Three ways to pick out the prominent house in your chart:

1st Technique
The 2nd house in the Navamsa chart when superimposed on the Rasi,
would indicate the house where you would be prominent. What is the logic
behind this?
Navamsa is the chart of luck and the 5th house in Navamsa indicate the
required luck in the future like when you are in the adult or past the
middle age. 10th to the 5th house is the sign style where you would have
the required luck. This turns out to be the 2nd house to Navamsa.
Superimpose this house onto the Rasi which indicates the area of activity
where you should focus. That house in the Rasi is where you would be
prominent.
2nd Technique:
Step 1
------Memorise the table below.
Type Of Signs Signs P Pushkara Navamsas
Fire Signs Aries, Leo, Sagi Li & Sg
Earthy Signs Taurus, Virgo, Capricorn Ta & Pi
Airy Signs Gemini, Libra, Aquarius Ta & Pi
Watery Signs Cancer, Scorpio, Pisces Cn & Vi
Find out your Ascendant sign and note the correspondent Pushkara
Navamsa.
Step 2
------Use these two signs found in Step (1) above and find out which houses it
overlay in the Rasi chart.
Step 3
------The 2 lords of the houses above and the two said houses will dominate
one's life.
Given the right dasas and if they form Yogas, one would become
prominent in society in those areas of life ruled by these two houses.
Mud would be slung at you and then you would emerge as a Lotus.

3rd Technique
---------------Your Atmakaraka in Navamsa called the Karakamsa when superimposed
by sign onto the Rasi chart, that house is where you need to fulfill yourself
in life. Hence you would put in your maximum effort into that sphere of
activity ruled by that house.