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Ophthalmology Mnemonics
Post Enucleation Socket Syndrome (PESS)
Ptosis Enophthalmos Deep upper Sulcus Slack lower lid
Secondary glaucoma: NIPPLES Neovascular Iridoschisis PXF Pigmentary Lens (phacolytic/phacomorphic) Iridocorneal Endothelial syndromes Seclusio pupillae (in iritis) +trauma (angle recession)
Leakage from retinal vessels Ulceration (aphthous/genital) Pustules after skin trauma (Pathergy test) Scratching leaves lines (dermatographism) Erythema nodosum Thrombophlebitis
Trauma Overstretched zonules (buphthalmos / megalocornea) AR with Pupil ectopy Isolated AR Cystathione beta-synthase deficiency (homocystinuria) Marfans Weill-Marchesani syndrome
Microbiology Mnemonics
Capsulated pathogenic organisms are Some Killers Have Pretty Nice Capsules Quote:
S Streptococcus pneumoniae K Klebsiella pneumoniae H Haemophilus influenzae P Pseudomonas aeruginosa N Neisseria meningitidis C Cryptococcus neoformans
Remeber... All bacilli are gram negative except "L.DATTA" Quote:
Endothelial cells/ Edema Negative (gram- bacteria) DIC/ Death Outer membrane TNF O-antigen X-tremely heat stable IL-1 Nitric oxide/ Neutrophil chemotaxis
Acute post-streptococcal glomerulonephritis: classic presentation Quote:
"Sore throat, Face bloat, Pi$$ coke": Sore throat: 1 week ago Face bloat: facial edema Pi$$ coke: coke-coloured urine Alternatively, short version: "Throat, bloat and coke".
Staphylococcus aureus: diseases caused SOFT PAINS: Quote:
Skin infections
Osteomyelitis Food poisoning Toxic shock syndrome Pneumonia Acute endocarditis Infective arthritis Necrotizing fasciitis Sepsis
Food poisoning: bugs inducing "Eating Contaminated Stuff Causes Very Big Smelly Vomit": Quote:
E. coli O157-H7 [undercooked meat, esp. hamburgers] Clostridium botulinum [canned foods] Salmonella [poultry, meat, eggs] Vibrio parahaemolyticus [seafood] Bacillus cereus [reheated rice] Staphylococcus aureus [meats, mayo, custard] Clostridium perfringens [reheated meat] Vibrio vulnificus [seafood]
Streptococcus pyogenes: virulence factors SMASHED: Quote:
Necrotising fasciitis and myositis Impetigo Pharyngitis Pneumonia Lymphangitis Erysipelas and cellulitis Scarlet fever/ Streptococcal TSS
Endocarditis: lab results suggesting it "High Tech Lab Results Point At Endocarditis": Quote:
Hematuria Thrombocytopenia
Leukocytosis, -penia Red blood cell casta Proteinuria Anemia Elevated ESR
Clostridium difficile: disease caused Quote:
"Difficult to be in a Closet with someone having explosive foul smelling diarrhea, because it would smell and there would be no air in there. Clostridium Difficile causes explosive foul smelling diarrhea and is an anaeorbe (no air).
Trichomaniasis: features Quote:
5 F's: Flagella Frothy discharge Fishy odor (sometimes) Fornication (STD) Flagyl (metronidazole) Rx
Nematodes: ones spreading by egg ingestion Quote:
"ATE eggs": Ascaris Lumbricoides Trichuris trichuira Enterobius vermicularis spread by ingestion of eggs (vs skin invasion or insect bite)
Food poisoning: bugs inducing Quote:
"Eating Contaminated Stuff Causes Very Bad Smelly Vomit": E. coli O157-H7 [undercooked meat, esp. hamburgers] Clostridium botulinum [canned foods] Salmonella [poultry, meat, eggs] Vibrio parahaemolyticus [seafood] Bacillus cereus [reheated rice] Staphylococcus aureus [meats, mayo, custard] Clostridium perfringens [reheated meat] Vibrio vulnificus [seafood]
Meningitis: risk factors Quote:
"Can Induce Severe Attacks Of Head PAINS": Cancer Immunocompromised state Sinusitis
Age extremes Otitis Head trauma Parameningeal infection Alcoholism Infections (systemic, esp. respiratory) Neurosurgical procedures Splenectomy
Influenza infection: clinical manifestations Quote:
"Having Flu Symptoms Can Make Moaning Children A Nightmare": Headache Fever Sore throat Chills Myalgias Malaise Cough Anorexia Nasal congestion
Toxoplasma gondii: manifestations Quote:
"My Cat Eats Mice": Mononucleosis-like illness Chorioretinits/ Congenital infection Encephalitis Myocarditis
Urease positive organisms Quote:
PUNCH: Proteus (leads to alkaline urine) Ureaplasma (renal calculi) Nocardia Cryptoccocus (the fungus) Helicobacter pylori
AIDS pathogens (T-cell suppression) worth knowing Quote:
"The Major Pathogens Concerning Complete T-Cell Collapse": Toxoplasma gondii M. avium intracellulare Pneumocystis carinii Candida albicans Cryptococcus neoformans Tuberculosis
South in Gujarati is DAXIN...simple...Southern blot is for DNA West in Gujarati is PASCHIM...so...Western Blot is for Protein and Northern is simply for M RNA(just to remember N with M) its how they eat north -roti - rna south -dosa - dna west -pizza - protein
BACILLUS Quote:
Bombs Make PAGes Bombs-for Bacillus............Bamboo stick appearance Make-Macdyean reaction P-PLET medium A-Agar medium[medusa head] Ge-Gelatin stab S-Solid medium....String in pearls reaction.......!!!!
Neisseria Meningitidis Quote:
Loafers Eat BMTC ticket Of Mahatma Gandhi in Chennai L-Lenticular colonies E-Exacting growth requirements B-blood agar[weak hemolysis] M-Muellar hinton agar T-Thayer martin agar C-Chocolate agar O-Oxidase positive MG-utilize Glucose and Maltose C-Catalase positive
PSEUDOMONAS pathogenecity Remember "PSEUDOMONAS" for memorise pathogenesity of pseudomonas infection Quote:
P= pulmonary infection S= septicemia E= eye infection; endocarditis U= UTI D= (dermatological)Ecthyma gangrenosum O= otitis media M= meningitis
P- Pregnancy,Prostatitis A-acute febrile illness,atypical mycobacteriae T-TB,Trauma,Transplant rejection,Treated UTI C-Corticosteroid use ,cyclophosphamide H-H.influenza infection
Encephalitis: differential HE'S LATIN AMERICAN: Herpesviridae Enteroviridae (esp. Polio) Slow viruses (esp. JC, prions) Syphilis Legionella/ Lyme disease/ Lymphocytic meningoencephalitis Aspergillus Toxoplasmosis Intracranial pressure Neisseria meningitidis Arboviridae Measles/ Mumps/ Mycobacterium tuberculosis/ Mucor E. coli Rabies/ Rubella Idiopathic Cryptococcus/ Candida Abscess Neoplasm/ Neurocysticercosis Neurocysticercosis should be assumed with recent Latin American immigrant patient unless proven otherwise. Eggs that float in Saturated Saline Remember, "I HATE fertilised eggs" Hymenolepis nana and Hookworm Ascaris lumbricoides Trichuris trichura Enterobius vermicularis So the fertilised eggs of all the above float in saturated saline. Everything else sinks. Posted by ImedRx Comments (0) Labels: Microbiology, Mnemonics
Pharmacology Mnemonics
HMG-CoA reductase inhibitors (statins): side effects, contraindications, interactions HMG-CoA: Side effects: Hepatotoxicity Myositis [aka rhabdomyolysis] Contraindications: Girl during pregnancy/ Growing children Interactions: Coumarin/ Cyclosporine
Beta-blockers: main contraindications, cautions ABCDE: Asthma Block (heart block) COPD Diabetes mellitus Electrolyte (hyperkalemia)
Clopidogrel: use CLOPIdogrel is a drug that prevents CLots, an Oral Platelet Inhibitor (OPI).
Amiodarone: action, side effects 6 P's: Prolongs action potential duration Photosensitivity Pigmentation of skin Peripheral neuropathy Pulmonary alveolitis and fibrosis Peripheral conversion of T4 to T3 is inhibited -> hypothyroidism
Beta blockers: members "The NEPAL Prime Minister": Timolol Nadolol Esmolol Pindolol Atenolol Labetalol Propranolol Metoprolol
Ca++ channel blockers: uses CA++ MASH: Cerebral vasospasm/ CHF Angina Migranes Atrial flutter, fibrillation Supraventricular tachycardia Hypertension Alternatively: "CHASM": Cererbral vasospasm / CHF Hypertension Angina Suprventricular tachyarrhythmia Migranes
Beta-blockers: nonselective beta-blockers "Tim Pinches His Nasal Problem" (because he has a runny nose...): Timolol Pindolol Hismolol Naldolol Propranolol
Antiarrhythmics: classification I to IV MBA College In order of class I to IV: Membrane stabilizers (class I) Beta blockers Action potential widening agents Calcium channel blockers
EnoXaprin only acts on factor Xa. Monitor Xa concentration, rather than APTT anti hyprtensive safe for pregnancy are--My N.H.L --Quote:
M = mental retardation E = electrolyte imbalance T = tolerance H = headache/ hepatotoxicity, rebound HTN Y = psYchological upset D = dry mouth, drowsiness O = oedema, orthostatic hypotension P = Parkinsonism A = Anemia [+ve coomb's test]
sodium nitroprusside clinical uses: MR. CHIEF SURGERY IN EMERGENCY Quote:
Mr. = Acute MI chief = Acute CHF Surgery = maintain hemostasis during surgeries emergency = hypertensive emergencies
antihypertensives used in emergencies............. Saurav Ganguly HELP Quote:
Quote:
Anorexia Blurry vision Constipation/ Confusion Dry Mouth Sedation/ Stasis of urine
Antimuscarinics: members, action "Inhibits Parasympathetic And Sweat": Quote:
Ipratropium Pirenzepine Atropine Scopolamine _Muscarinic receptors at all parasympathetic endings sweat glands in sympathetic.
Aspirin: side effects ASPIRIN: Quote:
Asthma Salicyalism Peptic ulcer disease/ Phosphorylation-oxidation uncoupling/ PPH/ Platelet disaggregation/ Premature closure of PDA Intestinal blood loss Reye's syndrome Idiosyncracy Noise (tinnitus)
Benzodiazapines: ones not metabolized by the liver (safe to use in liver failure) LOT: Quote:
"Ben is off with the flu": Benzodiazepine effects off with Flumazenil.
Benzodiazepenes: drugs which decrease their metabolism "I'm Overly Calm": Quote:
Isoniazid Oral contraceptive pills Cimetidine _ These drugs increase calming effect of BZDs by retarding metabolism.
Benzodiazepines: actions "Ben SCAMs Pam into seduction not by brain but by muscle": Quote:
Action: "Botulism Bottles up the Ach so it can't be the released": Related bungarotoxin: "Botulism is related to Beta Bungarotoxin (beta-, not alphabungarotoxin--alpha has different mechanism).
Cholinergics (eg organophosphates): effects If you know these, you will be "LESS DUMB": or SLUDGE Quote:
Lacrimation Excitation of nicotinic synapses Salivation Sweating Diarrhea Urination Micturition Bronchoconstriction
Delerium-causing drugs ACUTE CHANGE IN MS:
Quote:
Antibiotics (biaxin, penicillin, ciprofloxacin) Cardiac drugs (digoxin, lidocaine) Urinary incontinence drugs (anticholinergics) Theophylline Ethanol Corticosteroids H blockers Antiparkinsonian drugs Narcotics (esp. mepridine) Geriatric psychiatric drugs ENT drugs Insomnia drugs NSAIDs (eg indomethacin, naproxin) Muscle relaxants Seizure medicines
Direct sympathomimetic catecholamines DINED: Quote:
Sevoflurane Halothane Isoflurane Nitrous oxide Enflurane _ If want the defunct Methoxyflurane too, make it MoonSHINE.
Ipratropium: action Atropine is buried in the middle: iprAtropium, so it behaves like Atropine. Lead poisoning: presentation ABCDEFG: Quote:
Melancholic [classic name for atypical depression] Anxiety Obesity disorders [anorexia, bulemia] Imagined illnesses [hypochondria] Social phobias _ Listed in decreasing order of importance. _ Note MAOI is inside MelAnchOlIc.
Methyldopa: side effects METHYLDOPA: Quote:
Mental retardation Electrolyte imbalance Tolerance Headache/ Hepatotoxicity psYcological upset Lactation in female Dry mouth Oedema Parkinsonism Anaemia (haemolytic)
Monoamine oxidase inhibitors: members "PIT of despair": Quote:
Miosis Orthostatic hypotension Respiratory depression Pain supression Histamine release/ Hormonal alterations Increased ICT Nausea Euphoria Sedation
Morphine: effects at mu receptor PEAR: Quote:
The Narcotic Antagonists are NAloxone and NAltrexone. _ Important clinically to treat narcotic overdose.
Parkinsonism: drugs SALAD: Quote:
Selegiline Anticholinenergics (trihexyphenidyl, benzhexol, ophenadrine) L-Dopa + peripheral decarboxylase inhibitor (carbidopa, benserazide) Amantadine Dopamine postsynaptic receptor agonists (bromocriptine, lisuride, pergolide)
Phenytoin: adverse effects PHENYTOIN: Quote:
P- interactions Hirsutism Enlarged gums Nystagmus Yellow-browning of skin Teratogenicity Osteomalacia Interference with B metabolism (hence anemia) Neuropathies: vertigo, ataxia, headache
Physostigmine vs. neostigmine LMNOP: Quote:
Lipid soluble Miotic Natural Orally absorbed well Physostigmine _ Neostigmine, on the contrary, is: Water soluble Used in myesthenia gravis Synthetic Poor oral absorption
Pupils in overdose: morphine vs. amphetamine "MorPHINE: Fine. AmPHETamine: Fat": Quote:
Morphine overdose: pupils constricted (fine). Amphetamine overdose: pupils dilated (fat).
Serotonin syndrome: components Causes HARM: Quote:
Vomiting Alopecia Liver toxicity Pancreatitis/ Pancytopenia Retention of fats (weight gain) Oedema (peripheral oedema) Appetite increase Tremor Enzyme inducer (liver)
Succinylcholine: action, use Quote:
Succinylcholine gets Stuck to Ach receptor, then Sucks ions in through open pore. You Suck stuff in through a mouth-tube, and drug is used for intubation.
Tricyclic antidepressants: members worth knowing "I have to hide, the CIA is after me": Quote:
Clomipramine
Imipramine Amitrptyline _ If want the next worth knowing, the DNDis also after me: Desipramine Norrtriptyline Doxepin
Tricyclic antidipressents (TCA): side effects TCA'S: Quote:
ThrombocytopeniaCardiac (arrhymia, MI, stroke) Anticholinergic (tachycardia, urinary retention, etc) Seizures
Vigabatrin: mechanism Vi-GABA-Tr-In: Quote:
Alkylating agent Bone marrow suppression s/e CML indication Dark skin (hyperpigmentation) s/e Endrocrine insufficiency (adrenal) s/e Fibrosis (pulmonary) s/e
Metabolism enzyme inducers "Randy's Black Car Goes Putt Putt and Smokes": Quote:
Myosis Out of it (sedation) Respiratory depression Pneumonia (aspiration) Hypotension Infrequency (constipation, urinary retention) Nausea Emesis
Therapeutic index: formula TILE: Code: TI = LD / ED Zero order kinetics drugs (most common ones) "PEAZ (sounds like pees) out a constant amount": Quote:
Phenytoin Ethanol Aspirin Zero order _ Someone that pees out a constant amount describes zero order kinetics (always the same amount out)
Asthma drugs: leukotriene inhibitor action Quote:
Quote:
Picture diabetic and asthmatic kids riding away on a cart that rolls on pinwheels. Pindolol and Carteolol have high and moderate ISA respectively, making them acceptable for use in some diabetics or asthmatics despite the fact that they are non-seletive beta blockers.
Beta-blockers: main contraindications, cautions ABCDE: Quote:
D...deoxy barbiturates B...barbiturates H....hydantoin A.. aliphatic carb acids I....iminostilbenes S....succinimides B....BZD's N.... newer drugs P....Phenyltriazines C... cyclic gaba analogues
adverse effects of tetracyclins-KAPIL DEV Quote:
K kidney toxicity A antianabolic effect P phototoxicity I inc ICP L liver toxicity D diabetes insipidus E enamel problems V vestibular toxicity
GENERAL TOXICITY OF ANTICANCER DRUGS SHaLi's BF Ghoghari Gautam is Chor. Quote:
S-skin H-hyperurecemia L-lymphoreticular tissue B-bone marrow F-Foetus G-gonads G-git C-carcinogenecity
6 H s and 8 H s of adverse effects of thaizide diuretics and loop diuretics respectively..... 'melbourne cricket authority has high funds though players get minor amount' .. for clinical uses of beta blockers... Drugs causing pulmonary fibrosis: Quote:
ADRS OF CHLORAMPHENICOL smart boys in girls hostel B.... bone marrow depression H...hypersensitivity I....irritative effects S.....superinfections G.....Gray baby syndrome ampicillin uses UR GMCS BeST Quote:
UTI Respi Gonorrhoea Maningitis cholecystitis septicemias bacillary dysentry sabe typhoid
misch Acyclovir I see clover I see a three-leaf clover (this is a prodrug that gets converted into a triphosphate it resembles dNTP and inhibits DNA Polymerase). Imagine putting clovers over herpes sores and genital warts (this is used to treat those). Amantadine Homan to Dean In case you havent heard, Dr. Homan is our new SOM dean. His new policy: he wont let us come to school without our white coats (this drug blocks uncoating, stage 2, in viral infection). Other interesting facts about him: he can pee for 12 hours straight! (The half-life is 12h and its excreted unchanged in the kidney .) Dr. Homan cant take the pressure of being a new dean so he becomes a nervous drunk with depression, feelings of detachment, insomnia, dizziness, ataxia, slurred speech, and inability to concentrate (these are some of the adverse effects) Cephachlor Chlorine as in swimming pools You swim and get water up your nose and in your ears (this drug treats sinusitis and OTITIS media). Cephadroxil Drop rocks While you are peeing you drop rocks (This drug treats UTIs). Cephalothin Loathing If your heart is infected, you cant love, only loathe (this is used to treat severe infections such as endocarditis). Cephamandole Man doll You have to inflate your man doll and you get an upper respiratory infection. If you use this anatomically correct man doll, he will give you pelvic inflammatory disease (This drug is indicated for URI and PID). Hes also so real that he bleeds!!! (Adverse effect: It affects Vit-K dependent clotting function)
Cephazolin Soul in You want to keep your soul in and not die if you go to surgery (this drug is used prophylactically for surgery). Cephoperazone Opera zone Going to the opera makes me want to get drunk to the point of illness. These drugs, when mixed with ethanol interfere with ALDH, affecting alcohol metabolism (you end up with increased acetaldehyde a DISULFIRAM-LIKE REACTION). Also, if you see Phantom of the Opera, expect to see some blood! (This affects Vit-K dependent clotting function.) Cephotaxime Tax time IRS is hard to kill off they are MULTIPLE DRUG RESISTANT (Use this drug against MDR strains.). Clindamycin Clean the mice Youre cleaning the mice because they are covered with ticks (this drug is used to treat Lyme Disease). You have to use SOS kitchen cleaner to clean the mice (SOS = 50 S ribosomal unit where this drug acts). Richard Gere likes to put mice in where the sun dont shine and this is a very FRAGILE procedure (Clindamycin may cause Pseudomembranous enterocolitis and its also used to treat B. fragilis infections). Fluconazole Flu cone Imagine an emaciated AIDS patient eating an ice cream cone made of the flu and he gets an oral and esophageal fungal infection. (This is used to treat oral and esophageal candidiasis in AIDS patients). Foscarnet Fox cARRR net If you catch foxes in a net, they wont reproduce (this drug is a stage 3 inhibitor). ARRR it inhibits RNA polymerase and Reverse transcriptase to block Reproduction. Youre going to put the foxes into a car thats made out of bones instead of metal (this drug binds to bones and decreases Ca2+ and Mg2+). Also, a foxy lady is HOT (this drug will cause a fever) and never wear fox urine to hunt (this is excreted in the kidney and causes renal insufficiency). inhalational corticosteroids Bed Bug Flew To Florida Quote:
Succinylcholine gets Stuck to Ach receptor, then Sucks ions in through open pore. You Suck stuff in through a mouth-tube, and drug is used for intubation
Cholinergics (eg organophosphates): effects If you know these, you will be "LESS DUMB":
Quote:
Lacrimation Excitation of nicotinic synapses Salivation Sweating Diarrhea Urination Micturition Bronchoconstriction
Steroids: side effects BECLOMETHASONE: Quote:
Buffalo hump Easy bruising Cataracts Larger appetite Obesity Moonface Euphoria Thin arms & legs Hypertension/ Hyperglycaemia Avascular necrosis of femoral head Skin thinning Osteoporosis Negative nitrogen balance Emotional liability
Methyldopa: side effects METHYLDOPA: Quote:
Mental retardation Electrolyte imbalance Tolerance Headache/ Hepatotoxicity psYcological upset Lactation in female Dry mouth Oedema Parkinsonism Anaemia (haemolytic)
Sodium valproate: side effects VALPROATE: Quote:
Vomiting Alopecia
Liver toxicity Pancreatitis/ Pancytopenia Retention of fats (weight gain) Oedema (peripheral oedema) Appetite increase Tremor Enzyme inducer (liver)
Captopril (an ACE inhibitor): side effects CAPTOPRIL: Quote:
Cough Angioedema/ Agranulocystosis Proteinuria/ Potassium excess Taste changes Orthostatic hypotension Pregnancy contraindication/ Pancreatitis/ Pressure drop (first dose hypertension) Renal failure (and renal artery stenosis contraindication)/ Rash Indomethacin inhibition Leukopenia/ Liver toxicity
Lithium: side effects LITH: Quote:
Bradycardia & hypotension Anorexia Diminished pupilary size Analgesics Miosis Euphoria Respiratory depression Increased smooth muscle activity (biliary tract constriction) Constipation Ameliorate cough reflex Nausea and vomiting Sedations
Ca++ channel blockers: uses CA++ MASH: Quote:
Cerebral vasospasm/ CHF Angina Migranes Atrial flutter, fibrillation Supraventricular tachycardia Hypertension
Reserpine action Reserpine depletes the Reserves of catecholamines [and serotonin] Sodium channel blockade: Procainamide, Quinidine, Disopyramide "Quaker Preachers Discussed Sobriety."
Quaker-Quinidine Preachers-Procainamide Discussed-Disopyramide Sobriety-Sodium channel blockade
Class IB - Sodium channel blockade: Lidocaine, Phenytoin, Mexiletine, tocainide "Philadelphians Like Salty Mexican Tacos."
Class IC - Sodium channel blockade: Flecainide, Encainide, Propafenone "Flea Encrusted Prophets."
Flea-Flecainide Encrusted-Encainide Prophets-Propafenone
Class III - Prolong repolarization: Amiodarone, Bretylium, Solatol "Britain Repossessed American Soaps."
Britain-Bretylium Repossessed-Repolarization is prolonged. American-Amiodarone Soaps-Solatol
Antiarrhythmic agents:
"A Dubious Quality Product... Bought To Preserve Little Money... Can Fabricate Enough Problems." A-1a B-1b C-1c
1a-A:
D-Disopyramide Q-Quinidine P-Procainamide 1b-B: T-Tocainamide P-Phenytoin L-Lidocaine M-Mexiletine 1c-C: F-Flecainamide E-Encainamide P-Propafenone
DUMB BELS
Diarrhoea, Urination, Miosis / muscle weakness, bronchorrea Bradycardia, emesis, lacrimation, salivation / sweating
Heartburn Cataract, Osteoporosis, Muscle weakness, Path # / Psychosis, Acne / Altered Glucose, Cushingoid, Thin skin Increased appetite, Myopathy, poor wound healing, stress response reduced
AM CUSHINGOID
Acne, Myopathy (prox) / muscle wasting (prox) Cushingoid / Cataract, Ulcers, Striae, skin thin (bruising), Hypertension / hairy, Infection, Glycosuria, Obesity / Osteoporosis / Oedema, Immunosuppression / Insomnia, Depression
Pathology Mnemonics
MI: post-MI complications ACT RAPID:
Arrhythmias (SVT, VT, VF) Congestive cardiac failure Tamponade/ Thromboembolic disorders Rupture (ventricle, septum, papillary muscle) Aneurysm (ventricle) Pericarditis Infaction (a second one) Death/ Dressler's syndrome
MI: complications
HAS CRAPPED:
Heart failure/ Hypertension Arrhythmia Shock Cardiac Rupture Aneurysm Pericarditis Pulmonary Emboli DVT
PARIS:
Post-streptococcal
Alport's RPGN IgA nephropathy SLE Alternatively: PIG ARMS to include Goodpasture's [one cause of RPGN], Membranoproliferative [only sometimes included in the classic nephritic list].
Anemia: TIBC finding to differentiate iron deficiency vs. chronic disease Quote:
FAT RBC:
Fetus (pregnancy) Alcohol Thyroid disease(ie hypothyroidism) Reticulocytosis B12 and folate deficiency Cirrhosis and chronic liver disease
TIMID CHIMP:
Tetany Increases paralytic ileus (aggravates) Muscle weakness Increases possibility of hepatic encephalopathy Digoxin toxicity Cardiac arrythmias Hypotonia Increases P-R interval, T wave and prominent U wave Muscle cramps Polyuria
Cardiopulmonary
-atherosclerosis -CHF -hypertension -pericarditis
Feverous infections
-due to leukocyte abnormalities and dialysis hazards
GI disturbances
-haemorrhagic gastritis -peptic ulcer disease -intractable hiccups
MAD SCAB:
Mycotic Atherosclerotic Dissecting Syphilitic Capillary microaneurysm Arteriovenous fistula Berry
Necrosis: the 4 types Code: "Life Can Get Complicated": Liquifactive Coagulation Gangrene Caseous 'Life' used since necrosis is 'death'.
Turner syndrome: components Code: CLOWNS: Cardiac abnormalities (specifically Coartication) Lymphoedema Ovaries underdeveloped (causing sterility, amenorrhea) Webbed neck Nipples widely spaced Short
Fragile-X syndrome: features Code: DSM-4: Discontinued chromosome staining Shows anticipation Male (male more affected) Mental retardation (2nd most common genetic cause) Macrognathia Macroorchidism Whipple's disease: full features Code: WHIPPLES: Weight loss Hyperpigmentation of skin Infection with tropheryma whippelii
CREST sydrome: components Code: CREST: Calcinosis Raynaud's phenomena Esophageal dysmotility Sclerodactyly Telangectasia
Edwards' syndrome: characteristics Code: EDWARDS: Eighteen (trisomy) Digit overlapping flexion Wide head Absent intellect (mentally retarded) Rocker-bottom feet Diseased heart Small lower jaw
Fragile X syndrome: features Code: FEMALES FMR1 gene Exhibits anticpation Macro-orchidism Autism Long face with large jaw Everted eyes
Generalized rash: rash dots. Cervical lymphadenitis: enlarged cervical nodes with inflammation arrows. Vasculitis of arteries: inflammation arrows on arteries. Cardiovascular sequelae [20%]: inflammation arrows on cardiac arteries. Treat with aspirin: aspirin headlight.
Kawasaki disease: diagnostic criteria CHILD: 5 letters=5 days, >5 years old, 5 out 6 criteria for diagnosis:
Conjuctivitis (bilateral)
Hyperthermia (fever) >5 days Idiopathic polymorphic rash Lymphoadenopathy (cervical) Dryness & redness of (i)lips & month (ii)palms & soles [2 separate criteria]
Physiology Mnemonics
Cochlea: inner vs. outer hair cell function Quote:
"Outer cells are Out of the brain. Inner cells are Into the brain":
Outer hair cells are motor efferents to amplify signal. Inner hair cells are sensory afferents that actually pick up the sound.
FLAGTOP:
Follicle stimulating hormone Lutinizing hormone Adrenocorticotropin hormone Growth hormone Thyroid stimulating hormone Oxytocin Prolactin
Alternatively: GOAT FLAP with the second 'A' for Anti-diruetic homone/vasopressin Note: there is also melanocyte secreting homone and Lipotropin, but they are not well understood.
Adrenal cortex layers and products Quote:
TRIPS BIAS:
TRIcuspid Pulmonary Semilunar BIcuspid Aortic Semilunar
COMPLIANCE:
Collagen deposition (fibrosis) Ossification of costal cartilages Major obesity Pulmonary venous congestion Lung size Increased expanding pressure Age No surfactant Chest wall scarring Emphysema All but L/A/E decrease compliance.
PROGESTE:
Produce cervical mucous Relax uterine smooth muscle Oxycotin sensitivity down Gonadotropin [FSH, LH] secretions down Endometrial spiral arteries and secretions up Sustain pregnancy Temperature up / Tit development Excitability of myometrium down
THYROIDISM:
Tremor Heart rate up Yawning [fatigability] Restlessness Oligomenorrhea & amenorrhea Intolerance to heat Diarrhea Irritability Sweating Musle wasting & weight loss
OESTROGEN SUX:
Organ development (sex organs) Endocrine: FSH and LH regulation Secondary sex characteristics development Tropic for pregnancy Receptor synthesis (of progesterone, oestrogen, LH) Osteoporosis decrease (inhibits bone reabsorption) Granulosa cell development Endocrine: increases prolactin secretion, but then blocks its effect Nipple development Sex drive increase Uterine contractility increase oXytocin sensitivity increase
Quote:
Acidophilic: GPA: Growth hormone Prolactin Acidophilic Basophilic: B-FLAT Basophilic FSH LH ACTH TSH
Quote:
Alternatively: "Nine Little Monkeys Eating Bananas". Alternatively: "Noone Likes My Educational Background". Alternatively: "Never Let Mamma Eat Beans".
Alternatively: Granpa BEN..." to keep the granulated group straight. Mast cell primary granule contents Quote:
Basophils are "Bad-o-phils" because they contribute to our allergic reactions. Eosinophils are "Easy-on-me-phils" because they counteract our allergic reactions.
Muscle sarcomere: A vs. I as light or dark Quote:
There is only one vowel in "dark" and one vowel in "light". These one vowels match up to their one letter names:
DArk band is the A band. LIght band is the I band.
HAZI (Hazy):
H line is in A-band. Z disc is in the I band.
ABCDEF:
Alcohol + liver disease B12 deficiency Compensatory reticulocytosis (blood loss and hemolysis) Drug (cytotoxic and AZT)/ Dysplasia (marrow problems) Endocrine (hypothyroidism) Folate deficieny/ Fetus (pregnancy)
"Al-K-loss, Al-Ca-loss":
There is loss of K+ (hypokalemia) and Ca++ (hypocalcemia) in state of alkalosis.
"ABC" of glycosylated Hb (Hb1c): Glucose binds to Amino terminal of Beta Chain . "HbF binds Forcefully": HbF binds oxygen more forcefully than HbA, so Oxy-Hb dissociation curve shifts to left. Stored blood is SOS: Stored blood Hb binds to Oxygen Strongly because of decrease in 2,3 BPG. 2,3 BPG binding site is BBC: BPG binds to Beta Chain of Hb. Myoglobin binding strength is MOM: Myoglobin binds Oxygen More strongly than Hb.
Intrinsic vs. extrinsic pathway tests Quote:
"PeT PiTTbull": PeT: PT is for extrinsic pathway. PiTTbull: PTT is for intrinsic pathway.
Carotid sinus vs. carotid body function Quote:
FLATPiG:
FSH LH ACTH TSH Prolactin ignore GH
COMPLIANCE:
Collagen deposition (fibrosis) Ossification of costal cartilages Major obesity Pulmonary venous congestion Lung size Increased expanding pressure Age No surfactant Chest wall scarring Emphysema
Quote:
ROME:
Respiratory= Opposite: pH is high, PCO2 is down (Alkalosis). pH is low, PCO2 is up (Acidosis). Metabolic= Equal: pH is high, HCO3 is high (Alkalosis). pH is low, HCO3 is low (Acidosis)