Please complete the following two assignments by Friday October 2nd.

Assignment #1
An
oncogene
is a gene that. when mutated or; expressed at abnormally-high levels. contributes
to converting a normal cell into a cancer cell.
Please select an oncogene and answer the
following questions:
1. What is the gene and on what chromosome and where on the chromosome is it
located? Note: The short arm of the chromosome is "p" (for petite) and the long arm is
"q". The last number is the location on the arm.
2. What is the normal function of this gene?
3. What specific pathological condition results from expression of the mutant form of the
gene? (Cancer types)
4. If known, how was the gene originally identified?
5. Current treatment for most prevalent cancer type associated with mutant gene?

Assignment #2
A
tumor suppressor
gene, is a gene that protects a cell from one step on the path to cancer.
When this gene mutates to cause a loss or reduction in its function, the cell can progress to
cancer, usually in combination with other genetic changes.
Please select a tumor suppressor
and answer the following questions:
1. What is the gene and on what chromosome and where on the chromosome is it
located? Note: The short arm of the chromosome is "p" (for petite) and the long arm is
"q". The last number is the location on the arm.
2. What is the normal function of this gene?
3. What specific pathological condition results from expression of the mutant form of the
gene? (Cancer types)
4. If known, how was the gene originally identified?
5. Current treatment for most prevalent cancer type associated with mutant gene?