Dosis de Antibacterianos en Insuficiencia Renal

ANTIBACTERIANOS
Amikacina
Amoxicilina-Clav IV
Amoxicilina-Clav OR
Ampicilina
Azitromicina
Aztreonam
Cefazolina
Cefotaxima
Ceftazidima
Ceftriaxona
Cefuroxima
Ciprofloxacino IV
Ciprofloxacino OR
Claritromicina IV/OR
Clindamicina IV
Cloxacilina IV
Cotrimoxazol
Eritromicina IV
Ertapenem
Gentamicina
Imipenem
Levofloxacino IV
Levofloxacino OR
Linezolid OR/IV
Meropenem
Metronidazol IV
Penicilina G
Piperacilina-Tazob
Quinupristina-dalfop
Teicoplanina
Tobramicina
Vancomicina

Dosis habitual
adulto
1g /24h (7,5mg/Kg/12h)
1000mg /8h IV
875/125mg /8h oral
1g /6h
500mg /24h
1g /8h
1g /6h
1g /6h IV
2g /8h
1g /24h
750mg-1500mg/8h
400mg /12h
500-750mg /12h
500mg /12h
600mg /6h
1 g/6h
350 mg/8h

>50-90
60-90%/12h
1000mg/8h
875/125mg/8h
c/6h
sin cambios
100%
/8h
/8-12h
/8-12h
/8-12h
/8h
100%
100%
100%
sin cambios
sin cambios
1,00

1g /6h
1g /24h

100%
1g/24h

350mg /24h
(1,7mg/Kg/8h)
500mg /6h

60-90%/8-12h

500mg /24h
500mg /24h
600mg /12h
1000mg /8h
500mg 8h IV
2M /4h
4,5g /8h
500mg /8h
800 mg/ 24h
(6mg/kg/da)
350mg /24h
1g /12h

AJUSTE EN IR
50-10
30-70%/12-18h
0,5vial/12h
500/125mg/12h
/6-12h
sin cambios
75-50%
/12h
/12-24h
/24-48h
/12-24h
/8-12h
75-50%
75-50%
75%
sin cambios
sin cambios
0,50
100%
0,5g/24h
(ClCr<30)
30-70%/12h

<10
20-30%/24-48h
0,5vial/24h
500/125mg/24h
/12-24h
sin cambios
25%
/24-48h
/24h
/48h
/24h
/24h
50%
50%
50-75%
sin cambios
sin cambios
no
recomendado
50-75%
0,5g/24h
20-30%/24-48h

250-500mg/68h
500mg/24h
500mg/24h
sin cambios
1g/8h
100%
100%
4,5g/8h
sin cambios
/24h

250mg/6-12h
500mg/48h
500mg/48h
sin cambios
1g/12h
100%
75%
2,25g/6h
sin cambios
/48h

125250mg/12h
500mg/48h
500mg/48h
sin cambios
0,5g/24h
50%
25-50%
2,25g/8h
sin datos
/72h

60-90%/8-12h
1g/12h

30-70%/12h
1g/24-96h

20-30%/24-48h
1g/4-7 das

The Sandford Guide to Antimicrobial Therapy 2006.

ABX Guide v2.0 Johns Hopkins University. Division of Infectious Diseases para PDA.