M 39, scalp nodule, 3 cm

Deba P Sarma, MD, Omaha

M 39, scalp nodule, 3 cm

Diagnosis: Cylindroma Comment: Clinical: Sex: mostly female. Location: mostly scalp. Slow-growing, sometimes painful solitary pink or red dermal nodule averaging 1 cm in size. Familial cases are associated with multiple tumors. Such cases may also be associated with facial trichoepitheliomas, and eccrine spiradenomas, called autosomal dominant Brooke-Spiegler syndrome (familial cylindromatosis or turban tumor syndrome).

Pathologic features: -Presence of numerous scalp lesions is called turban tumor.

-Non-encapsulated dermal tumor not connected to the overlying epidermis.

-Composed of numerous lobules of epithelial cells arranged in a jigsaw

or mosaic pattern.

-Prominent red basement membrane-like structure encircles the tumor lobules.

-Each lobule shows a peripheral lining by dark basaloid cells and an inner

larger and paler zone of cells.

-Nodular deposits of red material within the lobules as well as focal well-formed ducts.

-This is a common adnexal tumor of eccrine origin.