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NAME:_________________ Reg.NO:__________________Points_________________
Each of the following questions contains four suggested answers, choose
the best one.
1Antibody can bind to
A antigenic determinents C the whole antigen molecule
B BCR D TCR
2Factors influence immunogenicity include
A foreignness B molecular size C chemical composition D all above
3 Haptens are the molecules that
A possess antigenicity C possess immunogenicity
B are large protein D can induce the production of antibody
4 The first immunoglobulin class produced in a primary response to an antigen is
A IgA B IgG C IgM D IgE
5 The most abundant immunoglobulin class in serum is
A IgA B IgG C IgM D IgE
6 The Ig which serves an important effector function at mucous membrane surface is
A IgA B IgG C IgM D IgE
7 The domains by which immunoglobulin bind to epitope are
A constant region B variable region C framework region D hinge region
8 The monomer of IgM is composed of
A two γheavy chains,and two κor two λlight chains.
B two μheavy chains,and two κor two λlight chains.
A two εheavy chains,and two κor two λlight chains.
A two δheavy chains,and two κor two λlight chains.
9 Papain can digest the entire IgG into
A two Fab fragment and one Fc fragment.
A one Fab fragment and one Fc fragment.
A two F(ab’)2 fragment and one Fc fragment.
A one F(ab’) 2 fragment and pFc’.
10 C1q-binding site of IgM is located in
A CH1 B CH2 C CH3 D CH4
11The most efficient Ig involved in the classical pathway of complement activation is
A IgA B IgG C IgM D IgE
12 In the classical pathway of complement activation, C3 convertase is
A C4b2a B C3bBb C C4b2a3b D C3bBb3b
13 The fragment that does not belong to the anaphylatoxin is
A C3a B C3b C C4a C5a
14 The fragment involves in the opsonization is
A C3a B C3b C C4a C5a
15 The regions that encode Class I HLA molecules are
A locus A B locus B C locus C D all above
16 In Class I MHC molecules,peptide-binding site consist of
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A α1 and α2 domains B α1 and α3 domains C α1 and β1 domains D β2m
17 Biological role of the MHC proteins do not contribute to
A A fundamental role in regulating immune responses.
B Ag presentation
C Self-MHC restriction.
D Control of B cell development
18 The component which is capable of lysing microorganisms is
A C1-9 B C5-9 C C3-5 D C8-9
19 In the classical pathway of complement activtion,the activation sequence is
A C123456789 B C124536789 C C142356789 D C124356789
20Which property does not belong to cytokines
A Pleiotropy B Redundancy C Synergy D Specificity
21 The formation of C3bBb can be inhibited by
A DAF B factor I C factor H D all above
22 MBL activates the complement system via its ability to
A directly cleave C4 Cdirectly cleave C2
B directly cleave C3 D bind to C1q
3. Opsonins include
2
5. All of the following are secondary lymphoid organs except…
7. T cells do not…
A. express CD3
B. produce cytokines to help other cell types.
C. Mediate their functions by cell to cell contact.
D. Recognize protein antigens without APC cells’ associated.
A. express CD4.
B. Produce IL-4,IL-10 et al.
C. Involve in inflammatory .
D. Help B cell activation.
9. Tc cells do not…
A. express CD8.
B. Mediate killing of virus infected cells .
C. release lytic granules
D. recognize antigens with MHC class II molecles.
10. All of the following are true about cell mediated immunity Except…
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D.usually express α /β dimers.
15. The method that detects the antibody blocking the actions of a microorganism is:
A. Agglutination
B. Enzyme-linked immunosorbent assay
C. Neutralization
D. Single radial immunodiffusion
18. Hemolytic disease of the newborn due to RhD incompatibility depends upon
the…
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D. The first pregnancy of the RhD+mother with RhD- fetus.
19. All of the following are true about immune-complex mediated type III
hypersensitivity except
20. All of the following are true about delayed-type hypersensitivity except…
A. is mediated by T lymphocytes.
B. includes contact sensitivity.
C. includes the tuberculin reaction.
D. includes Farmer’s lung.
22. Which of the following cell types is not involve in antibody production…
A. Cytotoxic T cells. C. Th2 cells.
B. B cells. D. Macrophages.
23. On the B cell surface, receptors for antigen are associated with…
A. B5 molecules C. MHC class I molecules.
B. Igα and Igβ . D. MHC class II molecules.
24. All of the following are true about memory humoral immune response except…
A. Usually produce more antibodies of IgG class
B. The lag period is much shorter than the primary immune response.
C. The affinity of antibodies is maturated.
D. Produce IgM antibodies without class switching.
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A. membrane IgM and IgD stimultaneously.
B. CD2 molecules.
C. CD3 molecules.
D. IgG that can bind several different unrelated antigens.
29. Both immune complex disease and delayed type hypersensitivity involve…
A. IgG or IgM antibodies.
B. Complement.
C. Phagocytic cells.
D. B cells.
1. A B C D 2. A B C D 3. A B C D 4. A B C D 5. A B C D
6. A B C D 7. A B C D 8. A B C D 9.A B C D 10.A B C D
11. A B C D 12. A B C D 13. A B C D 14. A B C D 15. A B C D
16. A B C D 17.A B C D 18 A B C D 19. A B C D 20. A B C D
21. A B C D 22. A B C D 23.A B C D 24. A B C D 25. A B C D
26. A B C D 27. A B C D 28. A B C D 29 A B C D 30. A B C D
31. A B C D 32. A B C D 33. A B C D 34. A B C D 35. A B C D
36. A B C D 37.A B C D 38 A B C D 39. A B C D 40. A B C D
41. A B C D 42. A B C D 43.A B C D 44. A B C D 45. A B C D
46. A B C D 47. A B C D 48. A B C D 49 A B C D 50. A B C D
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NAME:_________________ Reg.NO:__________________