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  • Ethyl Cellulose

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    Jameross B. Tabiano RPh
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    Ethyl cellulose is prepared from wood pulp or cotton by treating it with alkali and ethyl chloride over 10-20 hours at 90-150 degrees Celsius. It is a white to light tan cellulose ether used in pharmaceutical applications such as bioadhesive drug delivery systems, extended release solid dosage forms, emulsification, coating, flavor fixing, tablet binding and filling, viscosity increasing, compressibility enhancement, thickening and stabilization, and disintegration. It finds pharmaceutical uses due to its ability to control drug release rates.

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    Ethyl cellulose is prepared from wood pulp or cotton by treating it with alkali and ethyl chloride over 10-20 hours at 90-150 degrees Celsius. It is a white to light tan cellulose ether used in pharmaceutical applications such as bioadhesive drug delivery systems, extended release solid dosage forms, emulsification, coating, flavor fixing, tablet binding and filling, viscosity increasing, compressibility enhancement, thickening and stabilization, and disintegration. It finds pharmaceutical uses due to its ability to control drug release rates.

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    © All Rights Reserved
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    12 vizualizări4 pagini

    Ethyl Cellulose

    Încărcat de

    Jameross B. Tabiano RPh
    Ethyl cellulose is prepared from wood pulp or cotton by treating it with alkali and ethyl chloride over 10-20 hours at 90-150 degrees Celsius. It is a white to light tan cellulose ether used in pharmaceutical applications such as bioadhesive drug delivery systems, extended release solid dosage forms, emulsification, coating, flavor fixing, tablet binding and filling, viscosity increasing, compressibility enhancement, thickening and stabilization, and disintegration. It finds pharmaceutical uses due to its ability to control drug release rates.

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    © All Rights Reserved
    Descărcați ca PPTX, PDF, TXT sau citiți online pe Scribd
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    din 4

    ETHYL CELLULOSE

    Free flowing, white to light tan cellulose ether in which


    ethyl groups replace hydrogen in the hydroxyl groups of
    glucose residues
    SOURCES & PROCESS
    Ethyl cellulose is prepared from wood pulp
    or cotton by treatment of alkali and
    ethylation of the alkali cellulose with the
    ethyl chloride.
    Ethylation process takes place for over a
    period of ten to twenty hours at the
    temperature of 90-150 degrees celcius.
    PHARMACEUTICAL USES
    Applied in bioadhesive and mucoadhesive drug delivery systems
    Applied in Extended Release (ER) Solid dosage forms
    Emulsifier
    Coating agent
    Flavoring fixative
    Tablet Binder and Filler
    Viscosity-increasing agent
    Compressibility enhancer
    Thickening and Stabilizing agent
    Disintegrating Agent

    REFERENCES
    HTTP://WWW.DRUGS.COM/INACTIVE/ETHYLCELLULOSE-61.HTML

    HTTP://DWB4.UNL.EDU/CHEM/CHEM869E/CHEM869ELINKS/WWW.CHEM.VT.ED
    U/CHEM-DEPT/HELM/3434WOOD/NOTES4/CHEMICALS.HTML

    http://www.intechopen.com/books/cellulose-medical-pharmaceutical-
    and-electronic-applications/application-of-cellulose-and-cellulose-
    derivatives-in-pharmaceutical-industries#SEC6

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