MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

PRACTICAL PATHOLOGY 4: CANCER COLON

A)Jars:Organ: Part of the large intestine Description: A large submucous tumour is bulging into the lumen of the intestine. The tumour: Is ovoid in shape Has smooth external surface Has a short narrow pedicle Cut surface is whorly in appearance Diagnosis: Myoma

ACE 2013/14

MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

Organ: Part of the large intestine Description: The ileocaecal junction is infiltrated by a large non-encapsulated grayish white, ill defined hard mass with focal translucent areas of jelly like material The tumour has invaded the wall of the caecum and sent similar tumour deposits to the draining lymph nodes Diagnosis: Mucoid carcinoma of the colon

ACE 2013/14

MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

Organ : Part of the large intestine Description: Segment of the left colon shows an ill defined grayish white nonencapsulated tumour invading the wall of the colon circumferentially causing its constriction in a purse string like pattern. The tumour is hard in consistency Diagnosis: Annular carcinoma of the left colon

ACE 2013/14

MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

Organ: Part of the large intestine Description: A large ovoid ulcerative mass is seen. The ulcer is Solitary Size: large Outline: Irregular Edge: raised and everted Floor: covered by blood clots and necrotic debris Base: hard, fixed and indurated

Diagnosis: Ulcerative carcinoma of rectum

ACE 2013/14

MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

Organ: Part of the large intestine Description: A solitary, large, fungating polypoidal mass projecting into the lumen Colour of the mass: grayish white Consistency: firm Diagnosis: fungating carcinoma of the lower rectum.

ACE 2013/14

MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

B) Slides :Adenocarcinoma, colon: Part of the colonic wall showing: Focal mucosal ulceration The submucosa and muscle coat are by infiltrated by carcinomatous cells arranged in glandular formations of different sizes and shapes The tumour cells are mostly columnar and show large hyperchromatic nuclei Mitotic figures are detected

ACE 2013/14

MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

ACE 2013/14

MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

Mucoid carcinoma, colon Part of the colonic wall showing. Focal mucosal ulceration Infiltration of the submucosa as well as part of the muscuosa by clusters and masses as well as occasional tubular formations of carcinomatous cells showing large hyperchromatic nuclei and scant cytoplasm. Mitotic figures are detected The tumour cells area seen within abundant mucous pools.

ACE 2013/14

MODULE 18 GASTROINTESTINAL TRACT (PATHOLOGY)

ACE 2013/14