Tema: I.

INFLAMAIA ACUT i CRONIC MICROPREPARATE

62. Pericardit fibri !a". Coloraie H-E. I dica#ii: 1. Depozite de fibrin pe suprafaa epicardului. 2. Infiltraia epicardului cu leucocite. 3. Vase hiperemiate. 4. Miocardul. 2$. Le%t!&e i 'it %(r()e t. Coloraie H-E. Indicaii: 1. Infiltraie cu leucocite a leptomenin elui. 2. !uroi "leucocite# $n spaiul subarahnoidan. 3. %esutul cerebral edemaiat. *2. Mi!cardit i ter"ti#ia). Coloraie H-E. I dica#ii: 1. Infiltrat celular inflamator $n stroma miocardului. 2. &ibrele musculare cu modificri distrofice. T(berc()!+a &i)iar re a). Coloraie H-E. I dica#ii: 1. 'ranulom tuberculos: a# focarul de necroz cazeoas $n centrul ranulomului( b# stratul de celule epitelioide( c# celule i ante polinucleate )an hans( d# stratul de celule limfoide. 2. %esutul renal adiacent. II. PREPARATE MACROSCOPICE

$2.

**. Pericardit fibri !a" ,c!rd -i)!". /2. 0r! 1!% e(&! ie abceda t //. P e(&! ie fra c )!bar ,"tadi() de 1e%ati+a#ie ce (ie. /2. P)e(rit fibri !a" *32.Perit! it fibri !a" *2. Cardi!"c)er!+ dif(+ 2*. 4c1i !c!c!+a i i&ii III. ELECTRONOGRAM

5. 4&i'rarea )e(c!cite)!r e(tr!fi)e di )(&e () ca%i)ar()(i

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

**. DEFGEHIJHKL MNGEOPGQER. /2. BF\]NQEG[^_PT FGIH`IMHNaWIHET. //. ?G[MIJHPT MHNaWIHET ,\RPQET \NGIXI IMNSNHNHET.. /2. DEFGEHIJHKL MVNaGER. *32. DEFGEHIJHKL MNGERIHER. *2. bEcc[JHKL OPGQEI\OVNGIJ. 2*. d`EHIOIOOIJ \NGQ]P. III. !"##$ 5. dWEXGP]ET HNLRGIcEVeHK` VNLOI]ERIa EJ MGI\aNRP OPMEVVTGP.

ACUT4 ANf CgRONIC INFLAMMATION

Micr!"%eci&e %&. '()*(+,-. /e*(0a*1(2(.. Rhe fibrinous eSudate is seen to consist of pinT strands of fibrin Uuttin from the pericardial surface V there are manW scattered inflammatorW cells. &3.P4,5e+(0 6e/2,me+(+5(2(.. Rhe eSudate consists of dWin and de enerate neutrophilsV infectin or anisms and liXuefied tissues. Rhere are manW scattered inflammatorW cells in seYere cases and predominantlW surroundin the leptomenin eal blood Yessels in less seYere cases. 3&. Re+a6 m(66(a*4 2-)e*0-6,.(. !resence of small tubercle in the renal corteS. Rhe ranulomas eShibit classical central caseation surrounded bW the macropha esV epithelioid cells and specific )an hans cells. 7&. I+2e*.2(2(a6 m4,0a*1(2(.. It consists of inflammatorW infiltrate in the mWocardial stroma that leads to dWstrophic chan es in cardWomWocites. Macr!"%eci&e 77. '()*(+,-. /e*(0a*1(2(.. 7&. 8(9-.e 0a*1(,.06e*,.(.. &7. E0:(+,0,0-. (+2, :ea*2 ;&. ',0a6 /+e-m,+(a <(2: a).0e.. 9,*ma2(,+. ;;. L,)a* /+e-m,+(a =5*e4 :e/a2(.a2(,+>. ;?. '()*(+,-. /6e-*(2(. 7@&. '()*(+,-. /e*(2,+(2(..

4)ectr!&icr!'ra%1h 7.Le-A,042eB. /e*(/:e*a6 /,.(2(,+ a6,+5 2:e e+1,2:e6(a6 .-*9a0e. Rhis process of leuTocWte accumulation is called mar ination. ZubseXuentlWV indiYidual and than ro[s of leuTocWtes tumble slo[lW alon the endothelium and adhere transientlW "a process called rollin #VV finallW comin to rest of some point [here theW firmlW "resemblin \pebbles or marbles oYer [hich a stream runs [ithout disturbin them]#. In time the endothelium can be YirtuallW lined bW [hite cellsV an appearance called paYementin . ^fter firm adhesionV leuTocWtes insert pseudopods into the Uunctions bet[een the endothelial cellsV sXueeze throu h interendothelial UunctionsV and assume a position bet[een the endothelial cells and the basement membrane. _YentuallWV theW traYerse the basement membrane and escape the eStraYascular space.