A Guide toTitration of OryContin@ Adequare retier in r-t-M-E

Titrate patients every 1 to 2 days,

T if necessary

lncrease the dose of OxyOontin@

Tablets by 25Y" to 507o, if necessary
10 mq Tablets
(refer to the chart when titrating
CSr upward from 1Omg q12h).
ffirU Do not increase the dosing frequency.
b58&.
t raaat-t
Manage exacerbations of pain with
M immediate-release medication.

Elevate the dose of OxyContin@

tt**tw q12h 0ose

0xy0onlin. E Tablets if more than 2 doses of
immediate-release opioid medication
per day are required.

Mundipharma Pharmaceuticals Sdn Bhd

74, Jalan University, 46200 Petaling Jaya, Selangor, Malaysia
Tel : (603) 7966 0730 Fax : (603) 7957 9909

Mundipharma Pharmaceuticals Pte Lld

.l

Tel
Q Hoe Chiang Road, #3 2O-04l05 Keppel Towers, Singapore
: (65) 6511 1165 Fax : (65) 6511 1167
08931 5
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 Multiply mg per day of current
TOTAL opioid by conversion factor below :

DAILY
DOSg
CURRENT
oProrD

fxnny6: OratWryQlrc 2onq = zugx ffi : Oxycodoru ronrg o

dl

n) llvtorylfiru 2ont0 : 2ontfl x [i s] = Oxycdorc 3orw

J
o
o
X
o
All proporyphene patients should be corverled to 10 mg OryContin@ q12h
C;onversion from transdermal bntarryl to OnrContin@ taUets : approximately 1 omg q 1 2h of Ci4pontin@
tadeb, should be initially substituted br eaci 2Spgrlhr bntanyl tnnsdermal patch.
Reftf€nce: nWEninitidirEOqEonlin@lcrpatierrspsdousVbkirgoffuijs,heconservativeconensi'lratiosfiornKM
Wy tN ErEl J lvld. 1 985; 31 3:84-951 arc reasonable starting pctnt altrough not verified in uiell-contolled fials.
@: OryContin is a Registered Tradomark.
t&/or^ l/wn pi,4., fuf4;'t"<. t^lf Ag-"