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Cob A Lamina

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Cobalamina ( vitamina B12)

Bote Andreea Oana CATB,II

Cobalaminele sunt compusi ai ligantului corina cu ionul cobalt (III)hexacoordinat, legat ecuatorial de patru atomi de azot ai acestuia ; Ruda a hemoglobinei cu centru de Co in loc de Fe Porfirina este deformata la capete Au atasate si o nucleotida

Cobalamina contine o legatura reactiva C-Co, care participa la doua tipuri de reactii catalizate de enzime: Rearanjamente in care un atom de H este transferat direct intre doi atomi adiacenti concomitent cu schimbul unui alt substituent Transferul de grupari metil intre doua molecule

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