Giving the Nursing Care Plan (NCP) to the people with SLE is quite challenging because the symptoms

and the diagnosis of SLE sufferer is difficult to predict. There is variety of assessment to determine SLE sufferer and they precisely encounter prolonged assessment regarding the difficulties to assess the symptoms. The assessment may include the medical history and physical examination, laboratory tests, and a period of observation that possibly takes several years. There are no single laboratory tests that can prove or disapprove this disease. Initial screening includes a complete blood count (CBC); liver and kidney screening panels; laboratory tests for specific autoantibodies (e.g., antinuclear antibodies [ANA]) such as anti-Ro, anti-La, anti-dsDNA, anti-Sm, anti-RNP, lupus anticoagulant, and anticardiolipin; an antiphospholipid antibody test; urinalysis; blood chemistries; and erythrocyte sedimentation rate (ESR). The result of this test will shown the evidence of existence symptom which will reflect the ongoing disease. The treatment of Lupus embraces the whole aspect of human needs, such biological, psychological, and also social needs. As the health professional, we have to fulfill all of the needs to reduce the symptom of LUPUS. The biological needs will be fulfilled through the prescribed medication. Although there are no medicines that can cure this disease, some medicine are needed to control the symptom and the specific manifestations. Some medicines which used to control the symptom are nonsteroidal anti-inflammatory drugs (NSAIDs), antimalarials, corticosteroids, immunosuppressives, and intravenous immunoglobulins. Health Professional Care has to take care about the kind and the doses of medicine they give to the people with LUPUS. Taking notice for the drug history is needed to assess the allergies, hypersensitivities, and side effects. Beside the medication, treatment for lupus sufferer encompass the physical rest, emotional rest, protection from direct sunlight, diet and nutrition, treatment of infection, surgery, and immunizations. Meanwhile, the psychosocial aspect is also needed to be remarked. For the people with LUPUS, the emotional reaction of dealing with this disease can be overwhelming. Anger, grief, and depression are the common response for the people with LUPUS. The involvement and cooperation of the patient, family, and support system will help the patient to gain the emotional control that will lead into the better condition. By allowing the patient and her or his family the time and freedom to move through different emotional phases without criticism and unrealistic expectation, it will facilitate acceptance of this disease. Nurses and all of health professional care can have a role to help the patient adjust and deal with this disease and help with referrals to a social workers, counselor, community resources, and so forth, if its needed.