NURS 1566 Clinical Form 3: Clinical Medications Worksheets

(You will need to make additional copies of these forms)

Generic Name Trade Name Classification Dose Route Time/frequency

Piperacillin/ Zosyn Anti-infectives 3.375 mg IV Q 8 Hours
tazobactam
Peak Onset Duration Normal dosage range 3.375 g q 6 hr.
End of infusion Rapid 4-6 hr Renal impairment (CCr < 40 ml/min)

Why is your patient getting this medication For IV meds, compatibility with IV drips and/or solutions
peritonitis

Mechanism of action and indications (Why med ordered) – Akin and
skin structure infections, gynecologic infections. Community-
acquired and nosocomial pneumonia caused by peperacillin-
resistant, beta-lactamase-producing bacteria. Piperacillin binds to
bacterial cell wall membrane, causing cell death. Spectrum is
extended compared with other penicillins. Taxobactam inhibits beta-
lactamase, an enzyme that can destroy penicillins. Death of
susceptible bacteria.
Nursing Implications (what to focus on)
Contraindications/warnings/interactions
Hypersensitivity to penicillins, beta-lactams, cephalosporins, or
tazobactam. Cautiously in renal impairment dosage 40 ml/min.
Common side effects – seizures, pseudomembranous colitis,
diarrhea, rashes, pain, phlebitis, anaphylazis, serum sickness

Interactions with other patient drugs, OTC or herbal medicines (ask
patient specifically) Lasix, corticosteriods
Nursing Process- Assessment
(Pre-administration assessment)
Infection, VS, appearance of wound, sputum, urine,
and stool, WBC.
Lab value alterations caused by medicine – May increase BUN,
creatinine, AST, ALT, serum bilirubin, alkaline phosphatase and
LDH. Leukopenia and neutropenia in hepatic impairment.
Be sure to teach the patient the following about this medication
Report signs of superinfection (black furry tongue, vaginal itching
or discharge, loose or foul-smelling stools and allergy. Call Dr. if
fever or diarrhea occur especially if it contains blood, pus or musus.
Assessment Evaluation
Why would you hold or not give this med? Check after giving
superinfection (black furry tongue, vaginal Resolution of s/s of infection.
itching or discharge, loose or foul-smelling Length of time for complete
stools and allergy. Anaphylaxis (rash, puritus., resolution depends on the
laryngeal edema, wheezing. organism and site of infection