Fluids and Electrolytes, Metabolism and Endocrine (NCM103) Cardiovascular System: Coronary Vascular Disease
Coronary Atherosclerosis Definition: Abnormal accumulation of fatty substances Creates BLOCKAGE Repetitious inflammatory response o Obstruction + Inflammation = Blood Flow MI or AP
Atherosclerosis Arteriosclerosis 1. Definition Lumen Lumen 2. Cause Deposition of fatty substances Elasticity of blood vessels 3. Age Toddlers Aging process 4. Layer Tunica intima Tunica media
Risk Factors: Blood lipid level Smoking lumen; vasoconstriction Hypertension Narrowing down of blood vessels Diabetes / Hyperlipidemia Obesity Metabolic Syndrome o Hyperglycemia FBS, Glucose Tolerance Test o Hypertension o Level of lipids in blood o Presence of elevation CRP
Clinical Manifestations: - Depends on 1. Location and degree of narrowing 2. Thrombus formation and obstruction of blood CHEST PAIN~ Asymptomatic~
Prevention: Control of cholesterol level Get lipid profile once ever 5 years (20 y/o and above) a. Diet b. Physical Activity c. Medications Anti-lipid Drugs d. Promoting cessation of tobacco Nicotine!! Viscosity of blood Vasoconstric tion of Blood Vessels e. Managing Hypertension Religious intake of DRUGS Regular exercise Diet Alcohol intake Topics Discussed Here Are: 1. Coronary Atherosclerosis 2. Angina Pectoris 3. Myocardial Infarction LOOKY HERE
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NUTRIENT CONTENT OF THE THERAPEUTIC LIFESTYLE CHANGES (TLC) DIET Nutrient Recommended Intake Total calories Balance intake and expenditure to maintain desirable weight Total fat Saturated fat Polyunsaturated fat Monounsaturated fat 25% - 35% of total calories Less than 7% of total calories Up to 10% of total calories Up to 20% of total calories Carbohydrate 50% - 60% of total calories Dietary fiber 20 30 g/day Protein Approximately 15% of total calories Cholesterol Less than 200 mg/day
Angina Pectoris Factors: Blood Flow due to Lumen Non-modifiable Factors 1. Age 2. Sex 3. Race 4. Family History
Coronary Insufficiency Coronary occlusion (Continuation of coronary insufficiency) Lumen CHEST PAIN On and Off Bearable Short Duration Angina Pectoris CONSTANT SEVERE LONGER Myocardial Infarction Ischemia
Types of Angina Pectoris 1. Stable Angina ` Predictable and consistent pain ` Relieved by rest and / nitroglycerin 2. Unstable Angina / Preinfarction Angina / Crescendo Angina ` Symptoms increase in frequency ` May not be relieved by rest and nitroglycerin 3. Variant Angina (Prinzmetals Angina) ` Pain at rest ` Reversible ST-segment elevation 4. Silent Ischemia ` Objective evidence of ischemia ` But NO PAIN :o
Management: 1. Medical Management a. Rest Minimum of 2 hours
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b. Drugs 1. Coronary Vasodilators O Dilates lumen of blood vessels in the myocardium O Drugs: o Nitroglycerin + 1 Tab, SL q5 min PRN for chest pain + Maximum of 3 Tablets; if not resolved considered MI + Take the medications before any stressful event + Loses potency when exposed in the sun; store in dark colored bottles + If head gets big, warm, and flushing of face it is NORMAL, not SIDE EFFECT or ADVERSE EFFECT 2. Anti-platelet Drugs O Aspirin (Produces GIT disturbance; Coated Aspirin New) O Heparin o Side Effect = Bleeding (Petechiae, Ecchymosis, Hematoma) o WOF: Tea colored urine for HEMATURIA o WOF: BLACK STOOLS O NO PARENTERAL ADMINISTRATION OF DRUGS; if needed, apply pressure after!! O Dont use dental floss 3. Beta Blockers To reduce O 2 demand of myocardium 4. Ca + Channel Blocking Agent Relaxes the Blood Vessel to BP c. Take 30 60 cc of BRANDY/WHISKY To reduce chest pain by vasodilation Amount = Vasoconstriction Amount = Vasodilation
2. Prevention of Succeeding Attacks to Angina Pectoris a. Diet Fat Diet (THE FOLLOWING FOODS ARE NOT ALLOWED OR MODERATE) - 4 Legged animals - Foods with wings (Moderate) - White meat - Chicken (NO SKIN) - Intake of food in WATER; but grows in SOIL Na Diet (2 gm Na) AVOID THE FF FOODS 1. Na Nitrate Food colorings, cold cuts, preserved food 2. Na Nitrite Tocino, Tapa 3. Na HCO 3 Baking Soda, bread, biscuit, pastries 8:00 1 st Tablet 8:05 2 nd Tablet 8:10 3 rd Tablet 8:00 1 st Tablet 8:05 2 nd Tablet 3:30 1 st Tablet
jcmendiola_Achievers2013 4. NaCl Fish sauce, soy sauce, dried fish 5. Na Saccharin b. Must be with the patient all the time!! Coronary Vasodilators - DONT EXPOSE IN THE SUN!! - DONT LEAVE IN THE CAR!!
Myocardial Infarction Brought about by lack of blood supply going to the myocardium A.k.a. Coronary occlusion or Heart Attack
Pain: - CRUSHING - TIGHTNESS - Sudden onset - Substernal - Severe - Unrelieved by Nitroglycerin - May radiate to: Back, neck, jaw, shoulders, arm - Dyspnea - Syncope ( BP) - Nausea / Vomiting - Extreme weakness - Diaphoresis - Denial is common - HR Treatment: - O2 IV Medications - Dietary restrictions - Na, Cholesterol, Caffeine - Surgery? Pacemaker?
Causes: 1. Atheroma Associated with body metabolism 2. O 2 / Blood demand Patients with hyperthyroidism 3. O 2 Supply (Anemia, BP) 4. Vasospasm Sudden constriction / narrowing of coronary arteries
How to Diagnose Clients With MI 1. Presenting Manifestations ` Chief complaint ` Previous illnesses ` ECG: Done in 10 minutes PRIOR to admission
P Q R S T ANG HIRAP MAG DROWING NG ECG PQRST SA PC XD Components 1. P Wave Atrial Contraction / Depolarization (0.08 seconds) 2. PR Interval Time for impulses to travel from Artery to Ventricle (0.16 seconds) 3. QRS Complex Ventricular Contraction / Depolarization (0.08 seconds) 4. ST Segment Length of time for the ventricle to relax (0.12 seconds) 5. T Wave Ventricular relaxation / Repolarization (0.16 seconds)
0.08 seconds 2 seconds
jcmendiola_Achievers2013 Diagnosing Myocardial Infarction Inverted T Wave + Injury becomes ischemic, myocardial Repolarization is altered and delayed + Which causes the T Wave to invert Elevated ST-segment + Injured myocardial cells depolarize normally, but repolarize more rapidly than normal cells + Causing the ST-segment to rise at least 1 mm above the isoelectric line Laboratory Results + Creatinine Kinase (CK-MB) + Lactic Dehydrogenase + Myoglobin + Troponin T and I
Management 1. Minimize Myocardial damage a. Cardiac overload Place patient on absolute bed rest - NO VISITORS ALLOWED (NEAREST RELATIVE ONLY) - Health team should be calm b. Get baseline Vital Signs TPR - Temperature = Due to cell death - Pulse = - Respiration = - Blood Pressure = Baseline ECG Basic serum electrolytes c. Administration of Drugs Thrombolytic Drugs (Alteplase) - 1 st Drug - To dissolve the blood clot - The faster it is given, it is better Analgesics - To relieve chest pain - Morphine - Pain and Anxiety related to MI ACE Inhibitors - To prevent BP 2. Cardiac Rehabilitation Main objective: To extend the life of the patient and improve the quality of life of patients Consists of different activities
3 Phases of Cardiac Rehabilitation 1. Phase I Time of diagnosis of atherosclerosis Found out by lipid profile Management: - Preventive measures 1. Level of activities (Walking) 2. Initial education of patient and family (For self care) 3. Quit Smoking! 4. DIET > NO FATTY FOODS If patient is not compliant, there would be repeated attacks of angina pectoris and myocardial infarction .
jcmendiola_Achievers2013 2. Phase II _ Time the patient has been discharged from the hospital _ All activities are supervised; support from an outside person _ Based on the stress test of the client _ Dietitian would make a list of foods to be eaten and not eaten 3. Phase III e Maintain cardiovascular stability e Patient can still be on diet and exercise, but no longer supervised
Reperfusion Therapy - Procedures wherein to further improve the blood flow to the myocardium such as: o Angioplasty: Repair of blood vessel PTA (Percutaneous Transluminal Angioplasty) PTCA (Percutaneous Transluminal Coronary Angioplasty) It is the inflation of a balloon pushing atheromas to the side, done not to attain 100% o Coronary Stent Inserted through the femur Placement of a spring Can cause thrombus formation But eventually becomes part of the endothelial tissue o Atherectomy Removal of atheromas Hollow cylinder Diamond chip-blade Rotation: Scrape atheromas Not full scraping of atheromas o Coronary Artery Bypass Graft (CABG) They cannot perform not until there are still very minimal amount of blood to the myocardium Harvest a Graft Artery Vein o Common blood vessel used Internal mammary artery Saphenous vein
Nursing Care Patient should be VERY compliant + Drugs be taken religiously Thrombolytics Beta blockers Digitalis + Compliance to diet FAT Na + Ambulation Gradually increasing + Sexual Intercourse Patient should be able to make 5 7 steps in the stairs without fatigability