Tema: I.

INFLAMAIA ACUT i CRONIC MICROPREPARATE

62. Pericardit fibrinoas. Coloraie H-E. Indicaii: 1. Depozite de fibrin pe suprafaa epicardului. 2. Infiltraia epicardului cu leucocite. 3. Vase hiperemiate. 4. Miocardul. 28. Leptomeningit purulent. Coloraie H-E. Indicaii: 1. Infiltraie cu leucocite a leptomeningelui. 2. Puroi (leucocite) n spaiul subarahnoidan. 3. esutul cerebral edemaiat. 12. Miocardit interstiial. Coloraie H-E. Indicaii: 1. Infiltrat celular inflamator n stroma miocardului. 2. Fibrele musculare cu modificri distrofice. Tuberculoza miliar renal. Coloraie H-E. Indicaii: 1. Granulom tuberculos: a) focarul de necroz cazeoas n centrul granulomului; b) stratul de celule epitelioide; c) celule gigante polinucleate Langhans; d) stratul de celule limfoide. 2. esutul renal adiacent. II. PREPARATE MACROSCOPICE

82.

11. Pericardit fibrinoas (cord vilos) 32. Bronhopneumonie abcedant 33. Pneumonie franc lobar (stadiul de hepatizaie cenuie) 34. Pleurit fibrinoas 152.Peritonit fibrinoas 12. Cardioscleroz difuz 21. Echinococoza inimii III. ELECTRONOGRAM

7. Emigrarea leucocitelor neutrofile din lumenul capilarului

I.

62. . -. : 1. . 2. . 3. . 4. . 28. . -. : 1. . 2. () . 3. . 12. . -. : 1. . 2. . 82. ( -) : 1. : ) ; ) ; ) ; ) . 2. . II.

11. . 32. . 33. ( ). 34. . 152. . 12. . 21. . III. 7. .

ACUTE AND CHRONIC INFLAMMATION

Microspecimen 62. Fibrinous pericarditis. The fibrinous exudate is seen to consist of pink strands of fibrin jutting from the pericardial surface , there are many scattered inflammatory cells. 28.Pyogenic leptomeningitis. The exudate consists of dying and degenerate neutrophils, infecting organisms and liquefied tissues. There are many scattered inflammatory cells in severe cases and predominantly surrounding the leptomeningeal blood vessels in less severe cases. 82. Renal milliary tuberculosis Presence of small tubercle in the renal cortex. The granulomas exhibit classical central caseation surrounded by the macrophages, epithelioid cells and specific Langhans cells. 12. Interstitial myocarditis. It consists of inflammatory infiltrate in the myocardial stroma that leads to dystrophic changes in cardyomyocites. Macrospecimen 11. Fibrinous pericarditis. 12. Difuse cardiosclerosis. 21. Echinococus into heart 32. Focal pneumonia with abscess formation. 33. Lobar pneumonia (grey hepatisation). 34. Fibrinous pleuritis 152. Fibrinous peritonitis.

Electromicrography 7.Leukocytes peripheral position along the endothelial surface. This process of leukocyte accumulation is called margination. Subsequently, individual and than rows of leukocytes tumble slowly along the endothelium and adhere transiently (a process called rolling),, finally coming to rest of some point where they firmly (resembling pebbles or marbles over which a stream runs without disturbing them). In time the endothelium can be virtually lined by white cells, an appearance called pavementing. After firm adhesion, leukocytes insert pseudopods into the junctions between the endothelial cells, squeeze through interendothelial junctions, and assume a position between the endothelial cells and the basement membrane. Eventually, they traverse the basement membrane and escape the extravascular space.