Anti- mites Anti fungus Anti dandruf Eliminates Odor Shiny coat Wash your dog with neem defense shampoo, and you'll discourage biting insects, ticks and fleas, ringworm, mange mites, any skin disorders or fungal infections . Does your dog have skin problems? Itches or bald spots? Or is it being harassed by mites or fleas? Try Neem Defense Pet Shampoo. DIRECTION FOR USE leave the shampoo in for at least 5 minutes before rinsing. Do this two or three times a week.