Abercrombie 1

Heterochromia via Warrendburg Syndrome

William James Abercrombie
General Biology BSCC-1010
07!1"01#
Warrdenburg Syndrome is a genetic disorder that can cause some or all
o$ the $ollo%ing $eatures& dea$ness' (atches o$ %hite hair andor s)in' %ider
set eyes' and di*erent colored eyes +heterochromia iridium,- .his
heterochromia is %hat /0ll $ocus on in this (a(er-
.he chromosomes mostly a*ected by Warrdenburg0s that cause
(igment alterations are 1A2! and 3./4' %hich can also lead to %ide set eyes-
When the genes are coded incorrectly' melanin %hich is res(onsible $or
(igments o$ the eyes and s)in color' this can lead to abnormalities- /n
addition to (igment' a (ortion o$ the inner ear can be a*ected by mutations
o$ 1A2! and 3./4' and dea$ness can occur as a result-
Heterochromia iridium can be either t%o com(letely di*erent eye
colors +com(lete heterochromia,' a combination o$ colors in one or both eyes
+sectorial heterochromia,' or a bright light blue color %hich is usually an
obvious indicator o$ Warrdenburg0s-
.he occurrence rate o$ Warrdenburg0s is a((ro5- 1"0'000 and is
considered rare by the 67ce o$ 8are 9iseases +a lot o$ thought %ent into
that catchy name,- :n$ortunately no cure $or Warrdenburg0s has been $ound
as o$ yet' Warrdenburg0s sym(toms can be treated through corrective
surgery& hearing loss through cochlear im(lants' %ide set eyes through
cosmetic surgery' and neurosurgery i$ such damage is (resent- ;o% in the
case o$ heterochromia' %hy %ould anyone a cure $or that< .hat0s cra=y tal)-
Any%ay-
Heterochromia does not have to come $rom mutations o$ the genes' it
can be (assed through heredity as in Christo(her Wal)en' yeah' Christo(her
Wal)en>Boom?? 6r it can ha((en by in@ury' li)e 9avid Ai((in0 Bo%ie +a-)-a-
Biggy Stardust, %ho got into a Cght %ith his $riend over a lady and said
$riend had a Duic)er u((er hoo) and Bo%ie got (unched in the eye' also
leaving it (ermanently dilated' %hich loo)s a%esome by the %ay- Which is
Abercrombie "
the %hole reason / chose this to(ic' %hile / don0t li)e all o$ Bo%ie0s music
$rom the Spiders from Mars era' this song is (im(?? / gre% u( listening to this
album and it %as al%ays my $avorite song as it made no sense at all and
tal)ed about ray guns' roc)in0rolla bEEEEE0s' electric eyes' and s(ace $ace'
/ mean come on?? htt(&%%%-youtube-com%atch<vFGaD3%HI;Ja3