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NervousSystemLabReport
Thislabreportisaboutactionpotentials.Theelectricactivityinanormalcellmembrane
environment,environmentsmodifiedbyvarioustoxins,andactionpotentialsobservedinhuman
reflexes.Inresponsetoastimulus,theexcitablecellmembraneofaneuroncellgoesfroma
restingstatetodepolarization,followedbyrepolarizationtotherestingstateagainthisprocess
iscalledactionpotential.Depolarizationoccurswithinaneuronwheresodiumionsentersthe
cellandraisethechargefromanegativetoapositivelevel.Repolarizationoccurswhenthe
membraneofaneuronbecomesmorepermeable,whichallowspotassiumionstodiffuseoutof
theneuroncausingthemembranetoreturntotherestingstate.Afterrepolarizationtheperiod
whenaxonscannotbestimulatedtogenerateanewactionpotentialiscalledtherefractory
periodwhichlimitsimpulsestoanaverageof100persecond.Sometoxinscancauseneuronal
membranesactionpotentialtonolongerfunctionproperlywhichcancausedeath.
Description:Depolarizationiswherethevoltage,goesuporwherethesodiumionsenterand
changethelevelfromnegativetopositive.Repolarizationiswherethepotassiumionsdiffuse
outofthecellmembraneorwhereitgoesbacktotherestingstate.Andtherefractoryperiodis
wherethecellmembranecannotcreatenewactionpotential.
ColumnA
ColumnB
SyntheticToxin
Willdestroythemyelincoveringyouroptic
nervesandmotorneurons.
Batrachotoxin
Comesfromapoisondartfrog.Itwillcause
voltagegatedsodiumchannelstoopenata
morenegativemembraneandalsoprevents
theirinactivation.
DendrotoxinK
Willblockthevoltagegatedpotassium
channelsinamatteroftime.
Sevoflurane
Willopenmorepotassiumchannelsin
neuronsofthereticularformationinthe
brainstem.
Maculotoxin
ComesfromtheBlackWidowSpiderwill
blockthesodiumchannels.
Latrotoxin
ComesfromthesnakeKrait,enhances
acetylcholinerelease.
Bungarotoxin
ComefromtheBlueRingedOctopus,will
blockacetylcholinenicotinicreceptor.
Tetrodotoxin
ComesfromtheScorpion,willblocksodium
channels.
Apamin
ComesfromaConeSnail,willblockyour
potassiumchannel.
Charybdotoxin
ComesfromPufferfish,willblockpotassium
receptors.
Conotoxin
Comesfrombees,onetypeoftoxinblocks
voltagesensitivecalciumchannelsanother
willblockvoltagesensitivesodiumchannels,
andoneblocksAChreceptors.
Description:ThenameofthetoxinsareincolumnAandtheeffectithaswillbeinColumnB.
ManytoxinswillwillblockPotassium,SodiumorCalciumchannelsoropenthemup.Resulting
inaoverflowornotenoughpotassium,calciumorsodium.Whichwillaffectactionpotentialby
again,eitheroverflowingornothavingenoughtohavedepolarizationorrepolarizationperiod.
CranialNerves
Nerve
Function
OlfactoryNerve
Smell
OpticNerve
Vision
OculomotorNerve
EyeMovement,EyeDialation
TrochlearNerve
EyeMovement
TrigeminalNerve
SensoryInformation(Touch,Pain)Chewing
Muscles
AbducensNerve
EyeMovement
FacialNerve
Taste
VestibulocochelearNerve
Taste
GlossopharyngealNerve
Taste
VagusNerve
Sensory,MotorandAutonomicFunctionsof
Viscera(glands,digestion,heartrate)
SpinalAccessoryNerve
Controlsmusclesusedinheadmovement
HypogloassalNerve
Controlsmusclesofthetongue
Description:ManyofthenervesareconnectedtoActionPotentialduetosignalsyourbrain
sendstothesenerves.Justlikeactionpotential.Thesenervessendsignalsinamatterofa
second.
Reflexs
BicepReflexTest(Biceps
BrachiiMuscle,
MusculocutaneousNerve)
++
UpwardMovementofthe
forearm
TricepsReflexTest(Triceps
BrachiiMuscle,Radial
Nerve)
DownwardMovementofthe
forearm
BrachioradialisReflexTest
(SupinatorMuscles,
BrachioradialasTendon)
++
SupinationoftheForearm
andHand
HoffmannsTest
TestsforpyramidalTract
Lesions
PatellarReflex(Quadriceps
Muscle,PatellarTendon)
++
Clonus,Jerkingoftheknee
AchillesReflexTest(Soleus
Muscle,CalcanealTendon)
++
PlantarFlexionofthefoot
BabinskiReflex
PlantarFlexion,bigtoe
CheckCrossReflexs
++
Whilepickingupaheavy
objectwithonearm,the
otherarmwillmovelaterally
tobalanceyourself
Descritption:Manyofthesereflexesarejustlikeactionpotentialandhaveacloselinktoaction
potential.Veryquickly,yourreflexeswillflexinmanyways.Eitheritbeaflexionorpronation.