORS, COMBINATION C09BA ACE INHIBITORS AND DIURETICS C09BA02 enalapril, hydrochlorothiazide
Prilenap HL, Prilenap H

antihipertensive
Brand name Prilenap HL, Prilenap H ATC C09BA02 Form and package tablets 20 x (10+12,5) mg tablets 20 x (10 + 25) mg DDD
INN enalapril, hydrochlorothiazide Pregnancy D Lactation Avoid
INDICATIONS All forms of essential hypertension, when combined therapy is necessary
C09AA06
quinapril
Hemokvin
ACE-ihibitor
Brand name Hemokvin ATC C09AA06 DDD O, P, 0,015 g
INN quinapril Pregnancy C (D in 2. and 3. trimester) Lactation Caution
INDICATION Arterial hypertension Heart failure Myocardial infarction
Form and package film tablets 20 po 10 mg film tablets 20 po 20 mg
C09BA06
quinapril, hydrochlorothiazide
Hemokvin plus
quinapril, hydrochlorothiazide
Brand name Hemokvin plus ATC C09BA06 DDD O 2,5 mg
INN quinapril, hydrochlorothiazide Pregnancy C (D in 2. and 3. trimester) Lactation Caution
INDICATION Hemokvin Plus is indicated for the treatment of all forms of essential hypertension, when needed combination therapy (for patients whose blood pressure was previously not normalized with individual ingredients of the preparation).
Form and package Film tabletas 20 x (20,0+12,5 mg)
C09AA08 cilazapril
Zobox
ACE inhibitor
Brand name Zobox ATC C09AA08 DDD O 2,5 mg
INN cilazapril Pregnancy D Lactation Avoid. Not enough data in literature
INDICATIONS Therapy of hypertension Therapy of congestive heart failure ( in combination with digitalis and/or diuretics).
Form and package Film coated tablets 30 x 2,5mg Film coated tablets 30 x 5mg
C09C ANGIOTENSIN II RECEPTOR ANTAGONISTS, PLAIN C09CA ANGIOTENSIN II RECEPTOR ANTAGONISTS, PLAIN C09CA01 losartan
Erynorm
angiotensin II receptor antagonist
Brand name Erynorm ATC C09CA01 DDD 50 mg O
INN losartan Pregnancy C (D in 2nd and 3rd trimester). When pregnancy is detected, losartan should be discontinued as soon as possible. Lactation Because of the potential for adverse effects on the nursing infant, losartan should be avoided
Form and Package Film coated tablets 28 x 50 mg Film coated tablets 28 x 100 mg
INDICATIONS Hypertension Hypertensive patients with left ventricular hypertrophy (In hypertensive patients with left ventricular hypertrophy a reduced risk of stroke was demonstrated. The data do not support the use of losartan for this indication in black patients) Renal protection in type 2 diabetic patients with nephropathy (macroalbuminuria) (Losartan delays the progression of renal disease as measured by a reduction in the combined incidence of doubling of serum creatinine, end stage renal disease (need for dialysis or renal transplantation) or death; and to reduce proteinuria)
Irbenida
angiotensin II receptor antagonist
Brand name Irbenida ATC C09CA04 DDD O 0,15 g
INN irbesartan Pregnancy C (first trimester), D Lactation Avoid
INDICATIONS Irbesartan is used in the treatment of essential hypertension diabetic nephropathy in patients with hypertension and type 2 diabetes as part of the antihypertensive regimen
Form and Package f.c. tbl. 30x 150 mg f.c. tbl. 30 x 300 mg
C09DA01
losartan potassium + hydrochlorothiazide
Erynorm plus
angiotensin II receptor antagonist, hydrochlorothiazide
Brand name Erynorm plus ATC C09DA01 DDD 1 tablets
INN losartan-potassium, hydrochlorothiazide Pregnancy C, D in the second and 3 trimester. Discontinue drug if pregnancy is established Lactation Potentially toxic to children. Avoid it.
INDICATIONS Erynorm plus tablets are indicated for the treatment of hypertension in patients whose blood pressure can not be adequately controlled individually applied losartan or hydrochlorothiazide
Form and Package Film-coated tablets 28 x (50 mg+12,5 mg)
C09DA04
irbesartan+hidrohlorotiazid
Irbenida plus
angiotensin II receptor antagonist, hydrochlorothiazide
Brand name Irbenida plus ATC C09DA04 Form and Package f.c. tbl. 30x (150 mg+12,5 mg) f.c. tbl. 30x (300 mg+12,5 mg) DDD
INN Irbesartan, hydrochlorothiazide Pregnancy C(first trimester), D Lactation Avoid
INDICATIONS It is used in the treatment of essential hypertension. This fixed combination is intended for adults whose blood pressure is not adequately regulated using only irbesartan or hydrochlorothiazide only.
C10 C10A C10AA C10AA01
LIPID MODIFYING AGENTS (HYPOLIPEMICS) LIPID MODIFYING AGENTS, PLAIN HMG CoA REDUCTASE INHIBITORS simvastatin
Cholipam
Hypolipemic
Brand name Cholipam ATC C10AA01 Form and Package Film coated tablets 20 x 10mg film coated tablets 20 x 20mg DDD O 0,015g INN simvastatin Pregnancy X Lactation Avoid
INDICATIONS Hyperlipidemia Type IIa, IIb and III Coronary heart disease (primary and secondary prevention).
C10AA05
atorvastatin
Hipolip
Hypolipemic 10 years with primary hypercholesterolemia, including family hypercholesterolemia (heterozygous form) and combined (mixed) hyperlipidaemia (corresponding types IIa and IIb according Fredrickson classification), when not achieved the desired response to diet and other non-pharmacological measures. In addition, atorvastatin is indicated for the reduction of elevated total cholesterol and LDL cholesterol in adults with homozygous familiar hypercholesterolemia, in addition to other lipid-lowering treatments (eg LDL apheresis) in situations where these treatments are not available. Prevention of cardiovascular disease Prevention of cardiovascular events in adult patients who have a high estimated risk of first cardiovascular events, with correction of other risk factors.
Brand name Hipolip ATC C10AA05 Form and Package F.c. tablets 30 x 10 mg F.c. tablets 30 x 20 mg F.c. tablets 30 x 40 mg F.c. tablets 30 x 80 mg DDD O 20 mg
INN atorvastatin Pregnancy X Lactation Contraindicated. There are potentially serious adverse effects
INDICATIONS Hypercholesterolemia Atorvastatin is indicated as an adjunct to diet to reduce elevated total cholesterol, LDL-cholesterol, apolipoprotein B, and triglyceride levels in adults, adolescents and children older than
G G02 G02A G02AB G02AB01
GENITO URINARY SYSTEM AND SEX HORMONES (DRUGS FOR THE TREATMENT OF GENITO URINARY SYSTEM AND SEX HORMONES) OTHER GYNECOLOGICALS OXYOTOCICS ERGOT ALKALOIDS methylergometrine
Methylergometrine
Uterotonic INDICATIONS Postpartum and postabortion haemorrhage, haemorrhage after cesarean section, menorrhage, metrorrhage, uterine atony.
Brand name Methylergometrine ATC G02AB01 Form and Package drops 10 ml ( 0,25 % mg/ ml ) amp. 50 x 0,1 mg / 1 ml amp. 50 x 0,2 mg / 1ml DDD O, P 0,0002g
INN methylergometrine Pregnancy D Lactation Avoid, possible inhibitory effect on prolactin secretion
G04 G04BE G04BE03
UROLOGICALS Drugs used for erectile dysfunction sildenafil
Sildena
Drugs used in erectile dysfunction
Brand name Sildena ATC G04BE03 DDD O 50 mg
INN sildenafil Pregnancy X Lactation Contraindicated
Form and package film tablets 1 x 25 mg film tablets 1 x 50 mg film tablets 1 x 100 mg
INDICATIONS Treatment of erectile dysfunction, which is the inability to achieve or maintain penile erection required for satisfactory sexual activity. For the effect of sildenafil is required sexual stimulation
G04C GO4CA G04CA02
DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY ANTAGONISTS OF ALPHA-ADRENERGIC RECEPTORS tamsulosin
Betamsal
Therapy of BPH
Brand name Betamsal ATC G04CA02 DDD O 0,4mg
INN tamsulosin Pregnancy tamsulosin is solely intended for use in men. Lactation tamsulosin is solely intended for use in men.
INDICATIONS Treatment of functional symptoms caused by benign prostatic hyperplasia (BPH).
Form and package Hard caps. with modified release 30 x 0,4 mg
G04CB TESTOSTERONE-5-ALPHA REDUCTASE INHIBITORS G04CB01 finasteride
Zerlon
androgen synthesis inhibitor
Brand name Zerlon ATC G04CB01 Form and Package Film coated tablets 30 x 5 mg DDD O 0,005 g
INN finasteride Pregnancy X Lactation Avoid
INDICATIONS The treatment and control of benign prostatic hyperplasia (BPH) in men with an enlarged prostate.
H H02 H02A H02AB H02AB04
SYSTEMIC HORMONAL PREPARATIONS EXCLUDING SEX HORMONES AND INSULINES CORTICOSTEROIDS FOR SYSTEMIC USE CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN GLUCOCORTICOIDS methylprednisolone
Lemod Depo
Corticosteroid
Brand name Lemod depo ATC H02AB04 DDD O 0,0075 g; P 0,02 g INN methylprednisolone Pregnancy B Lactation Caution
Form and Package inj. depot 10 x 1 ml/40 mg tablets 20 x 4 mg eff. tablets 20 x 16 mg
INDICATIONS Rheumatoid arthritis and osteoarthritis Bursitis, tendonitis, tenosynovitis, epicondylitis Localized neurodermatitis, hypertrophic lichen planus, necrobiosis lipoidica diabeticorum, lipoid necrosis, alopecia areata, systemic lupus erythematosus, acute and chronic contact dermatitis and systemic collagenosis Bronchial asthma and allergic rhinitis Acute exacerbations of multiple sclerosis Leukemias and lymphomas
Lemod Solu
Corticosteroid INDICATIONS Severe or incapacitating allergic conditions Critical cardiovascular conditions (shock not responding to standard treatment) Cerebral oedema, Tuberculous meningitis, acute exacerbations of multiple sclerosis Endocrine and metabolic conditions (congenital adrenal hyperplasia, nonsuppurative thyroiditis, hypercalcemia associated with cancer) Rheumatic diseases, collagen disorders and ulcerative colitis Respiratory diseases (sarcoidosis, berylliosis, pulmonary oedema, Loefflersyndrome not manageable by other means). Leukemias and lymphomas Cytostatic-induced nausea and vomiting Acute severe exacerbations of lupus erythematosus, exfoliative, contact dermatitis and generalized neurodermatitis Organ transplant.
Brand name Lemod Solu ATC H02AB04 DDD O 0,0075 g; P 0,02 g
INN methylprednisolone Pregnancy B
Form and Package inj. solu 15 x 20 mg with solvent inj. solu 15 x 40 mg with solvent inf. solu 1 x 125 mg with solvent inf. solu 1 x 500 mg with solvent
Lactation
Caution
Lemod Solu dabble-o-vial

Corticosteroid
Brand name Lemod Solu dabble-o-vial ATC DDD H02AB04 O 0,0075 g; P 0,02 g Form and Package lyophilisate for solution for injection with solvent for parenteral use, 40 mg lyophilisate for solution for injection with solvent for parenteral use, 125 mg INN methylprednisolone Pregnancy B Lactation Caution
INDICATIONS Lemod- Solu is indicated for the treatment of conditions when quick and intensive effect is needed, such as: Allergic diseases and reactions - bronchial asthma, status asthmaticus, angioneurotic oedema, anaphylaxis, serum sickness, atopic dermatitis Rheumatic diseases - rheumatoid arthritis, posttraumatic osteoarthritis, bursitis, tendovaginitis, epicondilitis, fibrositis, psoriatic arthritis and gout, ankylosing spondylitis Collagenoses - systemic lupus erythematosus, acute rheumatic carditis, systemic dermatomiositis
Dermatologic diseases - pemphigus, exfoliative dermatitis, bullous dermatitis herpetiformis, erythema multiforme, mycosis fungoides, severe forms of psoriasis and seborrheic dermatitis Gastrointestinal diseases - ulcerative colitis, Crohns disease Respiratory tract diseases - fulminant or disseminated tuberculosis (with appropriate antituberculous therapy), symptomatic sarcoidosis, Loefflers syndrome, diffuse interstitial fibrosis Nervous system diseases - acute exacerbations of multiple sclerosis Inflammatory eye diseases - Uveitis, diffuse scleritis, deep parenchymatous keratitis, optic nerve neuritis, chorioretinitis, sympathetic ophthalmia, herpes zoster ophthalmicus Lymphomas and leukemias - As a component of complex therapeutic protocols Renal diseases - Nephrotic syndrome without uremia, idiopathic or in lupus erythematosus Cerebral oedema - After injury, operation or as a consequence of brain tumor Organ transplant - Transplant rejection reactions
J J01 J01A J01AA J01AA02
ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE TETRACYCLINES TETRACYCLINES doxycycline
Doksiciklin
Antibiotic
Brand name Doksiciklin ATC J01AA02 DDD O 0,1g INN doxycycline Pregnancy D Lactation Avoid
Form and Package capsules 5 x 100 mg
INDICATIONS Acute and chronic gastrointestinal, respiratory and urogenital tract, ENT and skin infections, caused by strains susceptible to doxycycline Rickettsial infections (typhus group, Q fever) Chlamydial infections (limphogranuloma venerum, nonspecific urethritis genitalne infections, pneumonia, trachoma, inclusion conjunctivitis) Infections due to borrelia (borreliosis, recurrent fever) Infections due to mycoplasma (pneumonia, tularemia, cholera) As an alternative drug in the treatment of gonorrhoea and syphilis.
J01C J01CA J01CA04
BETA LACTAM ANTIBACTERIALS, PENICILLINS PENICILLINS WITH EXTENDED SPECTRUM amoxicillin
Amoksicilin
antibiotic
Brand name Amoksicilin ATC J01CA04 Form and Package capsules 16 x 250 mg capsules 16 x 500 mg powder for syrup 100 ml (250 mg/5 ml) DDD O1g INN amoxicillin Pregnancy B Lactation Caution
INDICATIONS Amoxicillin is a broad spectrum antibiotic effect, which is used in the treatment of infections (caused by susceptible microorganisms) upper respiratory tract, oral cavity, pharynx, middle ear infections, lower respiratory tract, urinary tract infections (including gonorrhea), gastrointestinal tract (including Salmonella infection), Lyme disease in children, infection of the skin and soft tissue infections, endocarditis prophylaxis, eradication of Helicobacter pylori, as well as in the treatment of other infections caused by microorganisms sensitive to amoxicillin.
J01CE J01CE30
BETA LACTAMASE SENSITIVE PENICILLINS benzylpenicillin, procaine benzylpenicillin
Pancillin
antibiotic
Brand name Pancillin ATC J01CE30 Form and Package lio vial 50 x 800 000 i.u. DDD P 1,6 MIU
INN benzylpenicillin, procaine benzylpenicillin Pregnancy B Lactation Avoid
INDICATIONS PANCILLIN is indicated for the prophylaxis and treatment of infections caused by organisms susceptible to penicillin. * Most commonly used for: - Uncomplicated cases of pneumococcal pneumonia - Streptococcal infections (tonsillitis, scarlet fever, sinusitis) - diphtheria - gonorrhea - syphilis For gonorrhea and syphilis cure only applies when the sensitivity of the pathogen was confirmed. * The prophylactic use before surgery on the head, neck, mouth and on the cardiovascular system.
J01CR02
amoxicillin and clavulanic acid
Panklav
Antibiotic
Brand name Panklav ATC J01CR02 Form and Package Film coated tablets 15 x (250+125) mg Film coated tablets 20 x (500+125) mg powder for oral susp. 100 ml (125+31,25) mg/5 ml powder for oral susp. 100 ml (250+62,5) mg/5 ml DDD O1g INN amoxicillin and clavulanic acid Pregnancy B Lactation
Caution
INDICATIONS Panklav used in the short-term treatment of bacterial infections in cases caused by bacteria that produce beta-lactamase and are resistant to amoxicillin. In other cases, to consider the application of amoxicillin. The combination of amoxicillin and clavulanic acid, betalactamase inhibition has expanded spectrum activity and is recommended in the treatment of:
Infections of the upper-respiratory tract infections (sinusitis, otitis media and recurrent tonsillitis). The most common causes of these infections are Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes. Infection of the lower respiratory tract (especially in cases of acute exacerbation of chronic bronchitis and bronchopneumonia). Common causes of these infections are Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis. - Urogenital tract infections and abdomen, especially cystitis (recurrent or complicated, but excluding prostatitis), septic abortion, pelvic or puerperal sepsis and intraabdominal sepsis. Common causes of these infections were Enterobacteriaceae (mostly Escherichia coli), and Enterobacter species Staphylococcus saprophyticus. - Infections of skin and soft tissue infections (particularly infections and cellulitis after bite animals and humans, as well as severe dental abscesses with cellulitis). Common causes of these infections are Staphylococcus aureus, Streptococcus pyogenes and Bacteroides species. Mixed infections caused by organisms susceptible to amoxicillin, associated with microorganisms that produce beta-lactamase and who are sensitive to Panklav, can be treated with Panklav. In the treatment of such infections should not add some antibiotic resistant to beta-lactamase.
J01CR02 amoxicillin and clavulanic acid
Panklav 2X
Antibiotic INDICATIONS Panklav 2X is indicated for use in the treatment of infections in adults and children: acute bacterial sinusitis (a certified diagnostic) acute inflammation of the middle ear (otitis media) acute exacerbation of chronic bronchitis (a certified diagnostic) community acquired pneumonia cystitis pyelonephritis infections of the skin and soft tissues, particularly cellulitis, animal bites, severe dental abscess with spreading cellulitis bone and joint infections, especially osteomyelitis. It is necessary to take into account official recommendations on the appropriate application of antibacterial drugs.
Brand name Panklav 2X ATC J01CR02 Form and Package Film coated tablets 14 x (875+125) mg powder for oral susp. 70 ml (400+57) mg/5 ml powder for oral susp. 140 ml (400+57) mg/5 ml DDD O1g
INN amoxicillin and clavulanic acid Pregnancy B Lactation Caution
J01D J01DA J01DA01
OTHER BETA LACTAM ANTIBACTERIALS CEPHALOSPORINS cefalexin
Cefaleksin
Antibiotic
Brand name Cefaleksin ATC J01DA01 Form and Package capsules 16 x 250 mg capsules 16 x 500 mg syrup 100 ml (250 mg/5 ml) DDD O2g
INN cephalexin Pregnancy B Lactation Caution
INDICATIONS Cephalexin is indicated for the treatment of infections caused by susceptible bacteria: Infections of the respiratory tract (tonsillitis, pharyngitis, sinusitis, acute and chronic bronchitis, infections of bronchiectasis) Otitis media Infections of the skin, soft tissues, bones and joints Infections of genito-urinary tract (acute prostatitis, cystitis, pyelonephritis) Infection in the oral cavity.
respond to i.v. use of cefuroxime (750 mg) and metronidazole (500 mg per 100 ml) for eight hours. In severe mixed infections J01DC02 cefuroxime may be indicated intravenous cefuroxime in larger doses (1500 mg) and metronidazole (500 mg per 100 ml) for eight hours. In the prophylaxis of postoperative infections (eg colorectal or gynecological surgery) is indicated only a single dose of 1500 mg Antibiotic of cefuroxime and metronidazole (500 mg per 100 ml). If necessary, they can be given two doses of 750 mg of Brand name INN cefuroxime in combination with metronidazole. Nilacef cefuroxime Na Indications include: ATC DDD Pregnancy Respiratory infections (eg, acute and chronic bronchitis, J01DC02 O 0,5 g; P 3 g B bronchiectasis associated with infection, bacterial pneumonia, JKL Form and package Lactation lung abscess, postoperative chest infection) 0321971 inj. (powder for inj.) 1 x750 mg Compatible 0321972 inj. (powder for inj.) 1 x1500 mg Infections of the ear, nose and throat (eg, sinusitis, tonsillitis, pharyngitis) Urinary tract infections (eg, acute and chronic pyelonephritis, INDICATIONS cystitis, asymptomatic bacteriuria) Cefuroxime is a bactericidal antibiotic of cephalosporin group, soft tissue infections (eg, cellulitis, erysipelas, peritonitis and which is resistant to most lactamases and is active in a broad wound infections) spectrum of gram-positive and gram-negative microorganisms. It is used in the treatment of infections before identifying the cause, bone and joint infections (eg, osteomyelitis, septic arthritis) as well as infections caused by microorganisms sensitive to this Gynaecological and obstetric infections (pelvic inflammatory disease) antibiotic. In addition, effective in the prophylaxis of postoperative Gonorrhea (especially if they can not give penicillin) infections in many operations. Cefuroxime may be used as monotherapy or, if necessary, together with aminoglycosides and Other infections, including septicemia and meningitis Surgical prophylaxis (operations of abdomen, pelvis, heart and metronidazole, orally, parenterally or as a suppository. blood vessels, lung, esophageal, orthopedic procedures, in In the case of the presence or suspected presence of mixed which there is an increased risk of infection). aerobic and anaerobic infections (eg, peritonitis, aspiration pneumonia, abscesses of lung, pelvic or brain), or if it is likely to occur (eg colorectal or gynecological surgery) cefuroxime use in combination with metronidazole . Most of these infections will
Nilacef
J01DD02
ceftazidime
Forcas
Antibiotic
Brand name Forcas ATC J01DD02 JKL 0321600 0321601 DDD P4g Form and package inj. 1 x 1000 mg inj. 1 x 500 mg INN ceftazidime Pregnancy B Lactation Compatible
Gastrointestinal, biliary and abdominal infections Infections of bones and joints Dialysis: infections associated with hemodialysis, peritoneal dialysis and continuous ambulatory peritoneal dialysis (CAPD). In meningitis, before the ceftazidime monotherapy, to do antibiogram. Ceftazidime may be used in the treatment of infections with the pathogens resistant to other antibiotics, including aminoglycosides and many cephalosporins. If indicated, can be used in combination with aminoglycosides or other beta-lactam antibiotics, eg. with severe neutropenia or in combination with antianaerobe drugs if Bacteroides fragilis is suspected. Likewise, ceftazidime is indicated in perioperative prophylaxis in transurethral prostatectomy. In vitro combination of ceftazidime and aminoglycosides showed additive effect, and in some strains tested and synergy, which may be of importance in the treatment of patients with febrile neutropenia.
INDICATIONS Ceftazidime is indicated in the treatment of infections caused by a single cause, mixed infections caused by two or more susceptible microorganisms and, generally, in the treatment of serious infections, such as: Respiratory infections Infections of the ear, nose and throat Urinary tract infections Infections of skin and soft tissue
J01DA1
ceftriaxone
Azaran
Antibiotic
Brand name Azaran ATC J01DA13 Form and Package powder for injections 50 x 1000 mg DDD P2g
INN ceftriaxone Pregnancy B Lactation Caution
INDICATIONS Ceftriaxone is indicated for the treatment of the following infections caused by susceptible microorganisms when parenteral therapy is required: Pneumonia Septicemia Meningitis Infections of the bones, skin and soft tissue infections in patients with neutropenia Perioperative prophylaxis of infections associated with surgical procedures. The treatment can be started before receiving confirmation of infectious agents. Adhere to the guidelines for the treatment of certain infections and appropriate antibiotic
J01DE J01DE01
CEPHALOSPORINES IV GENERATION cefepim
Cefim
IV generation cephalosporine
Brand name Cefim ATC J01DE01 DDD 2gP INN cefepim Pregnancy B Lactation
Form and Package
powder for injection or infusion 500 mg Allowed powder for injection or infusion 1000 mg
INDICATIONS Cefim is used in the treatment of moderate to severe and severe infections caused by susceptible microorganisms. Here include: Lower respiratory tract infections including pneumonia and bronchitis Uncomplicated and complicated urinary tract infections, including pyelonephritis Uncomplicated skin and soft tissue Complicated intra-abdominal infections, including peritonitis and biliary tract infections (in combination with metronidazole) Empirical therapy in patients with febrile neutropenia Cefim used to prevent infections in intra-abdominal surgery (in combination with metronidazole).
J01F J01FA J01FA01
MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS MACROLIDES erythromycin
Eritromicin
Antibiotic
Brand name Eritromicin ATC J01FA01 Form and Package Film coated tablets 20 x 250 mg Film coated tablets 20 x 500 mg DDD INN erythromicin-ethylsuccinate Pregnancy
O, P 1 g; O 2 g B Lactation Compatible
INDICATIONS Therapy and prophylaxis of infections caused by bacteria susceptible to erythromycin. upper respiratory infections: tonsillitis, peritonsillar abscess, pharyngitis, laryngitis, sinusitis, bacterial superinfection after influenza and the common cold.
lower respiratory tract infections: tracheitis, acute and chronic bronchitis, pneumonia (lobular pneumonia, bronchopneumonia, primary atypical pneumonia), bronchiectasis, Legionnaires disease. Ear infections: otitis media and external otitis, mastoiditis. Oral infections: gingivitis, Vincent angina. Eye infection: blepharitis. Skin and soft tissue: ulcers and carbunculus, paronichia, abscesses, pustules, impetigo, cellulitis, erysipelas. Gastrointestinal infections: cholecystitis, staphylococcal enterocolitis. Prophylaxis: pre-and post-operative trauma, burns, rheumatic fever. Other infections: osteomyelitis, urethritis, gonorrhea, syphilis, lymphogranuloma venerum, diphtheria, prostatitis, scarlet fever.
J01FA JO1FA09
MACROLIDES clarithromycin
Zymbaktar
Antibiotic
Brand name Zymbaktar ATC J01FA09 DDD 0,5 g O 1gP Form and Package Film coated tablets 14 x 250 mg Film coated tablets 14 x 500 mg Granules for oral susp. 125 mg/100 ml Granules for oral susp. 250 mg/100 ml INN clarithromycin Pregnancy C, Avoid unless no alternative present Lactation Excreted in breast milk. Avoid
INDICATIONS Clarithromycin film-coated tablets are indicated in adults and children older than 12 years. Clarithromycin is indicated for the treatment of infections caused by susceptible micro-organisms. The indications include: Infection of the lower respiratory tract, eg acute and chronic bronchitis and pneumonia. -Infection of the upper respiratory tract, for example, sinusitis and pharyngitis. Clarithromycin is appropriate to begin therapy community acquired infections and it has been shown that in vitro active
against common and atypical respiratory pathogens. Clarithromycin is indicated for the treatment of mild to moderately severe infections of the skin and soft tissues. Clarithromycin is recommended, along with a suppressor of acid secretion omeprazole or lansoprazole in eradicating the bacteria H. pylori in patients with duodenal ulcer. In vitro activity of clarithromycin showed the following organisms: Gram-positive bacteria: Staphylococcus aureus (methicillinsusceptible), Streptococcus pyogenes (Group A beta hemolytic streptococcus), alpha hemolytic streptococci (viridans group); Streptococcus (diplococcus) pneumoniae; Streptococcus agalactiae; Listeria monocytogenes. Gram-negative bacteria: Haemophilus influenzae; Haemophilus parainfluenzae; Moraxella (Branhamella) catarrhalis; Neisseria gonorrhoeae; Legionella pneumophila; Bordetella pertussis; Helicobacter pylori Campylobacter jejuni. Mycoplasma: Mycoplasma pneumoniae; Ureaplasma urealyticum. Other organisms: Chlamydia trachomatis; Mycobacterium avium; Mycobacterium leprae. Anaerobes: Bacteroides fragilis sensitive to macrolides; Clostridium perfringens; Peptococcus species Peptostreptococcus species; Propionibacterium acnes. Clarithromycin is bactericidal against several bacterial strains. Among these organisms are Haemophilus influenzae; Streptococcus pneumoniae; Streptococcus pyogenes; Streptococcus agalactiae; Moraxella (Branhamella) catarrhalis; Neisseria gonorrhoeae; H. pylori and Campylobacter spp. Clarithromycin is more active against H. pylori under conditions of neutral pH than at acidic pH.
J01FA10
azithromycin
Hemomycin
Antibiotic
Brand name Hemomycin ATC DDD J01FA10 O 0,3 g Form and package capsules 6 x 250 mg powder for oral susp. 1 x 20 ml (200 mg/1 ml) film coated tablets 3 x 500 mg powder for oral susp. 1 x 20 ml (100 mg/5 ml) powder for oral susp. 1 x 30 ml (200 mg/5 ml) inf. 500 mg
INN azithromycin Pregnancy B Lactation
Avoid
INDICATIONS Azithromycin is indicated for the treatment of infections caused by susceptible organisms: Upper respiratory tract infections: sinusitis, pharyngitis / tonsillitis (as an alternative first line therapy) lower respiratory tract infections: bacterial bronchitis, community acquired pneumonia, if appropriate oral therapy Acute otitis media Uncomplicated skin and soft tissue (including erythema migrans) uncomplicated urethritis and cervicitis caused by Chlamydia trachomatis Genital ulcer (chancroid, ulcus molle) in men.
J01FF J01FF01
LINCOSAMIDES clindamycin
Klindamicin
Antibiotic
Brand name Klindamicin ATC J01FF01 Form and package inj. 10 x 2 ml/(150 mg/1 ml) DDD O 1,2 g; P 1,8 g
INN clindamycin Pregnancy B Lactation Compatible
INDICATIONS Treatment of serious infections caused by organisms sensitive to clindamycin.
J01G J01GB J01GB03
AMINOGLYCOSIDE ANTIBACTERIALS OTHER AMINOGLYCOSIDES gentamicin
Gentamicin
Antibiotic
Brand name Gentamicin ATC J01GB03 Form and package inj. 10 x 80 mg/2 ml inj. 10 x 120 mg/2 ml DDD P 0,24 g
INN gentamicin Pregnancy D Lactation Caution
INDICATIONS Urinary tract infections (complicated and recidive) Respiratory tract infections Gastro-intestinal tract infections (including peritonitis) Skin infections (including burns) Soft tissue and bone infection Septicemia (neonatal septicemia included) Serious bacterial infections due to unknown cause Mixed infections
J01M QUINOLONE ANTIBACTERIALS J01MA FLUOROQUINOLONES J01MA02 ciprofloxacin
Marocen
Antibiotic
Brand name Marocen ATC DDD J01MA02 O 1 g; P 0,5 g Form and package Film coated tablets 10 x 250 mg film coated tablets 10 x 500 mg inj. 5 x 100 mg/10 ml INN ciprofloxacin Pregnancy C Lactation Avoid
INDICATIONS Ciprofloxacin is indicated for the treatment of the following infections caused by susceptible bacteria. Before initiation of therapy with ciprofloxacin should take into account available information on resistance to ciprofloxacin. Adults Infections of the lower respiratory tract caused by gramnegative bacteria: exacerbation of chronic obstructive pulmonary disease; broncho-pulmonary infections in cystic fibrosis and bronchiectasis; pneumonia Chronic suppurating otitis media Acute exacerbation of chronic sinusitis especially if it is caused by gram-negative bacteria
Urinary tract Infections Gonococcal urethritis and cervicitis epididymis-orchitis including cases caused by the Neisseria gonorrhoeae Pelvic inflammatory disease, including those caused by the Neisseria gonorrhoeae Infections of the genital organs that are thought or known to be caused by the Neisseria gonorrhoeae is very important to take into account the local prevalence of resistance to ciprofloxacin and to confirm susceptibility with appropriate microbiological tests. Gastrointestinal infections (eg travelers diarrhea) Intra-abdominal infections Infections of the skin and soft tissue caused by Gram-negative bacteria Necrotizing (malignant) otitis externa Infections of bones and joints Treatment of infections in patients with neutropenia Prophylaxis of infections in patients with neutropenia Prophylaxis of invasive infections due to Neisseria meningitidis Pulmonary anthrax (after exposure prophylaxis and therapy) Children and adolescents Bronchopulmonary infections in cystic fibrosis caused by Pseudomonas aeruginosa Complicated urinary tract infections and pyelonephritis Pulmonary anthrax (after exposure prophylaxis and therapy) If it is deemed necessary, ciprofloxacin can be used to treat severe infections in children and adolescents. Treatment can start a physician experienced in the treatment of cystic fibrosis and / or severe infections in children and adolescents.
J01MA12
levofloxacin
Forteca
Antibiotic INDICATIONS Levofloxacin is indicated for the treatment of adult patients with mild to moderate infections caused by susceptible bacteria: Acute bacterial sinusitis (adequately diagnosed according to national and /or local guidelines for the treatment of respiratory infections) Acute bacterial exacerbation of chronic bronchitis (adequately diagnosed according to national and /or local guidelines for the treatment of respiratory infections) community acquired pneumonia uncomplicated urinary tract infections Complicated urinary tract infections, including pyelonephritis Chronic bacterial prostatitis Infections of skin and soft tissue Before prescribing levofloxacin to take into account the recommendations of national and /or local guides on the appropriate application of fluoroquinolones.
Brand name Forteca ATC J01MA12 DDD 0,5 g O
INN levofloxacin hemihydrate Pregnancy C Lactation Avoided, it excreted in milk
J01MB OTHER QUINOLONES J01MB04 pipemidic acid
Pipem
Uroantiseptic
Brand name Pipem ATC J01MB04 Form and package capsules 20 x 200 mg DDD O 0,8 g
INN pipemidic acid Pregnancy No data available Lactation Avoid
INDICATIONS Pipemidic acid is a urinary antiseptic used for the treatment of infections caused by microorganisms sensitive to pipemidic acid: Acute and chronic infections of the lower urinary tract, Prevention of recurrent lower urinary tract infection, Vaginal infections
J01X J01XX J01XX08
OTHER ANTIBACTERIALS OTHER ANTIBACTERIALS linezolid
Zenix
Antibiotic
Brand name Zenix ATC J01XX08 Form and package tablets 10 x 600 mg inf. solution 10 x 600 mg DDD O, P 1,2 g INN linezolid Pregnancy C. No data available Lactation Caution No data available
Complicated skin and skin structure infections. Linezolid is to be used only if it is proven or suspected that infection is due to gram-positive bacteria. In patients with infection due to gram-positive and gramnegative bacteria, linezolid can be used only when other therapeutic methods are not available and in combination with drugs for gram-negative bacteria. Before starting treatment with Zenix it is necessary to have information about gram-positive bacteria resistance to antibacterial drugs or to do antibiogram. Linezolid does not effect gram-negative bacteria. If it is proven or suspected that infection is due to gram-positive bacteria as well as gramnegative bacteria, combined treatment with antibacterials that effect gram-negative bacteria is necessary.
INDICATIONS Zenix is indicated in treatment of the following infections caused by susceptible gram-positive bacteria: Nosocomial pneumonia Community-acquired pneumonia
J02 J02A J02AC J02AC01
ANTIMYCOTICS FOR SYSTEMIC USE ANTIMYCOTICS FOR SYSTEMIC USE TRIAZOLE DERIVATIVES fluconazole
Fluconal
Antimycotic
Brand name Fluconal ATC DDD J02AC01 O, P 0,2 g Form and package capsules 7x50mg capsules 1x150mg INN fluconazole Pregnancy C Lactation Excretion in breast milk. It can be used during lactation period only in children with disseminated candidiasis
INDICATIONS Fluconal is indicated for the treatment of the following conditions: Genital candidiasis. Vaginal candidiasis, acute or recurrent. Candida balanitis. It is necessary to consider the treatment of partners. Mucosal candidiasis (oropharyngeal and oesophageal candidiasis, non-invasive bronchopulmonary infections,
Candiduria, mucocutaneous candidiasis and chronic atrophic oral candidiasis (oral thrush). The persons with normal immune systems can be treated, and immunocompromised patients also. Dermatomycosis including tinea pedis, tinea corporis, tinea cruris, tinea versicolor and dermal candidiasis only in those states where there is resistance to first-line therapy or if this infections occur in immunocompromised patients. Systemic candidiasis including candidaemia, disseminated candidiasis and other forms of invasive Candida infections. This refers to the infection of peritoneum, endocardium, lungs and urinary tract. The safest and Candida infections in patients with malignancy, in patients in intensive care, as well as in patients receiving cytotoxic or immunosuppressive therapy. cryptococcal infections, including cryptococcal meningitis and infections of other sites (eg, lung, skin). With Fluconal can treat people with normal immune systems, patients with AIDS, organ transplants and immunosuppresion of other origin. Fluconal can be used as maintenance therapy for relapse prevention of cryptococcal infection in patients with AIDS. Prevention of fungal infections in patients with immunodeficiency, who are at risk of neutropenia after cytotoxic chemotherapy or radiation therapy, including patients with bone marrow transplantation.
Fluconal
Brand name Fluconal ATC J02AC01
antimycotic for systemic use

INN fluconazole DDD O, P 0,2 g Pregnancy C Lactation Excretion in breast milk. It can be used during lactation period only in children with disseminated candidiasis
Form and package inf. solution 2 mg/ml 100 ml
INDICATIONS Fluconazole is indicated in adults for the treatment of: cryptococcal meningitis. coccidioidomycosis. Invasive candidiasis mucosal candidiasis, including oropharyngeal, esophageal candidiasis, candiduria and chronic mucocutaneous candidiasis. Chronic atrophic oral candidiasis (with the use of dentures) if oral hygiene and topical therapy does not demonstrate efficacy. Fluconazole is indicated in adults for the prophylaxis of: The reappearance of cryptococcal meningitis in patients at high risk of recurrence.
Repeated occurrence of oropharyngeal or esopharyngeal candidiasis in patients infected with HIV who are at high risk for relapse. Prophylaxis of Candida infections in patients with prolonged neutropenia (such as patients with hematological malignancies who are undergoing chemotherapy or patients who have had a transplant of hematopoietic stem cells. Fluconazole is indicated in term neonates, infants, children and adolescents under the age of 17 years: Fluconazole is used to treat mucosal candidiasis (oropharyngeal, esophageal), invasive candidiasis, cryptococcal meningitis and prophylaxis of Candida infections in immunocompromised patients. Fluconazole can be used as a preventive therapy of cryptococcal meningitis in children with high risk of recurrence. Therapy can be started before the results of cultures and other laboratory analysis to be known, but, once these results become available, anti-infective therapy should be adjusted to the results obtained. Should be considered official guidance on the appropriate use of antifungal drugs.
L L01CD02
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS docetaxel
Docetaxel HF
Antineoplastic
Brand name Docetaxel HF ATC L01CD02 Form and Package Concentrate and solvent for solution infusion, 20 mg/0,5 ml Concentrate and solvent for solution infusion, 80 mg/2 ml DDD INN docetaxel Pregnancy D Lactation Breastfeeding is not recommended
INDICATIONS Breast cancer Docetaxel in combination with doxorubicin and cyclophosphamide is indicated for the adjuvant treatment of patients with operable node positive breast cancer. Docetaxel in combination with doxorubicin is indicated for the treatment of patients with locally advanced or metastatic breast cancer who have not previously received treatment with cytotoxic drugs to treat this disease. Docetaxel as a single agent, is indicated for the treatment of patients with locally advanced or metastatic breast cancer after failure of prior cytotoxic therapy applied. Previous chemotherapy should include anthracycline or alkylation agent.
Docetaxel in combination with trastuzumab is indicated for the treatment of patients with metastatic breast cancer whose tumors over-express HER2, who had not previously received chemotherapy for metastatic disease. Docetaxel in combination with capecitabine, is indicated for the treatment of patients with locally advanced or metastatic breast cancer after failure of cytotoxic chemotherapy. Previous therapy should include anthracycline. Non-small cell lung cancer Docetaxel is indicated for the treatment of patients with locally advanced or metastatic non small cell lung cancer after failure of prior chemotherapy. In combination with cisplatin, docetaxel is indicated for the treatment of patients with unresectable, locally advanced or metastatic non-small cell lung cancer, in patients who have not previously received chemotherapy for this disease. Prostate Cancer Docetaxel in combination with prednisone or prednisolone is indicated for the treatment of patients with hormone-refractory metastatic prostate cancer. Adenocarcinoma of the stomach Docetaxel in combination with cisplatin and 5-fluorouracil is indicated for the treatment of patients with metastatic gastric adenocarcinoma, including adenocarcinoma of the gastroesophageal coupling, which had not previously received chemotherapy for metastatic disease. Head and neck cancers Docetaxel, in combination with cisplatin and 5-fluorouracil is indicated for the induction treatment of patients with locally advanced squamous cell carcinoma of the head and neck.
L01XA03
oxaliplatin
Oxaliplatin HF
Antineoplastic
Brand name Oxaliplatin HF ATC L01XA03 Form and package Powder for solution infusion 50 mg Powder for solution infusion 100 mg DDD
INN oxaliplatin Pregnancy D Lactation Contraindicated
INDICATIONS Oxaliplatin in combination with 5-fluorouracil (5-FU) and folinic acid (FA) is indicated for: - Adjuvant treatment of colorectal cancer in clinical stage III (Dukes C) after radical surgery; - Treatment of metastatic colorectal cancer.
L02AB01
megestrol acetate
OTentika
Progestagen
Brand name OTentika ATC L02AB01 DDD 0,16 g O
INN megestrol acetate Pregnancy C Lactation Avoided
INDICATIONS OTentika used to treat anorexia or weight loss that is caused by malignant disease (cachexia), or acquired immunodeficiency syndrome (AIDS) patients of both sexes.
Form and package oral suspension 40 mg/ml, 240 ml
L02BG03
anastrozole
Altravesa
Selective aromatase inhibitor
Brand name Altravesa ATC L02BG03 DDD O 1 mg
INN anastrozole Pregnancy X Lactation Contraindicated
INDICATIONS Treatment of hormone receptor-positive advanced breast cancer in postmenopausal women Adjuvant therapy of hormone receptor-positive early invasive breast cancer in postmenopausal women Adjuvant treatment of early invasive hormone receptor positive breast cancer in postmenopausal women who received adjuvant tamoxifen therapy 2 to 3 years
Form and package F.c.-tbl. 28 x 1 mg
M M01 M01A M01AB M01AB05
MUSCULO-SKELETAL SYSTEM ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS ACETIC ACID DERIVATIVES AND RELATED SUBSTANCES diclofenac
Diclofenac Rapten Duo Rapten K

Brand name Diclofenac Rapten Duo Rapten K ATC M01AB05
non-steroid antiinflammatory drug, analgesic

INN diclofenac sodium DDD O,P,R 0,1 g diclofenac potassium Pregnancy C (D in 3rd trimester and in time of baby delivery) Lactation
INDICATIONS Inflammatory and degenerative articular and extraarticular rheumatism (rheumatoid arthritis, osteorthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, arthrosis and spondiloarthrosis, spondylosis, periarthritis, tendovaginitis, fibrositis, myositis) Primary dysmenorrhea Acute uric arthritis Renal and biliar colic (parenteral use)
Form and package Film coated tablets 30 x 50 mg retard tablets 20 x 100 mg inj. 5 x 75 mg / 3 ml supp. 10 x 25 mg Caution supp. 10 x 50 mg tablets 30 x 75 mg dragee 10 x 50 mg
Zodol
NSAID, analgesic
Brand name Zodol ATC M01AB15 DDD O, P 0,03 g
INN ketorolac Pregnancy C (D in 3rd trimester) Lactation Avoid
INDICATIONS Zodol is indicated for short-term treatment of moderate and severe acute pain and may replace opioid analgesics (postoperative pain, renal colic, orthopedic trauma, cancer related pain). Ketorolac is not used for the treatment of chronic pain conditions.
Form and package F.c.-tbl. 10 x10 mg inj..5x30 mg/ml
M04 M04A M04AA M04AA01
ANTIGOUT PREPARATIONS ANTIGOUT PREPARATIONS PREPARATIONS INHIBITING URIC ACID PRODUCTION allopurinol Clinical conditions which may give rise to the formation of deposits of urate and uric acid are idiopathic gout, urolithiasis, acute uricosuric nephropathy, neoplasms and myeloproliferative diseases with intense cellular metabolic turnover, in which high levels of uric acid occur spontaneously or after cytotoxic therapy, certain enzyme disorders lead to increased production of uric acid (a disorder hypoxanthine-guanine phosphoribosiltransferase, including Lesch-Nyhan syndrome, a disorder of glucose-6phosphatase involvement of the accumulation of glycogen synthase phosphoribosilpyrophosphate disorder, disorder phosphoribosilpyrophosphate amidotransferase, adenine phosphoribosiltransferase disorder). Allopurinol is used to treat 2,8-dihydroxiadenine (2,8DHA) renal calculi due to decreased activity of adenine phosphoribosiltransferase. Allopurinol is used to treat re-mixed oxalate renal calculi in the presence of hyperuricosuria in cases where diet, increased fluid intake, and similar measures have no effect.
Alopurinol
Brand name Alopurinol ATC M04AA01 Form and package tablets 40 x 100 mg
antiuric (uricostatic)
INN allopurinol DDD O, P 0,4 g Pregnancy C Lactation Avoid
INDICATIONS Allopurinol is used for the reduction of the urate and uric acid in states that already have deposits of urate and uric acid (gout, nephrolithiasis), or there is the risk of these deposits (malignancy therapy that could potentially cause acute uricosuric nephropathy).
M05BA04 alendronic acid (in form of sodium salt)
Bonap
Bisphosphonate
Brand name Bonap ATC M05BA04 JKL 1059079 DDD 10 mg O Form and package tablets 4 x 70 mg
INN Alendronic acid Pregnancy C Lactation Avoided
INDICATIONS Post-menopausal osteoporosis (alendronate reduces the risk of vertebral and hip fractures).
N N02 N02A N02AX N02AX02
NERVOUS SYSTEM ANALGESICS OPIOIDS OTHER OPIOIDS tramadol
Trodon
opioid analgesic
Brand name Trodon ATC DDD N02AX02 O,P 0,3g Form and package capsules 20 x 50 mg injections 5 x 50 mg/ ml injections 5 x 100 mg/ 2 ml film coated retard tablets 10 x 100 mg film coated retard tablets 10 x 200 mg INN tramadol Pregnancy C Lactation Avoid
INDICATIONS Treatment of moderate to severe pain.
N02CC03 zolmitriptan
Zolmitriptan
anti-migraine drug
Trade mark Zolmitriptan ATC DDD N02CC03 O, 2,5 mg Form and package Oral dispersible tablets 3 x 2,5 mg Oral dispersible tablets 6 x 5 mg
INN zolmitriptan Pregnancy C Lactation Caution
INDICATIONS Zolmitriptan is indicated for acute treatment of migrain with or without aura.
N03 N03A
ANTIEPILEPTICS ANTIEPILEPTICS
Eftil Eftil retard

antiepileptic INDICATIONS Eftil retard is used in children and adults as monotherapy or in combination with other antiepileptic drugs in the treatment of: Generalized seizures: clonic and tonic seizures, tonicclonic seizures (grand mal epilepsy), absence seizures (petit mal seizures) and myoclonic seizures or atonic and Lennox-Gastaut syndrome. Partial epilepsy: partial seizures with or without secondary generalization.
Brand name Eftil Eftil retard ATC N03AG01 DDD O, P, R 1,5 g
INN Valproic acid + sodium valproate Pregnancy D Lactation Caution
Form and package syrup 150 ml/5,764 g retard film tablets 30 x(145 + 333) mg
N03AX09 lamotrigin
Solaban
Antiepileptic
Brand name
Solaban
ATC N03AX09
DDD O 0,3 g
Form and package Tablets for oral suspen. 30 x 5 mg Tablets for oral suspen. 30 x 25 mg Tablets for oral suspen. 30 x 50 mg Tablets for oral suspen. 30 x 100 mg
INN Lamotrigin Pregnancy C -All antiepileptic drugs are teratogenic but the benefit of application is greater than the risk for the fetus. Lactation Present in milk, potentially toxic to children, avoiding breastfeeding
As a complementary therapy of epilepsy: partial seizures, generalized seizures (attacks the primary and secondary tonic-clonic seizures) and seizures in the Lennox-Gastaut syndrome in case of failure of treatment with other antiepileptic drugs. Children older than 2 years: As a complementary therapy of epilepsy: partial seizures and seizures in the Lennox-Gastaut syndrome. 2) Bipolar affective disorder: Adults (over 18) The prevention of depressive episodes in patients with bipolar affective disorder. Suggested use: For the treatment administered by a neurologist, pediatric neurologist or a psychiatrist or physician who knows the treatment of epilepsy and is especially qualified to treat the mentally handicapped patients, the treatment in the department of neurology, psychiatry and mental disorders.
INDICATIONS Lamotrigine is indicated in the treatment of: 1) epilepsy: Adults and adolescents: In the monotherapy epilepsy: partial seizures and generalized seizures (attacks the primary and secondary tonic-clonic seizures)
N04 ANTI-PARKINSON DRUGS NO4BC DOPAMINE AGONISTS NO4BC05 pramipexole
Panarak
Antiparkinsonic
Brand name Panarak ATC N04BC05 DDD O, 2,5 mg
INN pramipexole Pregnancy C Lactation Avoided
Form and package 30 tablets x 0,18 mg 30 tablets x 0,7 mg
INDICATIONS Pramipexol is indicated in adults for the treatment of signs and symptoms of idiopathic Parkinsons disease as monotherapy (without levodopa) or in combination with levodopa, ie. throughout the period of the disease until the late stages when the effect of levodopa begins to deteriorate or become unstable, leading to fluctuations of the therapeutic effect (end of dose phenomenon or on-off fluctuations). Pramipexol is indicated in adults for the symptomatic treatment of moderate to severe idiopathic restless legs syndrome in doses of less than 0.54 mg pramipexol base (0.75 mg pramipexol salt)
N05 Psycholeptics n05AH dIAZEPINs, OxAZEPINS and ThIAZEPINs N05AH03 olanzapine
Treana
Antipsychotic
Brand name Treana ATC N05AH03 DDD O, P 10 mg
INN olanzapine Pregnancy C Studies have shown toxic effects on the fetus Lactation Avoided, it excreted in milk
Form and package Film tablets 30 x 5 mg Film tablets 30 x 10 mg
INDICATIONS Olanzapine is primarily used to treat schizophrenia. In patients who achieved a good initial response to therapy, olanzapine has proven effective in maintenance therapy and control of symptoms of schizophrenia. Olanzapine is also indicated in the treatment of moderate to severe episodes of mania. In patients with bipolar disorder who have shown good initial response to therapy, during manic episodes, olanzapine is used to prevent recurrence of manic phase of illness.
NO5AX N05AX08
OTHER ANTIPSYHOTICS risperidone
Risperidon
Antipsychotic
Brand name Risperidon ATC DDD N05AX08 O 5 mg Form and package film tablets 20 x 1 mg film tablets 20 x 2 mg film tablets 20 x 3 mg film tablets 20 x 4 mg INN risperidon Pregnancy C applied only if the potential benefit outweighs the risk Lactation avoid it, no reliable data
INDICATIONS Risperidone is indicated for the treatment of a wide spectrum of patients with schizophrenia, including the first episode psychoses, acute schizophrenic exacerbations, chronic schizophrenia and other psychotic states with prominent positive symptoms (such as hallucinations, delusions, thought disorders, hostility, suspiciousness) and / or negative symptoms (indifference, emotional and social withdrawal, the scarcity of speech). Risperidone also facilitates and affective symptoms associated with schizophrenia (depression, guilt, anxiety).
Risperidone is effective for maintenance therapy in patients who have responded to the initial use of risperidone. Risperidone-monotherapy is indicated for the short treatment of manic or mixed episodes associated with bipolar disorder. Combination therapy-concomitant use with lithium or valproic acid is indicated for the short treatment of manic or mixed episodes associated with bipolar disorder, manifesting itself as elevated mood, euphoric or irritable, agitation, grandiosity, exaggerated self-esteem, decreased need for sleep, rapid speech, accelerated thoughts, reduced attention or judgment, including highly active or hostile behavior. Risperidone is indicated for the treatment of severe behavioral disorders in patients with dementia, such as aggressiveness (the verbal performances, as well as in psychiatric manifestations), disturbances of body movement (agitation, movements without goal) or psychotic symptoms that lead patients to a state of suffering, uncertainty themselves and the potential dangers of self-harm. Such patients should be monitored carefully and use the drug Risperidone continue only if the benefit is greater than the risk to the patient. Risperidone is also indicated as an adjuvant therapy to mood stabilizers in treating acute manic episodes in bipolar disorder. Risperidone is indicated in the treatment disruptive behavioral disorders in adults with limited social, academic and work functioning, and which are expressed in behavioral disorders such as aggressiveness, impulsiveness and self-mutilation.
N05B ANXIOLYTICS N05BA BENZODIAZEPINE DERIVATIVES N05BA01 diazepam
Diazepam
Anxiolytic
Brand name Diazepam ATC N05BA01 Form and package tablets 30 x 2 mg tablets 30 x 5 mg tablets 30 x 10 mg DDD O 0,01 g
INN diazepam Pregnancy D Lactation Avoid
INDICATIONS Anxiety states (endogenous or general anxiety due to social conflicts). Insomnia due to anxiety (benzodiazepines are indicated for the treatment of insomnia only in severe cases when the condition interferes with normal functioning and performance of daily activities). acute alcohol abstinence syndrome. Preparation for endoscopic examination and surgical procedures. muscle spasms (including spasms in cerebral spasticity) and the treatment of epilepsy. Night fears and somnambulism in children.
N05BA06 lorazepam
Lorazepam
Anxiolytic
Brand name Lorazepam ATC N05BA06 Form and package tablets 30 x 1 mg tablets 20 x 2,5 mg DDD O 0,0025 g
INN lorazepam Pregnancy D Lactation Avoid
INDICATIONS Lorazepam is indicated: for short-term treatment of anxiety conditions that lead to disability, including anxiety associated with psychosomatic, organic or psychotic illness for short-term treatment of insomnia (sleeplessness) associated with anxiety in premedication before surgery or more extensive dental procedures
N05BA08 bromazepam
Bromazepam
Anxiolytic
Brand name Bromazepam ATC N05BA08 Form and package tablets 30 x 1,5 mg tablets 30 x 3 mg tablets 30 x 6 mg DDD O 0,01 g
INN bromazepam Pregnancy D Lactation Avoid
INDICATIONS Treatment of anxiety. The drug is designed to treat serious disorders that interfere with their daily activities and create serious problems for the patient.
N05BA11 prazepam
Demetrin
Anxiolytic
Brand name Demetrin ATC N05BA11 Form and package tablets 20 x 10 mg DDD O 0,03 g
INN prazepam Pregnancy D Lactation Avoid
INDICATIONS Prazepam is indicated in the treatment of anxiety disorders
N05C N05CF02
HYPNOTICS AND SEDATIVES zolpidem
Belbien
Short-acting hypnotic
Brand name Belbien ATC N05CF02 DDD 10 mg O
INN zolpidem Pregnancy B-applied only if necessary Lactation low concentrations present in milk, avoid it
Form and package film tablets 20 x 10 mg
INDICATIONS Short-term treatment of insomnia. Benzodiazepines and related drugs benzodiazepines are indicated only for severe disorders that deplete or incapacitate the patient
N06AB SELECTIVE SEROTONIN REUPTAKE INHIBITORS N06AB03 fluoxetine
Flunisan
Antidepressive
Brand name Flunisan ATC N06AB03 Form and package tablets 30 x 20 mg DDD O 0,02 g INN fluoxetine Pregnancy B Lactation Avoid
INDICATIONS Adults Major depressive episodes Obsessive Compulsive Disorders Bulimia nervosa: Flunisan is indicated as a supplement to psychotherapy to reduce food intake and increased bowel movements. Children and adolescents aged 8 and over Moderate to severe, major depressive episode, if there is no improvement after 4-6 sessions depression psychotherapy. Antidepressant therapy in children and young adults with moderate and severe depression should always be combined with psychosocial therapy.
N06AB06 sertraline
Sidata
Antidepressive
Brand name Sidata ATC N06AB06 DDD O 50 mg
INN sertraline Pregnancy X Lactation contraindicated
Form and package Film coated tablets 28 x 50 mg Film coated tablets 28 x 100 mg
INDICATIONS The use of SIDATA film-coated tablet is indicated in the following cases: treatment of symptoms of depression, including depression accompanied by anxiety symptoms. After a satisfactory therapeutic response, continuation sertraline treatment efficiency is achieved in the
prevention of initial episodes of depression relapse or re-occurrence of depressive episodes, including the associated symptoms of anxiety. treatment of obsessive compulsive disorder. After a satisfactory therapeutic response, efficiency, safety and tolerability of sertraline application is held up to 2 years of therapy for this disorder. treatment of panic disorder, with or without agoraphobia. treatment of social phobia. Upon satisfactory treatment response, continuation with sertraline therapy achieves efficiency in preventing relapse of initial episodes of social phobia. treatment of post-traumatic stress syndrome. treatment of obsessive compulsive disorder in children older than 6 years.
N06AB10 escitalopram
Lata
Antidepressive
Brand name Lata ATC N06AB10 DDD O, 10 mg
INN escitalopram Pregnancy C Lactation Excreted in milk, avoid it
Form and package film tablets 28 x10 mg
INDICATIONS Escitalopram is used to treat: major depressive episodes panic disorder with or without agoraphobia Social phobia Obsessive-Compulsive Disorder
N06D DRUGS FOR DEMENTION THERAPY N06DA ANTICHOLINERGICS N06DA02 donepezil chloride
Tregona
Drug for demention therapy
Brand name Tregona ATC N06DA02 DDD O 7,5 mg
INN donepezil Pregnancy C-Studies have shown toxic effects on the fetus Lactation Avoid
INDIKACIJE Symptomatic treatment of mild to moderate dementia of the Alzheimer type.
N07 N07B N07BC N07BC02
OTHER NERVOUS SYSTEM DRUGS DRUGS USED IN ADDICTION DISORDERS DRUGS USED IN OPIOID DEPENDENCE methadone
Metadon
Brand name Metadon ATC N07BC02
synthetic narcotic analgesic
INN methadone DDD O, P 0,025 g Pregnancy C Lactation Caution
INDICATIONS Methadone is used to treat opiate addiction, as a means of preventing the appearance of abstinence syndrome.
Form and package drops 1 x 10 ml (10 mg/ ml)
R R R03 R03AC12
RESPIRATORY SYSTEM DRUGS FOR TRETAMENT OF RESPIRATORY DISEASES drugs used in obstructive lung disease salmeterole xinafoate
Serevent Inhaler CFC-Free

Antiasthmatic
Brand name Serevent Inhaler CFC-Free ATC R03AC12 Form and package DDD O 100 mcg INN salmeterole xinafoate Pregnancy C Lactation
inhaler with a pressurized dispenser, 120x25 No data g/dose
INDICATIONS Regular additional symptomatic treatment of reversible airways obstruction in patients with asthma, including patients with nighttime symptoms, which are not adequately controlled with inhaled corticosteroids in accordance with current therapeutic guides. Serevent Inhaler CFC-Free is used in the treatment of chronic obstructive pulmonary disease (COPD) in the prevention of exercise-induced asthma attacks.
R03B Other drugs used in obstructive lung disease, for inhalation R03BA Glucocorticoids R03BA01 beclomethasone dipropionate
Becloforte CFC-Free Inhaler

antiasthmatic
Brand name Becloforte CFC-Free Inhaler DDD ATC R03BA01 800 mcg Form and package inhaler with a pressurized dispenser, 1 x 200 dose (250 g/1 dose) INN beclomethasone dipropionate Pregnancy C Lactation No data
INDICATIONS Severe asthma is a disease that can be fatal and requires regular medical monitoring. Patients with severe asthma have constant symptoms and frequent exacerbations, with limited lung capacity and values of peak expiratory flow (PEF), less than 60% predicted baseline values with a variation greater than 30%, often do not return to normal after the use of bronchodilators. These patients required high doses of inhaled or oral corticosteroid therapy. Sudden worsening of symptoms may require increased doses of corticosteroids should be given under medical supervision.
Adults Prophylaxis in: Mild asthma (PEF values above 80% predicted baseline values, with variations of less than 20%) patients who occasionally require symptomatic treatment of asthma with bronchodilators. Moderate asthma (PEF values 60-80% predicted basal values, ranging from 20-30%) patients who require regular use of drugs to treat asthma and patients with unstable asthma is getting worse despite the implementation of prophylactic therapy or bronchodilator alone. Asthma (PEF values below 60% predicted baseline values, with variations of more than 30%) patients with severe chronic asthma. Children All children that are needed drugs for the prevention of asthma.
R03BA05
fluticasone propionate
Flixotide
antiasthmatic
Brand name Flixotide ATC R03BA05 Form and package DDD 0,6 mg
INN fluticasone propionate Pregnancy C Lactation
suspension for inhalation under pressure;50 No data mcg/dose; pressurized container, 1x120 dose suspension for inhalation under pressure; 125 mcg/ dose; pressurized container, 1x60 dose suspension for inhalation under pressure; 250 mcg/ dose; pressurized container, 1x60 dose
INDICATIONS Fluticasone propionate applied with inhalation provides prophylactic treatment of asthma. Adults: Mild asthma: patients who on a regular daily basis require intermittent bronchodilation therapy. Moderately severe asthma: patients with unstable asthma or asthma that worsens despite application prophylactic therapy or bronchodilator alone. Severe asthma: Patients with severe chronic asthma and those who are dependent on systemic corticosteroids applied to adequately control symptoms. Upon the introduction of fluticasone propionate inhalation, many of these patients can significantly reduce or eliminate the need for oral corticosteroids.
R06 R06A R06AX R06AX13
ANTIHISTAMINES FOR SYSTEMIC USE ANTIHISTAMINES FOR SYSTEMIC USE OTHER ANTIHISTAMINES FOR SYSTEMIC USE loratadine
Pressing
Brand name Pressing ATC R06AX13
non-sedating antihistamines
INN loratadine DDD O 0,01 g Pregnancy B Lactation Caution with higher doses
Form and package eff. tablets 10 x 10 mg tablets 10 x 10 mg syrup 1 x 120 ml (5 mg/5 ml)
INDICATIONS Seasonal allergic rhinits Allergic conjunctivitis Non-seasonal chronic idiopatic rhinits Chronic urticaria and other allergic dermatosis Additional therapy in treatment of bronchial asthma
S S01 S01A S01AA S01AA01
SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFECTIVES ANTIBIOTICS chloramphenicol
Hloramkol
Antibiotic
Brand name Hloramkol ATC S01AA01 Form and package eye ointment 1 x 5 g 1 % 0,5% eye drops, solution DDD INN chloramphenicol Pregnancy C Lactation Caution
INDICATIONS Hloramkol eye ointment 1% is used for the treatment of anterior segment of eye infections (caused by bacteria that are sensitive to chloramphenicol, when other antibiotics have no effect or are contraindicated), such as: blepharitis and blepharoconjunctivitis Bacterial conjunctivitis Bacterial keratitis expository, neuroparalitic and neurotrophic keratitis in the case of secondary bacterial infections Hloramkol eye drops are applied for treatment
Acute bacterial conjunctivitis S01AA11 gentamicin
Gentokulin
Antibiotic
Brand name Gentokulin ATC S01AA11 Form and package eye drops 10 ml 0,3 % DDD INN gentamicin Pregnancy C Lactation Avoid
INDICATIONS Gentokulin is intended to: treatment of superficial eye infections and ear infections caused by susceptible microorganisms for the prophylaxis of infections in trauma to the eye or ear.
S01AX OTHER ANTIINFECTIVES S01AX13 ciprofloxacin
Marocen 0,3%
eye drops
Brand name Marocen ATC S01AX13 Form and package eye drops 1 x 5 ml 0,3% DDD INN ciprofloxacin Pregnancy C Lactation Avoid
INDICATIONS Ciprofloxacin is indicated for the treatment of corneal ulcers and superficial infection of the eye and adnexa, caused by susceptible microorganisms. It is necessary to keep the official guide on the rational use of antibiotic.
S01B S01BA S01BA04
ANTIINFLAMMATORY AGENTS CORTICOSTEROIDS, PLAIN prednisolone
Oftalmol
Corticosteroid
Brand name Oftalmol ATC S01BA04 Form and package eye drops 5 ml 0,5 % DDD INN prednisolone Pregnancy B Lactation Compatible
INDICATIONS Oftalmol is intended for the treatment of inflammation of the anterior segment of the eye without the presence of bacterial, viral or fungal infections: blepharitis, conjunctivitis, keratitis, keratoconjunctivitis, uveitis.
S01C Corticosteroids and anti-infectives in combination S01CA Corticosteroids and anti-infectives in combination S01CA01 dexamethasone, neomycin
Neodeksacin
eye drops
Brand name Neodeksacin ATC S01CA01 Form and package eye drops 10 ml (0,5 % + 0,1) DDD INN dexamethasone, neomycin Pregnancy C Lactation Avoid
INDICATIONS Neodeksacin used in conditions that require corticosteroid therapy, such as inflammation of the eye, bacterial infection and the presence of risk of bacterial eye infections. Neodeksacin is indicated in the following conditions: Inflammation of the anterior segment of the eye conjunctivitis Inflammation of the cornea
Chronic anterior uveitis Corneal injury (burns resulting from the effects of chemical, radiation or thermal means, or penetration of foreign bodies). The combined use of anti-infective component of the drug is indicated in case of high risk or in situations which are expected to bacterial superinfection of the eye. Anti-infective component of this drug is active according to the following bacterial strains: Staphylococcus aureus Escherichia coli Haemophilus influenzae Klebsiella / species Neisseria species Neodeksacin not provide adequate protection against the following microorganisms: Pseudomonas aeruginosa Serratia marcescens Streptococcus spp. (including Streptococcus pneumoniae)
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS S01EB PARASYMPATHOMIMETICS S01EB01 pilocarpine
Miokarpin
miotic
Brand name Miokarpin ATC S01EB01 Form and package eye drops 1 x 10 ml 2% DDD LOC 0,4 ml INN pilocarpine Pregnancy C Lactation Caution
INDICATIONS Miokarpin as miotic applied in the treatment of: reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension acute closed angle glaucoma Prevention of postoperative elevated intraocular pressure associated with the laser operation to induce miosis.
S01EE S01EE01
Prostaglandin analogues latanoprost
Visus
latanoprost
Brand name Visus ATC S01EE01 Form and package Eye drops, 50 g/ml DDD
INN latanoprost Pregnancy C Lactation Caution
INDICATIONS Reduction of elevated intraocular pressure in patients with open-angle glaucoma and intraocular hypertension
S01G DECONGESTANTS AND ANTIALLERGICS S01GA SYMPATHOMIMETICS USED AS DECONGESTANTS S01GA01 naphazoline
Hemokulin
Vasoconstrictor
Brand name Hemokulin ATC S01GA01 Form and Package eye drops 10 ml 0,03 % DDD
INN naphazoline Pregnancy C Lactation Caution
INDICATIONS Hemokulin, eye drops are used for temporary symptomatic remove redness caused by minor irritation.
S01GA02
tetryzoline
Montevizin
Vasoconstrictor
Brand name Montevizin ATC S01GA02 Form and Package eye drops 10 ml 0,05 % eye drops 15 ml 0,05 % DDD
INN tetryzoline Pregnancy C Lactation Avoid
INDICATIONS Hyperemia and / or edema of the conjunctiva caused by a variety of non-specific causes, such as tonometry, placing and fitting of contact lenses, dust, smoke, smog, sun, cold, wind, allergies, swimming, reading, driving, watching television, etc.
DRUGS SOLD WITHOUT A PRESCRIPTION (OTC)
A A01 A01A A01AB A01AB12
ALIMENTARY TRACT & METABOLISM DENTAL PREPARATIONS DENTAL PREPARATIONS Anti-infectives and antiseptics for local therapy of oral cavity hexetidine
Hexoral
INDICATIONS Hexetidine as a local antiseptic is recommended for the treatment of superficial oropharyngeal infections, including ulcers and their prevention (eg, recurrent aphthous ulcers). It helps in the prevention and treatment of gingivitis. It is also used for preoperative performance of dental and surgical procedures in the oral cavity. Also, the use of heksetidina recommended for bad breath from the mouth (foetor ex ore).
Brand name Hexoral ATC A01AB12 Form and Package Sol.for mouth rinsing 200 ml DDD
Generic name hexetidine Pregnancy
Breastfeeding
A02 A02A A02AD05
DRUGS FOR ACID RELATED DISORDERS ANTACIDS Aluminium magnesium silicate hydrate
Gelusil Lac
Antacid
Brand name Gelusil Lac ATC A02AD05 Form and package Tbl. 40 x 500 mg DDD
INN Aluminium magnesium silicate hydrate Pregnancy No data Lactation Excreted into human breast milk. Problems have not been documented in humans.
INDICATIONS Relieve the symptoms of hyperacidity.
A06 A06A A06AB A06AB02
DRUGS FOR CONSTIPATION Drugs for constipation Contact laxatives bisacodyl
Panlax
Contact laxative
Brand name Panlax ATC A06AB02 DDD O, R 10 mg
INN bisacodyl Pregnancy B Lactation
INDICATIONS Short-term symptomatic treatment of constipation. As recommended by physicians to prepare for radiology, diagnostic and surgical procedures that require the bowel emptying.
Form and package
gastroresistant tablets 6 x 10 mg Although not excreted into breast milk, suppositories 6 x 10 mg it's not recommended in breast feeding
A07 A07A A07AA A07AA02
ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS INTESTINAL ANTIINFECTIVES Antibiotics nystatin
Nystatin
Antimycotic
Brand name Nystatin ATC A07AA02 DDD O 1,5 MU
INN nystatin Pregnancy C Lactation Not excreted into milk.
INDICATIONS Nystatin powder for oral suspension is used in the prevention and treatment of fungal infections of the mouth, esophagus and intestinal tract caused by fungi of the genus Candida spp. It is used in the prevention of oral candidiasis in newborns whose mothers had vaginal candidiasis. NYSTATIN tablets are intended for the treatment of gastrointestinal candidiasis.
Form and package 10 coated tablets x 500.000 i.u. 24 ml oral susp. 100.000 i.u/ml
A11 VITAMINS A11H OTHER PLAIN VITAMIN PREPARATIONS A11HA OTHER PLAIN VITAMIN PREPARATIONS A11HA30 dexpanthenol
Panthenol
Vitamin
Brand name Panthenol ATC A11HA30 Form and Package lozenges 20 x 120 mg DDD
Generic name dexpanthenol Pregnancy No data available Breastfeeding No data available
INDICATIONS Relieve symptoms of Inflammation of oral mucosa, throat, tongue and gingiva (stomatitis, aphtous ulcers, glossitis, pharyngitis, laryngitis).
B B01A B01AC B01AC06
BLOOD AND BLOOD FORMING ORGANS ANTITHROMBOTIC DRUGS INHIBITORS OF PLATELET AGGREGATION, EXCL. HEPARIN acetylsalicylic acid
Midol 100
inhibitor of platelet aggregation
Brand name Midol 100 ATC B01AC06 Form and Package Tablets 20 x 100 mg DDD O3g
Generic name acetylsalicylic acid Pregnancy C (1,2) D (3) Breastfeeding Avoid usage during breastfeeding. Possible appearance of Rey syndrome. Frequent usage of high doses can damage thrombocyte function and cause hypoprothrombinemia at breastfed infant.
INDICATIONS Acetylsalicylic acid tablets are indicated for use in the following cases, based on their properties of inhibition of platelet aggregation: To reduce the risk of mortality in patients with suspected acute myocardial infarction;
To reduce the risk of morbidity and mortality in patients who have had previously a myocardial infarction; For secondary prevention of stroke; To reduce the risk of transient ischemic attack (TIA) and stroke in patients suffering from TIA To reduce the risk of morbidity and death in patients with stable and unstable angina pectoris; For the prevention of thromboembolism after surgery or vascular surgery, for example. PTCA, CABG, carotidendarterectomy, arteriovenous shunts in dialysis patients; For prophylaxis of deep vein thrombosis and pulmonary embolism after prolonged immobilization, such as after a major surgical procedures; To reduce the risk of first myocardial infarction in people with risk factors for development of cardiovascular disease, for example diabetes mellitus, hyperlipidemia, hypertension, obesity, smoking and age.
C C05 C05A C05AA C05AA04
CARDIOVASCULAR SYSTEM VASOPROTECTIVES AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE CORTICOSTEROIDS heparin, prednisolone, polidocanol
Hepathrombin H
antihemorrhoidal preparation Brand name Hepathrombin H ATC C05AA04 Form and Package DDD INN heparin, prednisolone, polidocanol Pregnancy C Lactation INDICATIONS In the symptomatic treatment of hemorrhoids and itching in the perianal region in the short period of time.
ointment 20 g (65 i.u.+2,233 mg+30 mg)/g No excretion into breast suppositories 10 x (120 i.u.+1,675 mg+30 mg) milk, save use during breastfeeding.
C05 VASOPROTECTIVES C05B ANTIVARICOSE THERAPY C05BA HEPARINS OR HEPARINOIDS FOR TOPICAL USE C05BA53 heparin, combinations
Hepathrombin
antivaricose therapy
Brand name Hepathrombin ATC C05BA53 Form and Package gel 30000 40 g cream 30000 40 g gel 50000 40 g cream 50000 40 g DDD
INN heparin, dexpanthenol, alantoin Pregnancy C Lactation No excretion into breast milk, save use during breastfeeding.
INDICATIONS Surface thrombophlebitis Relief of symptoms in superficial bruising and hematoma
C05 C05B C05BA C05BA53
VASOPROTECTIVES ANTIVARICOSE THERAPY HEPARINS OR HEPARINOIDS FOR TOPICAL USE heparin, combinations
Sinedol Gel
antivaricouse therapy
Brand name Sinedol gel ATC C05BA53 Form and Package gel 40 g (500 i.u.+150 mg+25 mg)/g DDD
Generic name heparin, dimethyl sulfoxide, dexpanthenol Pregnancy C Breastfeeding No excretion into breast milk, safe usage during breastfeeding.
INDICATIONS Sinedol gel is a combination of active substances intended for the treatment of sports injuries and other injuries of muscles, tendons, synovias and ligaments of the joints caused by bluntforce: contusions, hematomas, distortion,tennis elbow, tendons and synovial inflammation, bursitis. Also indicated in the treatment of peripheral venopathy, acute neuralgia, and humero-scapular periarthritis.
D D01 D01A D01AA D01AA01
DERMATOLOGICALS ANTIFUNGALS FOR DERMATOLOGICAL USE ANTIFUNGALS FOR TOPICAL USE Antibiotics nystatin
Nystatin
Antimycotic INDICATIONS Brand name Nystatin ATC D01AA01 Form and Package Ointment 5 g 100.000 i.u./g Ointment 20 g 100.000 i.u./g DDD Generic name nystatin Pregnancy C Breastfeeding Not excreted into milk. Nystatin ointment for the treatment of cutaneous and mucocutaneous infections caused by Candida (Monilia) albicans and other Candida strains.
D01AC D01AC08
IMIDAZOLE AND TRIAZOLE DERIVATIVES ketoconazole
Mycoseb
antifungal
Brand name Mycoseb ATC D01AC08 Form and Package shampoo 2% 1 x 100 ml DDD O 0,2 g
Generic name ketoconazole Pregnancy C Breastfeeding Possible excretion into breast milk. Avoid.
INDICATIONS Prevention and treatment of infections that are believed to be caused by the yeast Malassezia (formerly Pityrosporum), such as dandruff, seborrheic dermatitis and tinea (pityriasis) versicolor.
D03 D03A D03AX D03AX03
PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS CICATRIZANTS OTHAR CICATRIZANTS dexpanthenol
Panthenol
Vitamin
Brand name Panthenol ATC D03AX03 Form and Package ointment 30 g 5 % DDD
Generic name dexpanthenol Pregnancy No data available Breastfeeding No data available
INDICATIONS Burns of first and second degree, Irritation of skin caused by UV rays, Rash of gluteal parts of infants, Fissures of breast nipples at women in breastfeeding period, Chronic skin ulcers, Decubitus ulcers, Skin transplants in reciprocation with cortisone therapy, Treatment of dry, callously and aged skin.
D08 D08A D08AG D08AG02
ANTISEPTICS AND DISINFECTANTS ANTISEPTICS AND DISINFECTANTS IODINE PRODUCTS povidone-iodine
Povidon jod
antiseptic, disinfectant
Brand name Povidon jod ATC D08AG02 Form and Package ointment 1% 1 x 40 g foam 5 l foam 500 ml solution 100 ml solution 500 ml DDD
Generic name povidone-iodine Pregnancy Possible absorption of iodine and effect on thyroid gland of fetus Breastfeeding
Avoid
INDICATIONS Povidone-iodine ointment Povidone-iodine ointment is abroad spectrum antiseptic for topical treatment or prevention of infection in minor cuts and abrasions, simple surgical procedures and small burns. Povidone-iodine ointmentis intended also for the treatment of fungal and bacterial skin infections, pyoderma, treatment of decubitus infections and ulcus cruris. Povidone-iodine solution Povidone iodine solution intended for disinfecting the skin and mucous membranes before and after complex and simple surgery. Povidone-iodine foam Povidone iodine skin foam intended for hand disinfection of surgical staff and patient preoperative skin preparation
G G01 G01A
GENITO URINARY SYSTEM AND SEX HORMONES GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS OTHER ANTIINFECTIVES AND ANTISEPTICS povidone-iodine
G01AX G01AX11
Povidon jod
anti-infective, antiseptic INDICATIONS Brand name Povidon jod ATC G01AX11 Form and Package vaginal tablets 14 x 20 mg DDD Generic name povidone-iodine Pregnancy Possible absorption of iodine and effect on thyroid gland of fetus Breastfeeding Avoid Treatment of vaginitis caused by Candida, Trichomonas, for the treatment of non-specific and mixed infection and preoperative preparation of the vagina.
M M01AE M01AE01
MUSCULO-SKELETAL SYSTEM Propionic acid derivatives ibuprofen
Ibuprofen
NSAID
Brand name Ibuprofen ATC M01AE01 Form and Package 20 eff.tablets x 200 mg DDD O 1,2 g
Generic name ibuprofen DL-lysinate Pregnancy C Breastfeeding Compatible with breast feeding as minimal amounts excreted into milk.
INDICATIONS The drug is intended to eliminate mild to moderate pain such as headache, back pain, rheumatic or muscle pain, dysmenorrhea, toothache, lower fever and to relieve the symptoms colds and flu.
M M02 M02A M02AA M02AA15
MUSCULO-SKELETAL SYSTEM TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN ANTIINFLAMMATORY PREPARATIONS, NON-STEROIDS FOR TOPICAL USE diclofenac
Diclofenac
NSAID
Brand name Diclofenac ATC M02AA15 Form and Package gel 40 g 1% DDD O,P,R 0,1 g
Generic name diclofenac Pregnancy C (D in 3 trimester and in time of baby delivery)

rd
INDICATIONS Local symptomatic relief of pain and inflammation in: injuries of tendons, ligaments, muscles and joints (expansions, dislocations and contusions) localized forms of soft tissue rheumatism To relieve pain in mild arthritic conditions.
Breastfeeding Caution
N N02 N02B N02BA N02BA01
NERVOUS SYSTEM ANALGESICS OTHER ANALGESICS AND ANTIPYRETICS SALICYLIC ACID AND DERIVATIVES acetylsalicylic acid
Midol
analgesic, antipyretic INDICATIONS The pain of mild and moderate intensity: headache, toothache, neuralgia, arthralgia, muscle pain and similar painful conditions. Fever in adults: influenza, the common cold or similar infectious conditions that are accompanied by fever. Secondary prevention of myocardial infarction. Unstable angina pectoris.
Brand name Midol ATC N02BA01 Form and Package tablets 500 x 300 mg DDD O3g
Generic name acetylsalicylic acid Pregnancy C (1,2) D (3) Breastfeeding Avoid usage during breastfeeding. Possible appearance of Rey syndrome. Frequent usage of high doses can damage thrombocyte function and cause hypoprothrombinemia at breastfed infant.
N02BE01
paracetamol
Febricet
analgesic, antipyretic
Brand name Febricet ATC N02BE01 Form and Package syrup 100 ml (120 mg/5 ml) suppositories 5 x 200 mg DDD O3g
Generic name paracetamol Pregnancy No harmful effects to fetus have been reported. Breastfeeding Safe to use. Rash has been reported in breastfed infants.
INDICATIONS FEBRICET a mild analgesic and antipyretic. It is recommended that its short-term use in the following states headaches musculoskeletal disorders menstrual pain toothache symptomatic treatment of colds and flu mild to moderate pain associated with osteoarthritis Syrup For the symptomatic treatment of mild upper respiratory tract infections caused by viruses fever after immunization weak to moderately severe pain (headache, toothache, menstrual pain) Suppositories Symptomatic treatment of mild to moderately severe pain and /or fever
N02BE01
paracetamol
Grippostad hot drink

Brand name Grippostad hot drink ATC N02BE01 Form and Package Sachet 5x5 g/600 mg DDD O3g
Generic name paracetamol Pregnancy No harmful effects to fetus have been reported. Breastfeeding Safe to use. Rash has been reported in breastfed infants.
INDICATIONS Symptomatic treatment of mild to moderate pain (such as headache, toothache, menstrual pain and / or fever). It is used in children older than 10 years, adolescents and adults.
N02BE N02BE51
ANILIDES Paracetamol, combinations excl. psycholeptics
Caffebol
Brand name Caffebol ATC N02BE51 Form and Package tablets 500 x (460+50+10 mg) DDD
Generic name paracetamol, caffeine, codeine Pregnancy C, D in long term use Breastfeeding Not enough data available. Potentially toxic for child.
INDICATIONS Quickly relieve symptoms of pain. Caffebol is indicated for short term treatment of acute moderate pain that does not respond to paracetamol, ibuprofen or aspirin monotherapy: headache, migraine, menstrual pain, toothache, neuralgia and rheumatic pain (including myalgia, and back pain).
N02BE51
Paracetamol, combinations excl. psycholeptics
Febricet C
Brand name Febricet C ATC N02BE51 Form and Package eff. tablets 10 x (330+200 mg) DDD O3g
Generic name paracetamol, ascorbic acid Pregnancy No harmful effects to fetus have been reported. Breastfeeding Safe to use. Rash has been reported in breastfed infants.
INDICATIONS Symptomatic treatment of colds and influenza (high temperature, chills, and fever), and relieve mild to moderately severe pain such as headaches. Ascorbic acid is a supplement of vitamin C, in deficient conditions such as the flu or a cold.
R R01 R01A R01AA
RESPIRATORY SYSTEM NASAL PREPARATIONS Decongestants and other nasal preparations for topical use Sympathomimetics, plain
Nafazol 0,5, 1
Nasal decongestant
Brand name Nafazol ATC R01AA08 Form and Package Nasal drops, solution 10 ml DDD N 0,4 mg
Generic name naphazoline Pregnancy C Breastfeeding Unknown excretion into breast milk. No problems have been documented in humans.
INDICATIONS Symptomatic treatment of congestion of the nasal mucosa
R01B R01BA R01BA52
NASAL DECONGESTANTS FOR SYSTEMIC USE SYMPATHOMIMETICS pseudoephedrine, combinations
Rinasek
Sympathomimetic
Brend name Rinasek ATC R01BA52 Form and Package syrup 100 ml (5 ml/1,25+30 mg) tablets 10 x (2,5+60 mg) DDD O, 0,24 g
Generic name triprolidine, pseudoefedrine Pregnancy C, B Lactation safe in breast feeding
INDICATIONS Allergic rhinitis seasonal and nonseasonal Vasomotor (perennial) rhinitis Rhinitis, cold
R02 R02A R02AA R02AA15
THROAT PREPARATIONS THROAT PREPARATIONS ANTISEPTICS povidone-iodine
Povidon jod
antiseptic
INDICATIONS Brand name Povidon jod ATC R02AA15 Form and Package solution 0.85% 1 x 50 ml DDD Generic name povidone-iodine Pregnancy Possible absorption of iodine and effect on thyroid gland of fetus Breastfeeding Avoid Acute infections of the mouth and throat mucosa, for example. gingivitis and mouth ulcers. Oral hygiene, before, during and after dental procedures and interventions in the oral cavity.
R05 R05C R05CB R05CB06
COUGH AND COLD PREPARATIONS EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS MUCOLYTICS ambroxol
Ambroksol
mucolytic
Brand name Ambroksol ATC R05CB06 Form and Package syrup 100 ml 15 mg/5 ml eff. tablets 20 x 30 mg eff. tablets 10 x 60 mg DDD O 0,12 g
Generic name ambroxol Pregnancy No data available Breastfeeding No data available
INDICATIONS Mucolytic therapy in acute and chronic bronchopulmonary diseases associated with increased production and disorder formation and transport of mucus.
R05CB03
carbocisteine
Mucodyne
Mucolytic
Brand name Mucodyne ATC R05CB03 Form and Package capsules 30 x 375 mg syrup 100 ml (125 mg/5 ml) 2,5% syrup 100 ml (250 mg/5 ml) 5% DDD O 1,5 g
Generic name Carbocisteine Pregnancy No data available. Avoid. Breastfeeding No data available.
INDICATIONS Carbocisteine is mucolytic, and he is indicated for the adjuvant treatment of disorders of the respiratory tract caused by thick viscous secretions, including obstruction of the airways.
R06AB54
paracetamol, ascorbic acid, caffeine, chlorphenamine
Grippostad C
Brand name Grippostad C
Generic name paracetamol, ascorbic acid, caffeine, chlorphenamine DDD Pregnancy X Breastfeeding Contraindicated
ATC R06AB54 Form and Package
INDICATIONS Treatment of the symptoms of colds and flu infections, such as headache, muscle aches, nasal congestion and dry cough. GRIPPOSTAD C leads to the reduction of fever. Because of the fixed combination of active substances in drug GRIPPOSTAD C, the dose can be individually configured with respect to the predominant symptom. In such cases you should take your medicine of a different composition.
10 caps.x (200 mg + 150 mg +25 mg + 2,5 mg)
S S01 S01KA02
SENSE ORGANS DRUGS FOR THE TREATMENT OF EYE AND EAR hypromellose
Hemodrops
Viscoelastic substances
Brand name Hemodrops ATC S01KA02 Form and Package Eye drops 0,5% 10 ml DDD
Generic name hypromellose Pregnancy No data Breastfeeding No data
INDICATIONS Hemodrops, eye drops are used locally, for the symptomatic treatment of eye dryness (the syndrome of dry eye - keratoconjunctivitis sicca and xerophtalmia, eye irritation associated with insufficient tears production, the reduced secretion of tears in the elderly, as well as neuroparalytic tears hyposecretion). Also, it is used to prevent damage to the cornea when wearing hard contact lenses, while used as adjuvant therapy for disorders precorneal tear film (staphylococcal blepharitis and keratoconjunctivitis, herpetic keratitis, chemical and thermal eye injury).

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A A02 A02B A02BA A02BA02

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PROTON PUMP INHIBITORS omeprazole

proton pump inhibitor

Form and package gastroresistant capsules 14 x 20 mg gastroresistant capsules 15 x 20 mg

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proton pump inhibitor

Brand name Sabax ATC A02BC03 DDD O 30 mg

Form and package capsules 28 x 15 mg capsules 14 x 30 mg

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Brand name Laktuloza ATC A06AD11 DDD O 6,7 g

INN lactulose Pregnancy B Lactation Can be used.

INDICATIONS Chronic constipation. Hepatic encephalopathy (portal encephalopathy); hepatic coma.

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INN metformin hydrochloride Pregnancy B Lactation Avoid

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A10BB SULPHONYLUREA ANTIDIABETICS A10BB09 gliclazide

INN gliclazide Pregnancy C Lactation Avoid

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INN repaglinide Pregnancy C Lactation No data, avoid

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Inhibitor of thrombocytes aggregation

Brand name Clopidix ATC B01AC04 DDD O 75 mg

INN clopidogrel Pregnancy B Lactation Avoid

Form and package film-coated tablets 28 x75mg

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Inhibitor of thrombocytes aggregation

Brand name Ticlodix ATC B01AC05 DDD O 0,5 g

INN ticlopidine Pregnancy B Lactation Avoid

Form and package film tablets 30 x 250 mg

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B03 B03X B03XA B03XA01

Avoid, no data available

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B05 B05A B05AA07

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INN amino acids Pregnancy C Lactation Avoid

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B05BA10 aminoacids, minerals

INN amino acids Pregnancy C Lactation Avoid

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INN amino acids Pregnancy C Lactation Avoid

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B05BC SOLUTIONS PRODUCING OSMOTIC DIURESIS B05BC01 mannitol

INN mannitol Pregnancy No data available Lactation Avoid

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For Flushing of the bladder

INN mannitol, sorbitol Pregnancy C Lactation Caution

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C C01 C01B C01BC C01BC03

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antianginic with prolonged action

INN pentaerithrityltetranitrate (pentanitrole) Pregnancy C Lactation Avoid

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C01DA14 isosorbide mononitrate

INN Isosorbide mononitrate Pregnancy C Lactation Avoid

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C02 C02A C02AB C02AB02

ANTIHYPERTENSIVES CENTRALY ACTING ANTIADRENERGICS METHYLDOPA methyldopa