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  • Kolkata - Anatomy Revision Programme PDF

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    Antar Inenigog
    72 vizualizări8 pagini
    Identify the cell that secretes intrinsic factor in gastric glands. (AIIMS pattern 2016). Gastric intrinsic factor is essential for absorption of vitamin B12 (and erythropoiesis) in pernicious anaemia, autoantobodies destroy the parietal cells.

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    Identify the cell that secretes intrinsic factor in gastric glands. (AIIMS pattern 2016). Gastric intrinsic factor is essential for absorption of vitamin B12 (and erythropoiesis) in pernicious anaemia, autoantobodies destroy the parietal cells.

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    © All Rights Reserved
    Descărcați ca PDF, TXT sau citiți online pe Scribd
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    72 vizualizări8 pagini

    Kolkata - Anatomy Revision Programme PDF

    Încărcat de

    Antar Inenigog
    Identify the cell that secretes intrinsic factor in gastric glands. (AIIMS pattern 2016). Gastric intrinsic factor is essential for absorption of vitamin B12 (and erythropoiesis) in pernicious anaemia, autoantobodies destroy the parietal cells.

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    © All Rights Reserved
    Descărcați ca PDF, TXT sau citiți online pe Scribd
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    din 8

    Q12.

    Identifythecellthatsecretes
    intrinsicfactoringastricglands.
    (AIIMSpattern2016)
    DRRAJESHKKAUSHALANATOMYREVISIONPROGRAMME FRIDAY,MAY20,2016

    Q12.Identifythecellthatsecretesintrinsicfactorin
    gastricglands.(AIIMSpattern2016)

    LMofpartofgastricmucosa,showingcellsingastricg

    a)A
    b)B
    c)C
    d)D

    Ans.a)A.
    Explanation:Parietalcellsecretehydrochloricacidandintrinsicfactorinthegastric
    glands.Itisidentifiedbythelargesize,relativelyclearcytoplasminthecell.
    A:Parietalcell,B:Mucusneckcell,C:Surfacemucuscell,D:Chiefcell

    Gastricmucosa

    270x

    Parietalcellcomparisonwithchiefcell(Magnifiedview):

    535x

    A.Parietal(Oxyntic)cell:
    1.Lightlyeosinophiliclargecuboidalcell,withcentralsphericalnucleus(friedegg
    appearance).
    2.Relativelyclearcytoplasm.
    3.Predominantlypresentintheupperhalfofthegland,moresointhebodyregion
    ofthegastricgland.
    GastricintrinsicfactorisessentialforabsorptionofvitaminB12(anderythropoiesis).In
    perniciousanaemia,autoantobodiesdestroytheparietalcellsleadingtodeficiencyof
    intrinsicfactorandresultantvit.B12absorption,whichfurtherleadsto
    megaloblasticanaemia.

    Gastricgland:Celltypes

    GastricglandCelltypes

    B.Mucuscell:
    1.Small,darkstained,columnarcell
    2.Locatedclosetogastricpit(neckregionofgastricgland)

    C.Chiefcell:
    1.Small,basophiliccolumnarcell
    2.Morenumerousinthelowerhalfoftheglandmoresoatthebase(fundus)ofthe
    gastricgland.
    3.Containzymogengranules/pepsinogen.

    D.Neuroendocrinecell:
    1.Smallcells,foundatthedeeperareasbase(fundus)ofthegastricgland,along
    withchiefcells.
    2.Thesecretoryactivitiesofthechiefandparietalcellsarecontrolledbytheautonomic
    nervoussystemandthehormonegastrin,secretedbytheenteroendocrinecellsof
    thepyloricregionofthestomach.
    TheenteroendocrinecellsarealsocalledAPUD(amineprecursoruptakeand
    decarboxylation)cells.

    E.Stemcell:
    1.Pluripotentcell,locatedattheisthmusregionofgastricgland.
    2.Helpsinrepairofgastricepithelium.

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