Pharmacology 2nd

Assessment

Confidential

Done by:

Tifaree’3 2003
 Pharmacology 2nd assessment

1) What is incorrect?
E- It doesn’t cause vasodilatation & reduce vascular resistance

2) One of the following is angiotensin receptor blocker:

B- Valsartan

3) 150/95, diabetic, proteinuria. What is the ideal treatment?

C- ACE inhibitor

The following questions (4-6) refer to the figure on the right

A-phase 0 1
B- Phase 1 2
C- Phase 2
D- Phase 3 0
E- Phase 4 3
4

4) Drugs interfering with this phase reduce conduction through AV node & reduce
pacemaker activity of SA node

5) Inhibition of K+ efflux drug in this phase delays repolarization

6) All antiarrythemia agents interferes with this phase

7) First generation antihistamines can prevent sneezing accompanied with allergic

rhinitis mainly by:
E- Blocking H1 receptors on nasal sensory nerve endings

8) Which of the following is correct about ecosanoids?

E- They are all products arachidonic acid

A: 1,2,3 B:1,3 C:2,4 D:4 E: all correct

9) Nicotinic acid:
1- Inhibit lipolysis in adipose tissue
3- Increase activity of lipoprotein lipase

10) Lovastation:
1- Acts by inhibiting activity of HMG-COA reductase
2- Prolonged treatment leads to increase serum transminases
3- May be beneficial in non lipidemic patient with cardiac hypertrophy
4- Improves endothelium dependent vasodilatation
11) Which of the following is/are correct?
1-Anticogulant effect of warfarin is slow in onset
2-About 95% of warfarin is free in plasma
3-Bleeding associated with warfarin over dose can be treated with Vitamin K supplement
4- Warfarin is used in blood banks to prevent stored blood from clotting.

12) Aspirin differs from other NSAID by:

1- Effective action only on platelets
2- Effective at very low doses
3- able to induce gastric erosion & ulceration
4- Irreversibly inactivating the cyclo oxygenase enzyme

13) The usefulness of aspirin in prophylaxis & treatment of myocardial infarction:

4- anti platelets action

14) What is correct about B blocker?

1- Reducing cardiac output by blocking cardiac B1 adrenergic receptor
2- Reducing rennin release by blocking renal B1 adrenergic receptor
3- Can be given as first line drug to hypertensive patient

15) Ahmed is a hypertensive patient with a blood pressure of 170/105 mmHg. Which
of the following regimens should be recommended:

4- Diuretics + B- blockers

Answers:

1. E 9. B
2. B 10.E
3. C 11.B
4. C 12.D
5. D 13.D
6. E 14.A
7. E 15.D
8. E