Generic Name Dosage Mechanism of Action Side Effects/ Adverse Nursing Considerations

Reaction

Ipratropium + 2.5 ml Ipratropium bromide is an • bronchospasm 1.Inhaler may be used 15

Salbutamol anticholinergic (parasympatholytic) • chest pain and fast, minutes before exercise to
agent which, based on animal studies, pounding, or uneven prevent exercise-induced
appears to inhibit vagally mediated heart beats bronchospasm.
reflexes by antagonizing the action of • swelling of your 2. Patient may use tablets and
Brand Name Timing acetylcholine, the transmitter agent ankles or feet inhaler at the same time.
released from the vagus nerve. • pain or burning with Monitor for toxicity.
Combivent Every 6 hours Anticholinergics prevent the increases urination 3.Warn the patient about the
in intracellular concentration of cyclic risk of paradoxical
• increased blood
guanosine monophosphate (cyclic bronchospasm and if it occurs,
pressure
GMP) which are caused by interaction stop drug immediately.
of acetylcholine with the muscarinic 4.Teach patient to use the
receptor on bronchial smooth muscle. inhaler correctly: Shake it, clear
the throat, expel as much air as
possible from the lungs, inhale
Classifications Indications References Contraindications
deeply while releasing the drug
• History of from the inhaler, hold breath for
Bronchodilators PPD’s Nursing Drug Guide 2nd edition hypersensitivity to soya several seconds.
Anti-ashmatic that relax lecithin or related food 5.Use of a spacer may improve
muscles in the products such as soybean delivery.
airways and and peanut. 6. Wait for 2 minutes between
increase air flow
puffs of inhaler.
to the lungs.
7.If the patient is also using a
steroid inhaler, use the
bronchodilator first, then wait 5
minutes before using the steroid.
8.Wash the canister with warm
water and soap at least once a
week.
 Generic Name Dosage Mechanism of Action Side Effects/ Adverse Nursing Considerations
Reaction
Salbutamol is a selective 2-
Salbutamol 2.5 ml + NSS 2ml adrenomimetic agent stimulating • Headache 1.Assess cardio-respiratory
Sulfate mainly the 2-adrenergic receptors • Tremor function, heart rate and rhythm
and to a lesser extent 1-adrenergic • Tachycardia and breathe sounds.
receptors in the myocardium. The • Hypertension 2. Give after shaking
stimulation of the 2 receptors leads metered dose inhaler; have
• Anxiety
Brand Name Timing to adenylate cyclase activation and patient exhale and place
• Rarely nausea,
cAMP accumulation, alterations in moutnpiece in mouth, inhale
vomiting
Ventar Every 4 hours the methyl transferase activity, slowly while depressing inhaler,
Nebulizing decrease in the calcium ion • skin rash can be hold breath, remove inhaler,
Solution Alternate with intracellular concentration. Due to observed. exhale slowly; allow at least 1
Combivent these changes bronchial smooth min between inhalations.
muscle relaxation and inhibition of 3.Store in light resistance
mast cell degranulation develop. The container do not expose to
antiasthmatic action of Salbutamol is temperature over 30ºC
related to the decrease of edema and 4.Avoid getting aerosol in eyes
mucus secretion. or blurring may result.
Classifications Indications References Contraindications 5.Instruct patient to limit
caffeine products.
bronchospasm in PPD’s Nursing Drug Guide 2nd Hypersensitivity to some 6.Tell patient to stop drug
Anti-asthmatic patients with edition of the drug ingredients. immediately if bronchospasm
reversible airway occurs.
obstruction: mild
and moderate
attacks of dyspnea
in patients
suffering from
bronchial asthma;
mild and moderate
bronchoobstruction
in patients with
chronic bronchitis
and lung
emphysema.
 Generic Name Dosage Mechanism of Action Side Effects/ Adverse Nursing Considerations
Reaction

Clarithromycin 2.5 ml Inhibits and interferes with bacterial • Gi disturbances 1. Monitor hepatic and
• Diarrhea, Nausea and hematologic status.
protein synthesis by binding to the 50s 2. Assess bowel pattern
vomiting
ribosomal subunits of bacterial discontinue if diarrhea
• Taste disturbances
chromosome. • Headache and rashes occurs.
Brand Name Timing 3. Instruct patient to take all
medications prescribed for
Klaricid 2 times a day the length of time ordered
and to continue drug
therapy.
4. Advised patient not to
chew or crush tablets.
Classifications Indications References Contraindications 5. Advice patient to contact
physician if vaginal
Anti-infectives Treatment of PPD’s Nursing Drug Guide 2nd edition Hypersensitivity to itching, loose-foul
respiratory tract macrolides. Liver and smelling stools and furry
infections such kidney damage. tongue is observed.
as pneumonia,
bronchits etc.
Generic Name Dosage Mechanism of Action Side Effects/ Adverse Nursing Considerations
Reaction

Budesonide 1 NEB t NSS Controls the rate of protein synthesis; • Headache, erythema,
2ml rash, vomiting, asthma,
depresses the migration of
diarrhea.
polymorphonuclear leukocytes, • Chest pain, edema,
fibroblasts; reverses capillary flushing, hypertension,
Brand Name Timing permeability and lysosomal palpitation, syncope,
stabilization at the cellular level to tachycardia.
Asmavent 2 times a day
prevent or control inflammation. Has
Pulmoneb • Dizziness,
potent glucocorticoid activity and weak
dysphonia, emotional
mineralocorticoid activity.
lability, fatigue, fever
Classifications Indications References Contraindications

Anti-asthmatics Bronchial PPD’s Nursing Drug Guide 2nd edition Not intended for rapid
asthma relief of acute episodes of
asthma where an inhaled
short-acting
bronchodilator is
required.

Generic Name Dosage Mechanism of Action Side Effects/ Adverse Nursing Considerations

Prednisone 6 ml Glucocorticoids are naturally occurring
hormones that prevent or suppress
inflammation and immune responses
when administered at pharmacological
Brand Name Timing doses. At a molecular level, unbound
glucocorticoids readily cross cell
Pred ID Daily
membranes and bind with high affinity
suspension Post breakfast
to specific cytoplasmic receptors. This
binding induces a response by
modifying transcription and, ultimately
protein synthesis to achieve the
steroid’s intended action. Such actions
may include: inhibition of leukocyte
infiltration at the site of inflammation,
interference in the function of
mediators of inflammatory response,
and suppression of humoral immune
responses.
Classifications Indications References
Hormone related Allergic and PPD’s Nursing Drug Guide 2nd edition
drugs inflammation
conditions
Reaction
1.Assess patient’s condition
• Fluid and electrolyte before therapy and regularly
disturbances thereafter to monitor drug
effectiveness.
• Visual disturbances
• Growth retardation 2.Obtain baseline weight, blood
pressure and electrolyte levels.
• Hyperglycemia
3.assess for potassium depletion.
• Skin atrophy
1.Assess patient and his family’s
knowledge on drug therapy.
• 4.. Assess for signs and symptom
of infection.
5.Assess for adrenal function for
hypothalamic-pituitary-adrenal
axis suppression.
6. Give with food or milk to
decrease Gi symptom
7. Instruct patient not to stop
medication without medical
advice because it can result to
adrenal crisis.
8. Do not attempt toverdose.
Contraindications
Gastric and duodenal
disorders, systemic
fungal, glaucoma and
hypersensitivity.