Sartanii sau blocanii de receptori de angiotensin reprezint o clas relativ nou i modern de antihipertensive.

Principalul avantaj al sartanilor este c efectele adverse cum ar fi tusea sau angioedemul sunt munt mai rare dect la inhibitorii enzimei de conversie. Reprezentani ai clasei: Candesartan, Eprosartan, Irbesartan, Losartan, Olmesartan, Telmisartan, Valsartan. Aceste medicamente blocheaz receptorii de tip 1 (AT1) ai angiotensin ei II, ceea ce duce la vasodilataie i la scderea TA. Se prescriu n special la hipertensivii cu nefropatie diabetic (diabet zaharat tip II) cu microalbuminurie, HVS (hipertrofie ventricular stng), proteinurie sau n caz de apariie a tusei n cursul tratamentului cu IEC. n tabelul de mai jos sunt prezentate denumirile comerciale ale SARTANILOR att din Romnia ct i din Frana:

SARTANI (Blocanii de receptori de angiotensin)

Substana activ Denumirea comercial n Denumirea comercial n Frana ATACAND 4 mg, 8 mg, 16 mg CANDESARTAN 4 mg, 8 mg, 16 mg, 32 mg KENZEN 4 mg, 8 mg, 16 mg Sau n combinaii COKENZEN 8 mg/12,5 mg, 16 mg/12,5 mg (candsartan + hydrochlorot) HYTACAND 8 mg/12,5 mg, 16 mg/12,5 mg (candsartan + hydrochlorot) TEVETEN 300 mg Sau n combinaii COTEVETEN 600 mg/12,5 mg Romnia Candesartan ATACAND 8 mg, 16 mg

Eprosartan

Nu exist

Irbesartan

APROVEL 150mg, 300mg

(prosartan + hydrochlorot) APROVEL 75mg, 150mg, 300mg IRBESARTAN 75 mg, 150 mg, 300 mg Sau n combinaii COAPROVEL 150 mg/12,5 mg, 300 mg/12,5 mg, 300 mg/25 mg (irbsartan + hydrochlorot) COZAAR 50 mg,100 mg COZAAR 2,5 mg/ml pdre/solv susp buv

Losartan

COZAAR 50 mg Sau n combinaii

HYZAAR 50 mg/12,5 mg (LOSARTAN+HYDROCHLOROT) LOSARTAN 50 mg,100 mg Sau n combinaii FORTZAAR 100 mg/12,5 mg, 100 mg/25 mg (losartan + hydrochlorot) HYZAAR 50 mg/12,5 mg (losartan + hydrochlorot) LOSARTAN/HYDROCHLOROT 50 mg/12,5 mg, 100 mg/12,5 mg (losartan + hydrochlorot) ALTEIS 10 mg,20 mg, 40 mg OLMETEC 10 mg,20 mg, 40 mg Sau n combinaii AXELER 20 mg/5 mg, 40 mg/10 mg, 40 mg/5 mg (olmsartan+amlodipine) SEVIKAR 20 mg/5 mg 40 mg/10

Olmesartan

Nu exist

mg, 40 mg/5 mg (olmsartan+amlodipine) ALTEISDUO 20 mg/12,5 mg,20 mg/25 mg,40 mg/12,5 mg,40 mg/25 mg (olmsartan+hydrochlorot) COOLMETEC 20 mg/12,5 mg,20 mg/25 mg,40 mg/12,5 mg,40 mg/25 mg (olmsartan+hydrochlorot) MICARDIS 20mg, 40mg, 80mg PRITOR 20mg, 40mg, 80mg Sau n combinaii MICARDISPLUS 40 mg/12,5 mg,80 mg/12,5 mg,80 mg/25 mg

Telmisartan

MICARDIS 40mg, 80mg PRITOR 40mg, 80mg Sau n combinaii MICARDISPLUS 80/12.5mg

(TELMISARTAN+HYDROCHLOR (telmisartan + hydrochlorot) OT) PRITORPLUS 40/12,5 mg, 80/12,5 mg PRITOR PLUS 80mg/12,5mg (TELMISARTAN+HYDROCHLOR (telmisartan + hydrochlorot) OT) DIOVAN 80 mg, 160 mg NISIS 80 mg, 160 mg Sau n combinaii CO-DIOVAN 80 mg/12,5 mg TAREG 80 mg, 160 mg VALSARTAN 80 mg, 160 mg

Valsartan

(VALSARTAN+HYDROCHLOROT Sau n combinaii ) COTAREG 160 mg/12,5 mg,160 EXFORGE 5mg/80mg, 5mg/160mg, mg/25 mg, 80 mg/12,5 mg 10mg/160mg (VALSARTAN+HYDROCHLOR ( VALSARTAN+AMLODIPINA) OT) NISISCO 160 mg/12,5 mg,160

mg/25 mg, 80 mg/12,5 mg (VALSARTAN+HYDROCHLOR OT) VALSARTAN/HYDROCHLOR OT 160 mg/12,5 mg,160 mg/25 mg, 80 mg/12,5 mg (VALSARTAN+HYDROCHLOR OT) EXFORGE 5mg/80mg, 5mg/160mg, 10mg/160mg ( VALSARTAN+AMLODIPINA), EXFORGE HCT 10 mg/160 mg/12,5 mg, 10 mg/160 mg/25 mg, 5 mg/160 mg/12,5 mg, 5 mg/160 mg/25 mg