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Non-potable drinking water

Pathogenic microorganism (Entamoeba histolytica) enters the system

Microorgansim releases endotoxins

Hyperstimulation/ irritation of intestinal lining

Disruption of cell membrane

Increased water and electrolyte secretion Release of chemical mediators

Active secretion of Chloride and bicarbonate ions Activation of nociceptors

Inhibition of Sodium and Water reabsorption Nerve impulse sent to CNS

Increased Protein-rich fluid secretion CNS response: Vasodialtion,

Increased cell permeability

Abdominal cramping/pain

Overwhelms large bowel’s ability to reabsorb fluids

Increased fluid volume and decreased intestinal motility Abdominal distention

Watery stools (Diarrhea), Hyperactive bowel sounds Stimulation of vomiting center in the brain

Nausea, Anorexia

Continuous active fluid losses, Decreased food and fluid intake

Inadequate hydration and nutrition

Dry lips and mucous membranes, Sunken eyeballs, Poor skin turgor

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