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Hemophilia
Causes
Hemophiliaiscausedbyageneticmutation.Themutationsinvolvegenesthatcodefor
proteinsthatareessentialinthebloodclottingprocess.Thebleedingsymptomsarise
becausebloodclottingisimpaired.
Death Rate
Theirmedianagewas22years,73%werewhite,79%hadhemophiliaA,42%had
severedisease,and67%hadvisitedan
HTC.During7575personyears(PYs)of
observation,236personsdiedanage
adjustedmortalityrateof40.4
deaths/1000PYs65%ofdeathswere
HIVrelated.
Pictures
Unexplainedandexcessivebleedingfromcutsorinjuries,oraftersurgeryordentalwork
Manylargeordeepbruises
Unusualbleedingaftervaccinations
Pain,swellingortightnessinyourjoints
Bloodinyoururineorstool
Nosebleedswithoutaknowncause
Ininfants,unexplainedirritability
Treatment
Slowinjectionofthehormonedesmopressin
Vaccinations
Physicaltherapy
Treatment Centers
Children'sHospitalOakland
Children'sHospitalofOrangeCounty
CityofHopeNationalMedicalCenter
3
OrthopaedicHospitalofLosAngeles
RadyChildren'sHospitalSanDiego