DR.

IRINA ROMAN

FARMACOLOGIE

TRATAMENTUL ANTIHIPERTENSIV
I. DIURETICELE
1. - DE ANSA: - FUROSEMID administrat n urgenele hipertensive - iv
- BUMETAMID
- PIRETANID
- AC. ETACRINIC
2. TIAZIDICE SI COMPUI SULFONAMIDICI:
- HIDROCLOROTIAZIDA
- CLOPAMIDA
- INDAPAMIDA folosit cel mai frecvent n HTA
3. CE ECONOM. K+:

- SPIRONOLACTONA (+FUROSEMID = DIUREX)

- AMILORID
- TRIAMTEREN
- Eplerenona (2005/2006)

4. - OSMOTICE: - MANITOL
- GLICEROL

II.INHIBITORI AI ENZIMEI DE CONVERSIE A ANGIOTENSINEI

PERINDOPRIL
(Prestarium)
FOSINOPRIL
(Monopril)
RAMIPRIL
(Tritace)
LISINOPRIL
(Ranolip)

TRANDOLAPRIL
(Gopten)
BENAZEPRIL
QUINAPRIL
CILAZAPRIL
ENALAPRIL
(Renitec)
CAPTOPRIL

III. BLOCANII RECEPTORILOR DE ANGIOTENSIN

SARTANII (BRA)

LOSARTAN (Cozaar)
VALSARTAN (Diovan)
CANDESARTAN (Atacand)
IRBESARTAN (Aprovel)
TELMISARTAN (Micardis)
EPROSARTAN
OLMESARTAN

IV. BLOCANTELE CANALELOR DE CALCIU

A. DIHIDROPIRIDINELE
Gen.I: - NIFEDIPINA
- NICARDIPINA
- FELODIPINA (Auronal)
Gen.II. - NIMODIPINA
- NISOLDIPINA
- NITRENDIPINA
Gen.III: - AMLODIPINA (Norvasc)
- LACIDIPINA (Lacipil)
- LERCANIDIPIN (Leridip)
B. FENILALCHILAMINELE
- VERAPAMIL
- GALOPAMIL
- FALIPAMIL
C. BENZOTIAZEPINELE
- DILTIAZEM

V.INHIBITORI SIMPATICI
A. INHIBITORI ADRENERGICI PERIFERICI
- GUANETIDINA
- GUANADREL
B. INHIBITORI ADRENERGICI CENTRALI
- ALFAMETILDOPA
- CLONIDINA

- GUANABENZ
- MOXONIDINA
C. INHIBITORI ADRENERGICI CENTRALI SI PERIFERICI
- REZERPINA
D. ALFA BLOCANTE
neselective: FENOXIBENZAMINA, FENTOLAMINA
selective: PRAZOSIN, DOXAZOSIN, TERAZOSIN

E. BETA BLOCANTE
NESELECTIVE

1+ 2

PROPRANOLOL
OXPRENOLOL
PINDOLOL
NADOLOL
SOTALOL
TIMOLOL
BETAXOLOL
CARVEDILOL (Dilatrend)

SELECTIVE
1
ATENOLOL (Tenormin)
METOPROLOL (Betaloc)
BISOPROLOL (Concor)
NEBIVOLOL (Nebilet)
ACEBUTOLOL (Sectral)
ESMOLOL
CELIPROLOL
ALTE

a.VASODILATATOARE ORALE
N HTA MODERATA / SEVERA

HIDRALAZINA
MINOXIDIL

b. VASODILATATOARE INJECTABILE
N URGENE HTA

DIAZOXID - i.v. efect 5-20

Reacii adeverse - GLICEMIA=> NU n uz
NITROPRUSIAT DE Na - i.v. efect 1 2
- asistenta medical va monitoriza TA i pulsul

MEDICAIA ANTIARITMICA
1.
2.
3.
4.
5.
6.
7.
8.
9.

PROPAFENONA (RYTHMONORM)
FLECAINIDA
FENITOINA
MEXILETIN
AMIODARONA
IBUTILIDA
BRETILIUM
VERAPAMIL
DILTIAZEM

MEDICAIA INSUFICIENEI CARDIACE

CARDIOTONICE
DIGOXIN
DIGITOXIN
LANATOSID
ACERTIL DIGITOXINA
STROFANTINA

MEDICAIA BOLII ISCHEMICE A INIMII

NITRII NITRAI
NITROGLICERINA
ISOSORBIDDINITRAT
ISOSORBIDMONONITRAT
PENTA-ERITRILI-TETRANITRAT (Nitropector)