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MarcosBanda

NervousSystemLabReport

Thislabreportisaboutactionpotentials.Theelectricactivityinanormalcellmembrane
environment,environmentsmodifiedbyvarioustoxins,andactionpotentialsobservedinhuman
reflexes.Inresponsetoastimulus,theexcitablecellmembraneofaneuroncellgoesfroma
restingstatetodepolarization,followedbyrepolarizationtotherestingstateagainthisprocess
iscalledactionpotential.Depolarizationoccurswithinaneuronwheresodiumionsentersthe
cellandraisethechargefromanegativetoapositivelevel.Repolarizationoccurswhenthe
membraneofaneuronbecomesmorepermeable,whichallowspotassiumionstodiffuseoutof
theneuroncausingthemembranetoreturntotherestingstate.Afterrepolarizationtheperiod
whenaxonscannotbestimulatedtogenerateanewactionpotentialiscalledtherefractory
periodwhichlimitsimpulsestoanaverageof100persecond.Sometoxinscancauseneuronal
membranesactionpotentialtonolongerfunctionproperlywhichcancausedeath.

Description:Depolarizationiswherethevoltage,goesuporwherethesodiumionsenterand
changethelevelfromnegativetopositive.Repolarizationiswherethepotassiumionsdiffuse
outofthecellmembraneorwhereitgoesbacktotherestingstate.Andtherefractoryperiodis
wherethecellmembranecannotcreatenewactionpotential.

ColumnA

ColumnB

SyntheticToxin

Willdestroythemyelincoveringyouroptic
nervesandmotorneurons.

Batrachotoxin

Comesfromapoisondartfrog.Itwillcause
voltagegatedsodiumchannelstoopenata
morenegativemembraneandalsoprevents
theirinactivation.

DendrotoxinK

Willblockthevoltagegatedpotassium
channelsinamatteroftime.

Sevoflurane

Willopenmorepotassiumchannelsin
neuronsofthereticularformationinthe
brainstem.

Maculotoxin

ComesfromtheBlackWidowSpiderwill
blockthesodiumchannels.

Latrotoxin

ComesfromthesnakeKrait,enhances
acetylcholinerelease.

Bungarotoxin

ComefromtheBlueRingedOctopus,will
blockacetylcholinenicotinicreceptor.

Tetrodotoxin

ComesfromtheScorpion,willblocksodium
channels.

Apamin

ComesfromaConeSnail,willblockyour
potassiumchannel.

Charybdotoxin

ComesfromPufferfish,willblockpotassium
receptors.

Conotoxin

Comesfrombees,onetypeoftoxinblocks
voltagesensitivecalciumchannelsanother
willblockvoltagesensitivesodiumchannels,
andoneblocksAChreceptors.

Description:ThenameofthetoxinsareincolumnAandtheeffectithaswillbeinColumnB.
ManytoxinswillwillblockPotassium,SodiumorCalciumchannelsoropenthemup.Resulting
inaoverflowornotenoughpotassium,calciumorsodium.Whichwillaffectactionpotentialby
again,eitheroverflowingornothavingenoughtohavedepolarizationorrepolarizationperiod.


CranialNerves

Nerve

Function

OlfactoryNerve

Smell

OpticNerve

Vision

OculomotorNerve

EyeMovement,EyeDialation

TrochlearNerve

EyeMovement

TrigeminalNerve

SensoryInformation(Touch,Pain)Chewing
Muscles

AbducensNerve

EyeMovement

FacialNerve

Taste

VestibulocochelearNerve

Taste

GlossopharyngealNerve

Taste

VagusNerve

Sensory,MotorandAutonomicFunctionsof
Viscera(glands,digestion,heartrate)

SpinalAccessoryNerve

Controlsmusclesusedinheadmovement

HypogloassalNerve

Controlsmusclesofthetongue

Description:ManyofthenervesareconnectedtoActionPotentialduetosignalsyourbrain
sendstothesenerves.Justlikeactionpotential.Thesenervessendsignalsinamatterofa
second.


Reflexs

BicepReflexTest(Biceps
BrachiiMuscle,
MusculocutaneousNerve)

++

UpwardMovementofthe
forearm

TricepsReflexTest(Triceps
BrachiiMuscle,Radial
Nerve)

DownwardMovementofthe
forearm

BrachioradialisReflexTest
(SupinatorMuscles,
BrachioradialasTendon)

++

SupinationoftheForearm
andHand

HoffmannsTest

TestsforpyramidalTract
Lesions

PatellarReflex(Quadriceps
Muscle,PatellarTendon)

++

Clonus,Jerkingoftheknee

AchillesReflexTest(Soleus
Muscle,CalcanealTendon)

++

PlantarFlexionofthefoot

BabinskiReflex

PlantarFlexion,bigtoe

CheckCrossReflexs

++

Whilepickingupaheavy
objectwithonearm,the
otherarmwillmovelaterally
tobalanceyourself

Descritption:Manyofthesereflexesarejustlikeactionpotentialandhaveacloselinktoaction
potential.Veryquickly,yourreflexeswillflexinmanyways.Eitheritbeaflexionorpronation.

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