UMUC Biology 102/103 Lab 5: Meiosis

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Pre-Lab Questions
1. What major events occur during interphase?
The cell functions at its job, and prepares for mitosis by collecting
resources and duplicating organelles (G1) and genetic content (S), then
creating proteins needed for nuclear division (G2).
2. A person, residing in a location where they are exposed to the sun
often, develops a mutation in some of their skin cells resulting in
cancer. Consider whether their offspring will be born with the same
mutation. Use scientific evidence to support your answer.
It would be highly unlikely that the persons offspring will be born with
same skin cancer mutation because the mutation occurred in the
persons skin cells. Skin cells are somatic cells (body cells) and are not
involved in meiosis or reproduction. For the mutation to be passed on
to the offspring, a sex cell (sperm or egg) would have to carry the
mutation.
The other questions that will be answered:
Experiment 1: Following Chromosomal DNA Movement through
Meiosis
Data Tables and Post-Lab Assessment
Trial 1 - Meiotic Division Beads Diagram:
Prophase I
Metaphase I
Anaphase I
Telophase I

Prophase II
Metaphase II
Anaphase II
Telophase I
Cytokinesis
Trial 2 - Meiotic Division Beads Diagram:
Prophase I
Metaphase I
Anaphase I
Telophase I
Prophase II
Metaphase II
Anaphase II
Telophase I
Cytokinesis
Post-Lab Questions
What is the ploidy of the DNA at the end of meiosis I? What about at
the end of meiosis II
How are meiosis I and meiosis II different?
Why do you use non-sister chromatids to demonstrate crossing over?
What combinations of alleles could result from a crossover between BD
and bd chromosomes?
How many chromosomes were present when meiosis I started?
How many nuclei are present at the end of meiosis II? How many
chromosomes are in each?
Identify two ways that meiosis contributes to genetic recombination.

Why is it necessary to reduce the number of chromosomes in gametes,

but not in other cells?
Blue whales have 44 chromosomes in every cell. Determine how many
chromosomes you would expect to find in the following:
Sperm Cell:
Egg Cell:
iii.

Daughter Cell from Mitosis:

Daughter Cell from Meiosis II:

Research and find a disease that is caused by chromosomal mutations.
When does the mutation occur? What chromosomes are affected?
What are the consequences?
Diagram what would happen if sexual reproduction took place for four
generations using diploid (2n) cells.
Experiment 2: The Importance of Cell Cycle Control
Data Tables and Post-Lab Assessment
Post-Lab Questions
Record your hypothesis from Step 1 in the Procedure section here.
What do your results indicate about cell cycle control?
Suppose a person developed a mutation in a somatic cell which
diminishes the performance of the bodys natural cell cycle control
proteins. This mutation resulted in cancer, but was effectively treated
with a cocktail of cancer-fighting techniques. Is it possible for this
persons future children to inherit this cancer-causing mutation? Be
specific when you explain why or why not.
Why do cells which lack cell cycle control exhibit karyotypes which look
physically different than cells with normal cell cycle.
What are HeLa cells? Why are HeLa cells appropriate for this
experiment?