MSDS for Allqqua BioMedical, Inc. SilverSea® 240CT11 Rev.000 MATERIAL SAFETY DATA SHEET IN CASE OF EMERGENCY CONTACT - AquaMed Technologies, Inc. (216)-702-8550 SECTION 4 CHEMICAL NAME & SYNONYMS: SilverSeal® AMOUNT POLY (ETHYLENE OXIDE), PEO (Synonym) X-STATIC® CHOPPED FIBERS METHYL PARABEN PROPYL PARABEN DE-IONIZED WATER TRADE NAME SilverSeal® SECTION 2 HAZARD(S) Identification Sitver (X-STATIC® CHOPPED FIBER) CASRN 7440-22-4 Primary Entry Route: ingestion, inhalation, eye and skin contact 25% (of X-Static®) ACUTE EFFECTS: Ingestion: toxic, contains silver (defined by 40 CFR part 372) Inhalation: Irritant, avoid breathing dust Eyes: none noted ‘Skin: None noted SECTION 3 FIRST AID MEASURES Handle in accordance with good industrial hygiene and safety practices. These practices include avoiding unnecessary exposure and removal of the material from eyes, skin and clothing. SECTION 4 FIRE FIGHTING MEASURES Flash Ignition Temperature: 581°F (ASTM D1929-77) ‘Auto Ignition Temperature: 905°F Extinguishing Media: Water or Class "A” Extinguisher ‘Special Firefighting Precaution: Firefighters should wear full protective clothing inoluding, self contained breathing apparatus. Equipment should be decontaminated after use. Special Fire Hazards: Combustible thermoplastic may met, drip and produce heavy black smoke. SECTION § ACCIDENTAL RELEASE ‘Sweep up and place into containers for appropriate disposal Page 1 of 3ee MSDS for Alliqua BioMedical, Inc. SilverSeal® SECTION 6 HANDLING AND STORAGE Storage Requirements: Store in a cool dry place. HANDLING PRECAUTIONS Not an inhalation hazard during normal routine shipping and handling. Under aggressive physical manipulation, the potential exists for the generation of respirable silver/nyion fibers and dust. Regulatory Requirements: None SECTION 7 Personal Protection Equipment Measures Ventilation: Provide natural or mechanical ventilation to control exposure levels below airbome exposure limits. Respiratory Protection: Use NIOSH/MSHA approved respiratory protection equipment when airborne exposure limits are exceeded. Observe respirator use limitations specified by the manufacturer or NIOSH/MSHA. The respiratory protection program must comply with 29 CFR 1910.134, ‘Airborne Exposure Limits: X-Static Chopped Fiber ‘OSHA PEL: None established ACGIH TLV: None established Silver (component) OSHA PEL: 8hr TWA 0.01pm (fume/dust) STEL: = 2.0 ppm (fume/dust) ACGIH TLV: 8hr TWA ~0.20 ppm (fume/dust) Nylon (component) ‘OSHA PEL: 8hr TWA.- 15.0 ppm (fume/dust) STEL: NA ACGIH TLV: 8hr TWA 10 ppm (fume/oust) Protective Clothing: None required. Good industrial hygiene should be practiced tom avoid eye and skin contact, SECTION 8~ PHYSICAL DATA Boling Point F: Not Applicable Metting Point: Not Available Vapor Press, mmHg: Not Applicable Vapor Density Air: Not Applicable Solubility in H20: Not Applicable Specific Gravity H20 = 1: Not Applicable Bulk Density: Not Available Percent, Volatile by Volume %: Not Applicable Ph: 7-7.75 Appearance & Odor: Cleat, Translucent, Odorless, Sheet of Gel SECTION 9- STABILITY AND REACTIVITY Stability: Stable Incompatibility: Hydrogen peroxide decomposes violently on contact with the X-Statio®. = Acetylene forms explosive acetyiide. Ammonia forms fulminate — ike explosive compound. Hazardous Decomposition Products: Above 60°F; CO, CO,, HCN, NOX, AG,O and soot may occur. Page 2 of 3MSDS for Alliqua BioMedical, Inc. SliverSeal® SECTION 10- TOXICOLOGY INFORMATION ‘The potential effects of exposure to metal dust generated under aggressive use conditions are: Silver- excessive absorption and accumulation of silver in the body can cause argyria; a cosmetic change (bluish- grey discoloration of the skin, mucus membranes and eyes). Localized argyria may follow prolonged inhalation or swallowing of silver dust, Silver foil or silver discs under the skin of rats has produced local tumors. SECTION 11- ECOLOGICAL INFORMATION Ecotoxicity: not determined Environmental Fate: Environmental Transport: Not Determined Environmental Degradation: Not Determined Soil Adsorption/Mobilty: Not Determined SECTION 12- DISPOSAL CONSIDERATION SilverSeal® IS NOT A HAZARDOUS WASTE AS DEFINED BY 40 CFR 261. Dispose of waste materials by metal recovery, incineration, sanitary landill or other method in accordance to local, sate, or federal laws. Silver is a CERCLA listed substance. Consult your attorney or regulatory official for information on disposal. SECTION 13- TRANSPORTATION INFORMATION DOT Shipping Name: None, Not DOC Controlled DOT Hazard Class: N/A, Not DOT Controlled ID Number: None Special Provisions: None Packing Group: None Label: None SECTION 14~ REGULATORY INFORMATION USEPA FORA Hazardous Waste: None, Non-Hazardous RCRA Hazard Classttication: None CERCLA Hazardous Substance: Listed; under criteria of SOCFR 13456 CERCLA Reportable Quantity: Not Listed SARA EHS: Not Listed ‘SARA 319/312: This product contains the following substances that are defined as toxic chemicals under, and subject to reporting requirements of Tite Ill of 40 CFR part 372: Silver CASRN 7440-22-4, ‘OSHA: Sitver is considered a hazardous substance under 29 CFR1910.1200 TSCA: Not Listed; this product contains substances that that are considered toxio under 15 CFR part 12.2602: Silver CASRN 7440-22-4, Page 3 of 3