update XXOIC_OE_QUOTE_LINES_ALL set ITEM_DESCRIPTION= replace(ITEM_DESCRIPTION,

substr((TRANSLATE(upper(ITEM_DESCRIPTION),
CHR (0)
|| 'QWERTYUIOPASDFGHJKLZXCVBNM ,.<>/?;:''"[{]}1234567890-=!@#$%^&*()_+\|`~',
CHR (0))),1,1)) where TRANSLATE
(UPPER (ITEM_DESCRIPTION),
CHR (0)
|| 'QWERTYUIOPASDFGHJKLZXCVBNM ,.<>/?;:''"[{]}1234567890-=!@#$%^&*()_+\|`~',
CHR (0)
) IS NOT NULL

================================
SELECT line_number,QUOTE_NUMBER,ITEM_TYPE_CODE,ITEM_DESCRIPTION
FROM XXOIC_OE_QUOTE_LINES_ALL
WHERE TRANSLATE
(UPPER (ITEM_DESCRIPTION),
CHR (0)
|| 'QWERTYUIOPASDFGHJKLZXCVBNM ,.<>/?;:''"[{]}1234567890-=!@#$%^&*()_+\|`~',
CHR (0)
) IS NOT NULL --and QUOTE_NUMBER='QUT-1533/2012'
order by QUOTE_NUMBER,line_number