Drug Study Drug Name Generic Name: Oxacillin Therapeu tic Action Indicatio n Systemic infections caused by penicillinas

eproducing staphyloco cci specifically eye infections Side Effects/ Adverse Effects Contraindic fever, so ated to re patients throat, hypersensi and hea tive to dache wi drug and th a its severe contents blisterin g, peeling, and red skinrash ;diarrhe a that is watery or bloody; fever, chills, body aches, flu sympto ms;easy bruising or bleeding , unusual weaknes s; urinatin g less than usual or not at all; Contraind ication Nursing Responsi bilities Use cautiousl y in patients with other drug allergy, especially to cephalos porins. Obtain specimen for culture and sensitivity tests before first dose. Give 1-2 hours before or 2-3 hours after meals to prevent gastric irritation.

A penicillinas e resistant Classificat penicillin ion: that Penicillin inhibits cell-wall Dosage: synthesis during microorgan ism multiplicati on; bacteria resists penicillins by producing penicilllina se enzymes that convert penicillins to inactivate penecillic acids. Oxacillin resists these enzymes.

severe skin rash, itching, or peeling; agitation , confusio n, unusual thoughts or behavior ; or seizure.

Drug Name Generic Name: Chloramph enicol

Therapeu tic Action

Indicatio n Ocular infection

Contraind ication History of hypersensi tivity or toxic reaction to the drug.

Chloramph enicol is a bacteriosta tic drug that stops Classificat bacterial ion: growth by Antiinhibiting infective protein synthesis. Dosage: Chloramph 0.5% enicol solution: prevents Instill 1-2 protein drops chain hourly, elongation then adjust by dosage inihibiting interval the upon peptidyl

Side Effects/ Adverse Effects GI symptoms; bleeding; peripheral and optic neuritis, visual impairmen t, blindness; encephalop athy, confusion, delirium, mental depression , headache. Haemolysis in patients

Nursing Responsi bilities Assess culture infection before beginnin g therapy Monitor hematolo gic data Monitor serum levels periodica lly Advice patient that she

improveme transferase nt. activity of the bacterial ribosome.

with G6PD deficiency. ophthalmic application : Hypersensi tivity reactions including rashes, fever and angioedem a. Ear drops: Ototoxicity . Potentiall y Fatal: Bon e marrow suppressio n and irreversible aplastic anaemia. Neutropeni a, thrombocy topenia. Grey baby syndrome. Rarely, anaphylaxi s. Indicatio n Ocular infection Contraind ication Patients hypersensi tive to drug. Side Effects/ Adverse Effects Some burning, stinging, irritation,

may experien ce side effects such as nausea, vomiting , diarrhea, headach e

Drug Name Generic Name: Tobradex (tobramyci

Therapeu tic Action Tobradex works by binding to a site on

Nursing Responsi bilities Ophthalmic solution Instruct patient

n and dexametha sone ophthalmic suspension )

the bacterial 3 0S and 50 S ribosome , preventing formation Classificat of the 70S ion: complex. Aminoglyc As a oside result, mR NA cannot Dosage: betranslate ophthalmic d into ointment protein 3 mg/g and cell death ensues.

itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.

to tilt head back; place medicatio n into conju nctival sa c, and close eye; apply light finger pressure on lacrim al sac for 1 min. Solution may cause blurring of vision or stinging on administr ation. Instruct patient to report severe stinging, itching, or burning.