D.C.

I: Denominacin Comn
Internacional ( medicamento
)
Acetylsalicylic Acid
Acyclovir
Alendronate Sodium
Allopurinol
Alprozolam
Amiktriptyline
Hydrochloride
Amlodipine Besylate
Amoxicillin
Amphetamine (Mixed Salts)
Atenolol
Atorvastatin Calcium
Azithromycin
Benazepril Hydrochloride
Bisoprolol fumarate
Bupropion Hydrochloride
Buspirone Hydrchloride
Captopril
Carbamazepine
Cardidopa
Carisoprodol
Carvedilol
Cefprozil
Celecoxib
Cephalexin
Cetirizine Hydrochloride
Cimetidine
Ciprofloxacin Hydrochloride
Citalopram Hydrobromide
Clarithromuycin
Clindamycin Hydrochloride
Clonazepam
Clonidine Hydrochloride
Clopidogrel Bisulfate
Codeine Phosphate
Cyclobenzaprine

Max.
Potencia
( mg )

Solubilidad

Volumen
de
Solubilida
d

Clasificaci
n de
Solubilidad

Nmero
de
Dosis

Log P

Clasificacin
de
Permeabilida
d

BCS

500
400
70
100
0.5
25

3
10
33
0.1
0.01
100

166.67
40.00
2.12
1000.00
50.00
0.25

ALTA
ALTA
ALTA
BAJA
ALTA
ALTA

0.012
0.04
0.132
0.0004
0.00004
0.4

1.180
-1.590
-0.170
0.320
4.230
4.420

BAJA
BAJA
BAJA
BAJA
ALTA
ALTA

III
III
III
IV
I
I

5
500
30
100
20
500
40
10
100
30
25
200
25
350
25
500
400
500
10
800
500
40
500
300
2
0.3
75
60
10

1
4
100
26.5
0.1
0.01
33
33
312
1000
100
0.01
1
0.48
0.01
1.78
27
1
100
1
10
10
0.01
100
0.01
80
100
100
100

5.00
125.00
0.30
3.77
200.00
50000.00
1.21
0.30
0.32
0.03
0.25
20000.00
25.00
729.17
2500.00
280.90
14.81
500.00
0.10
800.00
50.00
4.00
50000.00
3.00
200.00
0.00
0.75
0.60
0.10

ALTA
ALTA
ALTA
ALTA
ALTA
BAJA
ALTA
ALTA
ALTA
ALTA
ALTA
BAJA
ALTA
BAJA
BAJA
BAJA
ALTA
BAJA
ALTA
BAJA
ALTA
ALTA
BAJA
ALTA
BAJA
ALTA
ALTA
ALTA
ALTA

0.004
0.016
0.4
0.106
0.0004
0.00004
0.132
0.132
1.248
4
0.4
0.00004
0.004
0.00192
0.00004
0.00712
0.108
0.004
0.4
0.004
0.04
0.04
0.00004
0.4
0.00004
0.32
0.4
0.4
0.4

3.650
-0.580
3.430
0.500
5.050
2.640
3.030
1.940
2.710
2.210
0.240
2.930
0.370
-2.890
3.120
-0.540
4.340
-0.670
3.110
0.790
1.320
3.860
2.720
0.790
2.180
2.780
3.740
1.450
4.310

ALTA
BAJA
ALTA
BAJA
ALTA
ALTA
ALTA
ALTA
ALTA
ALTA
BAJA
ALTA
BAJA
BAJA
ALTA
BAJA
ALTA
BAJA
ALTA
BAJA
BAJA
ALTA
ALTA
BAJA
ALTA
ALTA
ALTA
BAJA
ALTA

III
I
III
I
II
I
I
I
I
III
II
III
IV
II
IV
I
IV
I
IV
III
I
II
III
II
II
I
I
III
I

( mg/ml )