1

GRILA DE EVALUARE PRIVIND CONFERIREA TITLULUI DE CONFERENTIAR UNIVERSITAR CRITERIUL 1: ACTIVITATEA DIDACTICA A. CONDITII PRELIMINARE DA Studii universitare de licenta * Studii de masterat ** Studii de doctorat Pozitia Asistent universitar profesionala Sef de lucrari actuala Din afara invatamantului Total punctaj Vechime minima obligatorie Da Nu Da Da Da NU Maxim 3 2 4 1 2 0 PUNCTAJ Autoevaluare 3 4 2 9 Comisie 3 4 2 9

* competente in 1) ecografie (ultrasonografie); 2) hepatologie; 3) managementul serviciilor de sanatate ** nu se aplica in domeniul pentru care candideaza B. CRITERII DE EVALUARE Criterii a. Autoevaluarea activitatii didactice DA NU Da b. Evaluare Din partea colegilor DA NU Da Sef catedra DA Da NU

Experienta profesionala in domeniul pentru care candideaza

Activitati de predare Participari la comisii de concurs - ex. admitere - ex. licenta - ex. Promovare - indrumare de LD Calificativul

Da Da Da Da Da FOARTE BINE

Da Da Da Da Da FOARTE BINE

Da Da Da Da Da FOARTE BINE

CRITERIUL 2: ACTIVITATEA DE CERCETARE IN ULTIMII 5 ANI Da/Nr. Contract/grant international - director Contract/grant international membru in echipa de cercetare Contract/grant national - director Contract/grant national membru in echipa de cercetare Studii multicentrice internationale investigator principal Studii multicentrice internationale membru in echipa de cercetare Studii multicentrice nationale investigator principal Studii multicentrice nationale membru in echipa de cercetare TOTAL PUNCTAJ NU Alocat 20 x Nr 12 x Nr 6 x Nr 2 x Nr 13 x Nr 12 x Nr 12 x Nr 1 x Nr PUNCTAJ Autoevaluare Comisie

Da / 2 Da/6 Da/6 Da/5 Da/3 Da/4

12 12 12 7.5 4.5 4 52

12 12 12 7.5 4.5 4 52

CRITERIUL 3: CONTRIBUTIA STIINTIFICA a). Articole / studii publicate in reviste de specialitate de circulatie internationala recunoscute (reviste cotate ISI sau indexate in baze de date internationale specifice domeniului, care fac un proces de selectie a revistelor pe baza unor criterii de performanta) si reviste din tara recunoscute de catre CNCSIS Articole / studii PUNCTAJ ISI CNCSIS Alocat per item Autoevaluare Comisie Da/Nr Nu Da/Nr Nu ISI CNCSIS Da/26 Da/6 14 x Nr 1 x Nr NR. TOTAL DE PUNCTE 3 x 26 = 78 1x6=6 84 84 b) Carti si capitole in carti de specialitate CARTI Autor (1) Coautor (2) Coordonator (3) Da/Nr Nu Da/Nr Nu Da/Nr Nu Da/2 Da/19 Da/1 NR. TOTAL DE PUNCTE

Alocat per item (1) (2) (3) 110 x Nr 14 112 x Nr x Nr

PUNCTAJ Autoevaluare (1) (2) 18 57 85

(3) 10

(1) 18

Comisie (2) 57 85

(3) 10

c) Studii publicate in volumele unor manifestari stiintifice nationale / internationale recunoscute (cu ISSN sau ISBN) STUDII PUBLICATE PUNCTAJ ISSN ISBN Alocat per item Autoevaluare Da/Nr Nu Da/Nr Nu Da/47 13 x Nr Nr. total de puncte 141 d) Brevete de inventie: NU ESTE CAZUL

Comisie 141

4 CRITERIUL 2

ACTIVITATEA DE CERCETARE
A. PROIECTE DE CERCETARE-DEZVOLTARE-INOVARE OBTINUTE PRIN COMPETITIE PE BAZA DE CONTRACT/GRANT

TITLU (ACRONIM)

Perioada

Functie cercetator Director d de proiect

1. Proiect CNCSIS 184/2001 2001-2003 Aplicatii ale reologiei fluidelor in biologie si medicina 2004-2006 2. Proiect VIASAN 324/2004 Rolul evidentei computerizate a pacientilor in identificar potentialilor candidati pentru transplantul hepatic si urmarirea dinamicii listei de asteptare (HEPASIST) 3. Proiect VIASAN 322/2004 2004-2006 Rolul manometriei esofagiene in diagnosticul achalasiei pacientii cu disfagie si in evaluarea eficientei tratamentul endoscopic sau chirurgical al afectiunii (ROMAC) 2004-2006 4. Proiect VIASAN 428/2004 Evidenta computerizata prospectiva a pacientilor cu ri pentru dezvoltarea cancerului colorectal la care se impun screeningul si supravegherea (COLOCANS) 2006-2008 5. Proiect CEEX 142/2006 Diagnosticul non-invaziv si markeri de prognostic hepatocarcinomului detectat in leziunile focale nodula din ciroza hepatica (PROSONOHEP) 2006-2008 6. Proiect CEEX 89/2006 Implicaii diagnostice i prognostice ale aspectul endomicroscopic al microvascularizaiei leziunil premaligne i maligne ale tubului digestiv superi (DIAPROGENDO) 2006-2008 7. Proiect CEEX 65/2006 Potentialul terapeutic al celulelor stem hematopoetice afectiunile hepatice (LIVER STEM) cu partener exter Faculty of Medicine, Imperial College Londo Hammersmith Campus, London 2006-2008 8. Proiect CEEX 60/2006 Evaluarea fenotipica si genotipica a pacientilor cu bo inflamatorii intestinale cronice din Romania si generar unui registru biregional computerizat de urmari prospectiva (IBDPROSPECT)

executant

executant

Director d de proiect Cercetator echipa coordonato ului (I Fundeni) Cercetator

Cercetator echipa coordonato ului (UM Carol Davila)

5 CRITERIUL 2

ACTIVITATEA DE CERCETARE
B. STUDII MULTICENTRICE NATIONALE / INTERNATIONALE B. 1. NATIONALE 1. 2. Evaluarea ratei de aderenta la pacientii 2004 - 2006 primesc terapie combinata cu PegIntron Pen Rebetol pentru tratamentul hepatitei C Studiu noninterventional desch 2005 2006 necomparativ cu un singur brat, nationa multicentric, de evaluare a raspunsului tratamentul standard cu PegInterferon alfa 2 si Ribavirina in functie de genotipul virusul hepatitic C si de evaluare epidemiologica genotipurilor virusului hepatitei C la pacien din Romania care au inceput tratament standard cu PegInterferon alfa 2a Ribavirina dupa 1 septembrie 2005 Efficacy and safety of Peginterferon alfa 22005 in derulare (40kD) (Pegasys) in patients with HBe A positive chronic hepatitis B (Protoc ML18089) An open label uncontrolled study to assess th2005-in derulare response of PegIntron in nave patients chronic hepatitis B and D coinfection (V P04603) Open label multicenter trial evaluatin2005 in derulare efficacy and safety of Peginterferon alfa 2 (Pegasys) in patients with chronic hepatitis (CHD) (Protocol ML18788) Epidemiologia infectiilor virale B, D si C 2006-in derulare Romania Standard protocol to assess the diagnost 2006-in derulare value of Fibrotest - Actitest Principal investigator Coinvestigator

3.

Coinvestigator Principal investigator Coinvestigator Principal investigator Coinvestigator

4.

5.

6. 7.

B.2. INTERNATIONALE Studiu 1. Perioada Functie Co-investigator Healing of patients suffering fro 2004 gastroesophageal reflux esophagitis grade Caccording to Los Angeles classification aft treatment with pantoprazole-magnesiu dehydrate 80 mg o.d. in comparison pantoprazole-sodium sesquihydrate 40 mg o. over 4 or 8 weeks (BY 1023/M3-904) PROGRESS Study: Randomized, Multicente 2006 Double-Blind, Phase IV Study Evaluating th derulare Efficacy and Safety of 360 microg Induction Dosin

2.

investigator

6 of Pegasys in Combination with Higher Copeg Doses in Treatment-nave Patients with Chron Hepatitis C Genotype I Virus Infection of Hig Viral Titer and Baseline Body Weight Greater tha or Equal to 85 kg (NV18210) 3. Chemoprevention of colorectal adenom 2006 (International, Multi-centre, randomised, parall derulare group, prospective, double blind, placeb controlled clinical trial evaluating the efficacy an safety of a combination treatment administere over 3 years in patients at risk of experiencing r occurrence of colorectal adenomas) (COLO CP-01) 3. SR121463B in cirrhotic ascites treatment wi 2004 normonatremia: placebo-controlled, dos comparison study (NORMO-CAT) 4. SR121463B in cirrhotic ascites treatment wi 2004 hyponatremia: placebo-controlled, dos comparison study (HYPO-CAT) (LTS5634) 2004 5. SR121463B in cirrhotic ascites with hyponatremi 2004 - 2006 a single-blind, placebo-controlled, long-ter treatment study (EXPO-CAT) (LTS5634) 6. Satavaptan in the prevention of ascites recurrenc 2006 a double-blind, randomized, parallel-grou derulare comparison of satavaptan at 5 to 10 mg daily placebo in the absence of diuretics in patients wi recurrent ascites due to cirrhosis of the liv (SPARe-2) (EFC 6682) 7. A phase 3, multi-center, randomised, double-blin 2005 - 2006 placebo-controlled, parallel-arm study of th efficacy and safety of OPC 6535 tablets in th treatment of subjects with active ulcerative colit (197-02-218) 8. A phase 3, multicenter, randomized, double-blin 2005 - 2006 parallel arm, 52-week dose comparison Study of th Efficacy and Safety of 25 mg QD and 50 mg QD OPC-6535 Oral Tablets and 800 mg BID of Asac in the maintenance of Remission in Subjects wi Ulcerative Colitis (197-02-220) 9. A multicenter, randomized, double-blind, placeb 2006 controlled, parallel group trial to evaluate the safe derulare and efficacy of a new tablet formulation and dosin regimen balsalazide active ulcerative colitis (BZU 3004) 2006 Principal investigator 10. A multicenter, open-label trial to evaluate the lon 2006 term safety and tolerability of a new balsalazidderulare disodium tablet formulation in patients wi ulcerative colitis (BZUC 3005) 2006 (Princip investigator)

Co-investigator

Principal investigator Principal investigator Principal investigator Principal investigator

Co-investigator

Co-investigator

Principal investigator

Principal investigator

7 CRITERIUL 3

CONTRIBUTIA STIINTIFICA
I. LUCRARI ORIGINALE PUBLICATE IN EXTENSO IN REVISTE INDEXATE ISI SI MEDLINE 1. C. Gheorghe, I. Sporea, G. Becheanu, L. Gheorghe. Endoscopic mucosal resection for early gastric cancer. Rom J Gastroenterol 2002; 11: 33-38 2. M. Diculescu, C. Atanasiu, T. Arbanas, A. Croitoru, A. Mihalcea, G. Becheanu, S. Costinean, L. Gheorghe, R. Capsa. Chemoembolization in the treatment of metastatic ileocolic carcinoid. Rom J Gastroenterol 2002; 11: 141-148 3. L. Gheorghe, I. Bancil, C. Gheorghe, V. Herlea, C. Vasilescu, G. Aposteanu. Antroduodenal tuberculosis causing gastric outlet obstruction a rare presentation of a protean disease. Rom J Gastroenterol 2002; 11: 149-152 4. L. Gheorghe, C. Gheorghe, M. Badea, R. Vadan, I. Parvulescu, C. Toader, L. Tugui, O. Papuc, R. Ionescu, C. Preda, I. Calin, M. Diculescu. Infliximab for Crohns disease in clinical practice: the experience of a single center in Romania. Rom J Gastroenterol 2003; 12: 7-13 5. C. Gheorghe, L. Gheorghe, R. Iacob, S. Iacob, I. Simionov, I. Bancil. Argon plama coagulation for radiation proctitis. Rom J Gastroenterol 2003; 12: 107-112 6. R. Vadan, L. Gheorghe, G. Becheanu, R. Iacob, S. Iacob, C. Gheorghe. Predictive factors for the severity of liver fibrosis in patients with chronic hepatitis C and moderate alcohol consumption. Rom J Gastroenterol 2003; 12: 183-188 7. I. Popescu, M. Simionescu, D. Tulbure, A. Sima, C. Catana, L. Niculescu, N. Hancu, L. Gheorghe, M. Mihaila, S. Ciurea, V. Vidu. Homozygous familial hypercholesterolemia: specific indication for domino liver transplantation. Transplantation 2003; 76: 1345-1350 8. M. Jinga, C. Gheorghe, M. Dumitrescu, L. Gheorghe, T. Nicolaie. Endoscopic ultrasound-guided fine needle aspiration biopsy in the diagnosis of pancreatic masses. Rom J Gastroenterol 2004; 13: 49-54 9. L. Gheorghe, S. Iacob, N. Bolog, A. Stoicescu, I. Parvulescu, I. Popescu. Overlap syndrome between autoimmune hepatitis and primary biliary cirrhosis complicated by hepatocellular carcinoma. Case report. Rom J Gastroenterol 2004; 13: 33-38 10. L. Gheorghe, S. Iacob, C. Gheorghe, R. Iacob, I. Simionov, R. Vadan, G. Becheanu, I. Parvulescu, C. Toader. Frequency and predictive factors for overlap syndrome between autoimmune hepatitis and cholestatic liver disease. Eur J Gastroenterol Hepatol 2004; 16: 585-592 11. C. Gheorghe, I. Bancila, R. Stoia, L. Gheorghe, G. Becheanu, C. Dobre, R. Brescan. Regression of gastric MALT-lymphoma under specific therapy may be predicted by endoscopic ultrasound. Rom J Gastroenterol 2004; 13: 129-134 12. L. Gheorghe, I. Popescu, S. Iacob, C. Gheorghe, R. Vadan, A. Constantinescu, R. Iacob, G. Becheanu, C. Angelescu, M. Diculescu. Wilsons disease: a challenge of

8 diagnosis. The 5-years experience of a tertiary centre. Rom J Gastroenterol 2004; 13: 179-185 13. C. Gheorghe, O. Pascu, L. Gheorghe, R. Iacob, E. Dumitru, M. Tantau, R, Vadan, A. Goldis, G. Balan, S. Iacob, D. Dobru, A. Saftoiu. Epidemiology of inflammatory bowel disease in adults who refer to gastroenterology care in Romania: a multicentric study. Eur J Gastroenterol Hepatol 2004; 16: 1153-1161 14. L. Gheorghe, S. Iacob, I. Popescu. Living donor liver transplantation and hepatitis C. Rom J Gastroenterol 2004; 13: 317-327 15. Balan C, Baluta C, Gheorghe L, Gheorghe C, Gheorghiu E, Ursu G. Experimental determination of blood permittivity and conductivity in simple shear flow. Clin Hemorheol Microcirc 2004; 30 (3-4): 359-364 16. Popescu I, Ionescu M, Tulbure D, Ciurea S, Baila S, Brasoveanu V, Hrehoret D, Sarbu-Boeti P, Pietrareanu D, Alexandrescu S, Dorobantu B, Gheorghe L, Gheorghe C, Mihaila M, Boros M, Croitoru M, Herlea V. Transplantul hepatic ortotopic de la donator cadavru la adult. Experienta Centrului de Chirurgie Generala si Transplant Hepatic Fundeni. Chirurgia 2005; 100: 13-26 17. L. Gheorghe, I. Popescu, R. Iacob, S. Iacob, C. Gheorghe. Predictors of death on the waiting list for liver transplantation characterized by a long waiting time. Transplant International 2005; 18: 572-576 18. L. Gheorghe, S. Iacob, C. Gheorghe. Liver biopsy under ultrasound control for diffuse liver disease toward a faster, safer, cost-effective and easy acceptable procedure (Letter). Rom J Gastroenterol 2005; 14: 97-98 19. R. Vadan, L. Gheorghe. Progression of liver fibrosis in young blood donors infected with hepatitis C virus: different predictive factors? (Letter). Rom J Gastroenterol 2005; 14: 99-100 20. L. Gheorghe, M. Grigorescu, S. Iacob, D. Damian, C. Gheorghe, R. Iacob, I. Simionov, R. Vadan, I. Parvulescu, I. Bancila. Effectiveness and tolerability of pegylated interferon -2a and ribavirin combination therapy in Romanian patients with chronic hepatitis C: from clinical trials to clinical practice. Rom J Gastroenterol 2005; 14: 109115 21. Liana Gheorghe, Razvan Iacob, Roxana Vadan, Speranta Iacob, Cristian Gheorghe. Improvement of hepatic encephalopathy using a modified high-calorie high-protein diet. Rom J Gastroenterol 2005; 14: 231-238 22. Liana Gheorghe, Speranta Iacob, Iulia Simionov, Roxana Vadan, Cristian Gheorghe, Razvan Iacob, Iulia Parvulescu, Ileana Constantinescu. Natural history of compensated hepatitis B and D viruses cirrhosis. Rom J Gastroenterol 2005; 14: 329-336 23. Razvan Iacob, Speranta Iacob, Liana Gheorghe, Cristian Gheorghe, Mircea Diculescu. The use of IT in the medical system has economic and research advantages the experience of Fundeni Gastroenterology and Hepatology Center. Rom J Gastroenterol 2005; 14: 426-429 24. Popescu I, Ionescu M, Ciurea S, Brasoveanu V, Sarbu-Boeti P, Hrehoret D, Tomulescu V, Alexandrescu S, Dorobantu B, Grigorie R, Jemna C, Gheorghe L, Anghel

9 R, Croitoru A, Herlea V, Boros M. Tratamentul multimodal al carcinomului hepatocelular. Analiza unei experiente clinice de 123 cazuri in 5 ani. Chirurgia 2005; 100; 321-331 25. Cristian Gheorghe, Liana Gheorghe, Speranta Iacob, Razvan Iacob, Irinel Popescu. Primary prophylaxis of variceal bleeding in cirrhotics awaiting liver transplantation. Hepato-Gastroenterology 2006; 53: 552-557 26. Cristian Gheorghe, Codrut Stanescu, Liana Gheorghe, Ion Bancila, Vlad Herlea, Gabriel Becheanu, Daniela Voinea, Ioana Lupescu, Rodica Anghel, Adina Croitoru, and Irinel Popescu. The preoperative noninvasive EUS evaluation in patients with esophageal cancer considered for esophagectomy. Journal of Gastrointestinal and Liver Diseases 2006; 15: 131-137

Formatted: Font color: Auto, English (U.K.)

II.

LUCRARI

ORIGINALE

PUBLICATE

IN

EXTENSO

IN

REVISTE

RECUNOSCUTE CNCSIS 1. L. Gheorghe. Tratamentul hepatitei recurente posttransplant. Annals of Fundeni Hospital 2002; 7: 25-30 2. R. Iacob, L. Gheorghe, S. Iacob, V. Herlea, G. Becheanu, D. Hrehoret, I. Popescu. Dysplasia-associated lesion or mass (DALM) during the neoplastic sequence inflammation-dysplasia-carcinoma: diagnosis and management. Report of three cases. Annals of Fundeni Hospital 2003; 8: 13-21 3. Mihaela Badea, Roxana Vadan, G. Becheanu, V. Herlea, Liana Gheorghe. The natural history of an inflammatory bowel disease with particular complications. Annals of Fundeni Hospital 2004; 9: 33-38 4. Roxana Vadan, Liana Gheorghe. Biologic therapies: the new era in inflammatory bowel disease\treatment. Annals of Fundeni Hospital 2004; 9: 44-54 5. C. Gheorghe, L. Gheorghe, I. Popescu. The role of endoscopic ultrasound (EUS) for re-staging of esophageal squamos carcinoma after chemoradiotherapy. Archives of the Balkan Medical Union 2005; 40: 61-62 6. C. Gheorghe, A. Constantinescu, L. Gheorghe, V. Herlea, G. Becheanu, D. Pietrareanu. Gastric neuroendocrine tumor in a child: endoscopic and echoendoscopic features. Archives of the Balkan Medical Union 2005; 40: 123-125 CRITERIUL 3

CONTRIBUTIA STIINTIFICA
III. CARTI SI CAPITOLE DE CARTE III. A. CARTI 1. Vademecuum n Gastroenterologie - Afeciuni ale tubului digestiv (partea I) L. S. Gheorghe, C. Gheorghe, Editura Nemira, Bucureti 2002 2. Cancerele digestive: diagnostic, supraveghere si tratament indrumar practic.

10 C. Gheorghe, L. Gheorghe. Editura Celsius-All, Bucuresti 2005 3. Actualitati in hepatita C 2006. Sub redactia Liana Gheorghe, Cristian Gheorghe. Editura Celsius, Bucuresti 2006 III. B. CAPITOLE DE CARTE 1. Bolile inflamatorii intestinale idiopatice L. Gheorghe, C. Gheorghe. n: T. Ciurea, O. Pascu, C. Stanciu, eds. Actualiti n Gastroenterologie i Hepatologie 2003. Bucureti: Editura Medical 2003: 201-234 2. Ciroza biliar primitiv L. Gheorghe. n: T. Ciurea, O. Pascu, C. Stanciu, eds. Actualiti n Gastroenterologie i Hepatologie 2003. Bucureti: Editura Medical 2003: 759-775 3. Tratamentul antiviral al hepatitei recurente post-transplant L. Gheorghe. n: T. Ciurea, O. Pascu, C. Stanciu, eds. Actualiti n Gastroenterologie i Hepatologie 2003. Bucureti: Editura Medical 2003: 825-841 4. Tratamentul medical al pancreatitei cronice L. Gheorghe. n: T. Ciurea, O. Pascu, C. Stanciu, eds. Actualiti n Gastroenterologie i Hepatologie 2003. Bucureti: Editura Medical 2003: 867-873 5. Principii de terapie nutriional n gastroenterologie i hepatologie L. Gheorghe, C. Gheorghe. n: T. Ciurea, O. Pascu, C. Stanciu, eds. Actualiti n Gastroenterologie i Hepatologie 2003. Bucureti: Editura Medical 2003: 943-967 6. C. Gheorghe, L. Gheorghe. Hipertensiunea portala. In: I. Popescu, ed. Chirurgia ficatului. Bucuresti: Editura Universitara Carol Davila 2004: 743-764 7. L. Gheorghe, C. Gheorghe. Teste functionale hepatice. In: I. Popescu, ed. Chirurgia ficatului. Bucuresti: Editura Universitara Carol Davila 2004: 175-184 8. C. Gheorghe, L. Gheorghe. Ascita si peritonita bacteriana spontana. In: I. Popescu, ed. Chirurgia ficatului. Bucuresti: Editura Carol Davila 2004: 841-852 9. L. Gheorghe, C. Gheorghe. Punctia bioptica hepatica. In: I. Popescu, ed. Chirurgia ficatului. Bucuresti: Editura Universitara Carol Davila 2004: 185-198 10. C. Gheorghe, L. Gheorghe. Ciroza hepatica. In: I. Popescu, ed. Chirurgia ficatului. Bucuresti: Editura Universitara Carol Davila 2004: 829-840 12. L. Gheorghe, C. Gheorghe. Encefalopatia hepatica. In: I. Popescu, ed. Chirurgia ficatului. Bucuresti: Editura Universitara Carol Davila 2004: 853-862 13. L. Gheorghe, C. Gheorghe. Sindromul hepato-renal. In: I. Popescu, ed. Chirurgia ficatului. Bucuresti: Editura Universitara Carol Davila 2004: 863-872 14. T. Marinescu, L. Gheorghe. Boala Wilson. In: I. Popescu, ed. Chirurgia ficatului. Bucuresti: Editura Universitara Carol Davila 2004: 897-906 15. L. Gheorghe, C. Gheorghe. Hepatitele autoimune. n: M. Grigorescu, ed. Tratat de Gastroenterologie i Hepatologie (volumul II). Bucureti, Ed. Medicala Naional 2004 : 539-553

11 16. L. Gheorghe, C. Gheorghe. Sindromul de overlap autoimun. n: M. Grigorescu, ed. Tratat de Gastroenterologie i Hepatologie (volumul II). Bucureti, Ed. Medicala Naional 2004: 554-561 17. Ion Bancila, Radu Tutuian, Elena Savulescu, Cristian Gheorghe, Liana Gheorghe, Donald O. Castell. Differences in baseline esophageal intraluminal impedance between achalasia patients and patients with normal esophageal peristalsis A case-control study. In: D.L. Dumitrascu, L. Nedelcu, eds. Neurogastroenterology from basic knowledge to clinical practice. Editura Medicala Universitara Iuliu Hatieganu, Cluj Napoca 2005: 8892 18. L. Gheorghe. Boli inflamatorii intestinale: de la imunopatogenez la tratament. In: Doru Dejica, ed. Tratat de imunoterapie. Editura Mega, Cluj Napoca 2006: 682-705 19. L. Gheorghe. Standardul actual de tratament in hepatita cronica C este acesta susceptibil la optimizare? In: M. Grigorescu, C. Stanciu, eds. Actualitati in diagnosticul si tratamentul hepatitelor cornice virale. Editura Teognost, Cluj Napoca 2006: 36-43 CRITERIUL 3

CONTRIBUTIA STIINTIFICA
IV. STUDII PUBLICATE IN REZUMAT IN VOLUMELE UNOR MANIFESTARI INTERNATIONALE RECUNOSCUTE (ISSN, ISBN) 1. C. Gheorghe, L. Gheorghe, R. Vadan, D. Hrehoret, I. Popescu. Prophylactic banding ligation of high risk esophageal varices in patients on the waiting list for liver transplantation: An interim report. J Hepatol 2002; 36 (Suppl 1): 38 (114) 2. I. Simionov, L. Gheorghe, C. Gheorghe, R. Vadan. Compliance of cirrhotic patients with spontaneous bacterial peritonitis to prophylactic antibiotic therapy: influence on the recurrence. J Hepatol 2002; 36 (Suppl 1): 55 (177) 3. R. Vadan, C. Croitoru, L. Gheorghe, A. Frujinoiu, C. Mihil, C. Constantin, I. Iova, I. Bncil. Liver steatosis in chronic hepatitis C: a factor of severity ? J Hepatol 2002; 36 (Suppl 1): 249 (897) 4. L. Gheorghe, C. Gheorghe, R. Vadan, C. Croitoru, C. Mihaila, I. Bancila, I. Iova. Effect of high-calorie, high-protein diet in cirrhotic patients with hepatic encephalopathy. J Hepatol 2002; 36 (Suppl 1): 171 (605) 5. C. Gheorghe, L. Gheorghe, G. Becheanu, A. Frujinoiu, C. Mihaila. Diminutive colonic adenomas and the risk for colorectal cancer. Gut 2002; 51 (Suppl 3): A261 6. R. Vadan, C. Gheorghe, I. Iova, C. Mihaila, A. Frujinoiu, C. Croitoru, L. Gheorghe. Predictive factors of rebleeding in patients with endoscopic variceal ligation. Gut 2002; 51 (Suppl 3): A184 7. C. Gheorghe, L. Gheorghe, G. Becheanu, A. Frujinoiu, C. Mihaila. Diminutive colonic adenomas and the risk for colorectal cancer. Gut 2002; 51 (Suppl 3): A261

12 8. R. Vadan, C. Gheorghe, I. Iova, C. Mihaila, A. Frujinoiu, C. Croitoru, L. Gheorghe. Predictive factors of rebleeding in patients with endoscopic variceal ligation. Gut 2002; 51 (Suppl 3): A184 9. L. Gheorghe, C. Gheorghe, R. Vadan, C. Toader, I. Simionov. Efficacy of simultaneously administration of terlipressine and human albumin versus terlipressine and plasma expanders for the reversion of type I hepato-renal syndrome in patients on the waiting list for liver transplantation. Gut 2002; 51 (Suppl 3): A68 10. L. Gheorghe, C. Gheorghe, R. Vadan, I. Parvulescu. Overlap of autoimmune hepatitis and primary cholestatic liver disease: frequency and predictive factors Gut 2002; 51 (Suppl III): A38 11. L. Gheorghe, C. Gheorghe, M. Badea, R. Vadan, I. Parvulescu, C. Toader, L. Tugui, I. Popescu. Infliximab for refractory and fistulizing Crohns disease: saving patients from surgical treatment. Hepato-Gastroenterology 2002; 49 (Suppl 2): CXII-CXIII (P033) 12. C. Gheorghe, G. Becheanu, I. Parvulescu, L. Gheorghe. Minimal histopathological changes in non-erosive gastroesophageal reflux disease. Hepato-Gastroenterology 2002; 49 (Suppl 2): CCXXVI (P306) 13. I. Parvulescu, C. Gheorghe, G. Becheanu, L. Gheorghe. Efficacy of the treatment with Famotidine in non-erosive gastroesophageal reflux disease. HepatoGastroenterology 2002; 49 (Suppl 2): CCXXVI-CCXXXVII (P307) 14. I. Simionov, L. Gheorghe, G. Becheanu, I. Constantinescu. The role of HBV coinfection on severity of liver disease and the response to treatment compared with HCV infection only. J Hepatol 2003; 38 (Suppl 2): 174 15. C. Balan, C. Balut, L. Gheorghe, C. Gheorghe, E. Gheorghiu, G. Al. Ursu. Rheological and electrical properties of blood in simple shear flow experimental investigations and theoretical modeling. Abstract Book of 12nd European Conference on Clinical Hemorheology, 2003: S9.4 16. L. Gheorghe, S. Iacob, R. Iacob, C. Gheorghe, A. Stoicescu, I. Popescu. Predictors of death on the waiting list for liver transplantation in Romania. Gut 2003; 52 (Suppl 6): A160 (TUE-G-213) 17. C. Gheorghe, R. Iacob, L. Gheorghe, S. Iacob, I. Simionov, I. Bancila. Argon-plasma coagulation in the treatment of radiation proctitis what power setting to choose? Gut 2003; 52 (Suppl 6): A188 (WED-G-050) 18. R. Vadan, L. Gheorghe, G. Becheanu, R. Iacob, M. Dumbrava, C. Gheorghe. The influence of moderate alcohol intake on the severity of chronic hepatitis C. Gut 2003; 52 (Suppl 6): A104 (MON-G-226) 19. R. Iacob, S. Iacob, L. Gheorghe, M. Diculescu, C. Gheorghe, I. Constantinescu, A. Ionescu, M. Ciocarlan. The side effect profile and tolerability of Peginterferon alpha 2a in combination with RBV compared with conventional interferon alpha 2a and
Formatted: Spanish (Spain-Modern Sort)

13 RBV in patients with chronic hepatitis C. Gut 2003; 52 (Suppl 6): A104 (MON-G227) 20. S. Iacob, R. Iacob, M. Diculescu, L. Gheorghe, I. Simionov, R. Vadan, I. Stanel. A rapid diagnostic test for HBV infection: efficacy and advantages. HepatoGastroenterology 2003; 50 (Suppl I): CLII (P75) 21. I. Parvulescu, S. Iacob, R. Iacob, L. Gheorghe. MELD, Child-Pugh and Maddrey scores in assessing the prognosis of patients with alcoholic hepatitis superimposed on alcoholic cirrhosis. Hepato-Gastroenterology 2003; 50 (Suppl I): CXXVI (P127) 22. S. Iacob, L. Gheorghe, R. Iacob, C. Gheorghe, A. Stoicescu, I. Popescu. An alternative model to predict survival for patients on the waiting list for liver transplantation useful in the case of long waiting period. Hepato-Gastroenterology 2003; 50 (Suppl I): CXXIX (P7136) 23. C. Gheorghe, R. Iacob, I. Bancila, N. Zamfirescu, L. Gheorghe, S. Iacob, R. Brescan, C. Popescu, C. Zaharia. Efficacy and complications of endoscopic dilation in achalasia. Hepato-Gastroenterology 2003; 50 (Suppl I): CXXXIV (P41) 24. R. Iacob, C. Gheorghe, M. Diculescu, S. Iacob, L. Gheorghe. Pros and cons of band ligation versus sclerotherapy in the treatment of variceal bleeding. HepatoGastroenterology 2003; 50 (Suppl I): CXXXV (P43) 25. I. Simionov, L. Gheorghe, A. Constantinescu, R. Iacob. Prevalence and significance of steatosis in subjects with normal hepatic function tests. J Hepatol 2004; 40 (Suppl 1): 176 (601) 26. R. Vadan, L. Gheorghe, M. Badea, S. Iacob, C. Gheorghe. The prevalence and risk factors for malnutrition in patients with cirrhosis. Clinical Nutrition 2004; 23: 872 (04-A-622-ESPEN) 27. L. Gheorghe, S. Iacob, C. Gheorghe, R. Vadan, R. Iacob, A. Constantinescu, C. Angelescu, I. Popescu. Diagnosis of Wilsons disease: still a challenge. Gut 2004; 53 (Suppl VI): A 91 28. R. Iacob, G. Becheanu, M. Dumbrava, S. Iacob, L. Gheorghe, C. Gheorghe. Concordance between three histologic scoring systems used for the evaluation of chronic hepatitis C. Gut 2004; 53 (Suppl VI): A 173 29. L. Tugui, L. Gheorghe, C. Gheorghe, G. Becheanu, R. Vadan, I. Simionov, A. Dumitru, R. Iacob, M. Diculescu. Hepatic involvement in celiac disease: prevalence, etiopathogenesis, and risk factors. Gut 2004; 53 (Suppl VI): A 199 30. C. Gheorghe, R. Iacob, I. Bancila, G. Becheanu, L. Gheorghe, S. Iacob. Small colorectal advanced adenomas: what incidence and associated risk factors ? Gut 2004; 53 (Suppl VI): A 268 31. M. Ciocarlan, M.E. Ciocarlan, L.S. Gheorghe, C. Angelescu, I. Simionov, C. Preda, A. Croitoru, M. Diculescu. How can we predict associated portal vein thrombosis

14 when hepatocellular carcinoma is diagnosed in liver cirrhosis ? Gut 2004; 53 (Suppl VI): A 254 32. C. Gheorghe, R. Iacob, L. Gheorghe, S. Iacob, R. Vadan, M. Diculescu, A. Goldis, E. Dumitru, D. Dobru, E. Miutescu, A. Saftoiu, A. Fraticiu, O. Pascu. Prevalence of malnutrition and risk factors in patients with liver diseases referred to tertiary gastroenterology assistance: a multicentric study. J Gastroenterol Hepatol 2004; 19 (Suppl): A799 33. L. Gheorghe, S. Iacob, R. Iacob, C. Gheorghe. Natural history of compensated hepatitis B and D virus - related cirrhosis. J Gastroenterol Hepatol 2004; 19 (Suppl): A806 34. S. Iacob, L. Gheorghe, A. Istrate, R. Crintea, R. Iacob, C. Gheorghe. Predictive factors of non-neoplastic portal vein thrombosis in cirrhotic patients. J Hepatol 2005; 42 (Suppl 2): 81 35. C. Gheorghe, S. Iacob, I. Bancila, L. Gheorghe, R. Iacob, M. Fleancu, C. Marica. Changing epidemiologic pattern of gastric pattern in Romania. HepatoGastroenterology 2005; 52 (Suppl 1): A86 36. C. Gheorghe, S. Iacob, L. Gheorghe, R. Iacob, I. Popescu. Risk factors for colorectal polyps in cirrhostic patients included on the waiting list for liver transplantation. Hepato-Gastroenterology 2005; 52 (Suppl 1): A135 37. C. Gheorghe, L. Gheorghe, S. Iacob, R. Iacob. Malnutrition as a risk factor for bleeding after endoscopic band ligation in patients with liver cirrhosis. Clinical Nutrition 2005; 24: 619 (P168) 38. C. Gheorghe, S. Iacob, L. Gheorghe, R. Iacob. Is cirrhosis a risk factor for colorectal polyps? Prospective study in patients included on the waiting list for liver transplantation. Gut 2005; 54 (Suppl VII): A194 39. R. Iacob, J. Quinton, F. Guillemot, F. Pattou, I. Bancila, C. Gheorghe, S. Iacob, L. Gheorghe, M. Diculescu. Esophageal manometry abnormalities after gastric banding for morbid obesity. Gut 2005; 54 (Suppl VII): A14 40. S. Iacob, L. Gheorghe, C. Gheorghe, R. Iacob, D. Bucur, A. Croitoru. Predictors of hepatocellular carcinoma occurrence in patients with cirrhosis. Hepatology 2005; 42 (Suppl 1): 396A 41. S. Iacob, S. Beckebaum, R. Iacob, V. Cicinnati, C. Klein, L. Gheorghe, C. Gheorghe, I. Popescu, A. Frilling, M. Malago, G. Gerken, C. Broelsch. A model to predict one year graft failure in patients transplanted for HCV cirrhosis. Journal of Hepatology 2006; 44 (Suppl 2): S62 (Abstract#144) 42. S. Iacob, S. Beckebaum, V. Cicinnati, R. Iacob, L. Gheorghe, C. Gheorghe, I. Popescu, A. Frilling, M. Malago, G. Gerken, C. Broelsch. Predictive factors of sustained virological and histological response after combined antiviral therapy in

15 transplanted patients with recurrent hepatitis C. Journal of Hepatology 2006; 44 (Suppl 2): S215 (Abstract#580) 43. S. Iacob, S. Beckebaum, V. Cicinnati, R. Iacob, C. Klein, L. Gheorghe, C. Gheorghe, I. Popescu, A. Frilling, M. Malago, G. Gerken, C. Broelsch. Protective factors for severe recurrence of hepatitis C after liver transplantation. Gastroenterology 2006; 130 (Suppl 2): A-79 (Abstract 541) 44. S. Iacob, S. Beckebaum, R. Iacob, V. Cicinnati, C. Klein, L. Gheorghe, C. Gheorghe, I. Popescu, A. Frilling, M. Malago, G. Gerken, C. Broelsch. Predictive factors for graft and patient survival following liver transplantation for hepatitis C. Gastroenterology 2006; 130 (Suppl 2): A-500: (Abstract T1221) 45. C. Gheorghe, I. Parvulescu, L. Gheorghe, R. Iacob, I. Bancila. Frequency and predictive factors for acute biliary pancreatitis in patients with choledocolithiasis. Hepato-Gastroenterology 2006; 53 (Suppl I): 192 46. M. Jinga, C. Gheorghe, T. Nicolae, L. S. Gheorghe, F. Vasilescu, P. Nuta, R. Costache, D. G. Popescu, L. F. Florea, R. Brescan, E. Michiu, T. Tabaran. The role of endoscopic ultrasonography in diagnosis and management of the subepithelial lesions in the upper gastrointestinal tract. Endoscopy 2006; 38: P13 47. Iacob R, Bancila I, Gheorghe C, Bucur D, Voinea D, Iacob S, Gheorghe L, Croitoru A, Ciurea S, Pitigoi D, Manuc M, Diculescu M, Popescu I. The prospective evaluation of resources needed for colonoscopic surveillance of patients with curative resection for colorectal cancer in a Romanian gastroenterology referral center Data of COLOCANS Registry. Gut 2006; 55 (Suppl 5): 188 CRITERIUL 3

CONTRIBUTIA STIINTIFICA
V. PREZENTARI ORALE IN CADRUL UNOR MANIFESTARI NATIONALE SI INTERNATIONALE V. A. MANIFESTARI INTERNATIONALE 1. L. Gheorghe, C. Gheorghe, R. Vadan, C. Croitoru, C. Mihaila, I. Bancila, I. Iova. High calorie high protein diet in cirrhotic patients with hepatic encephalopathy Presidential Session (General Session I) Biennial Meeting of the International Association for the Study of the Liver (IASL) and 37-th Annual Meeting of the European Association for the Study of the Liver (EASL), Madrid, 15 aprilie 2002 2. L. Gheorghe, C. Gheorghe, R. Vadan, C. Toader, I. Simionov. Efficacy of simultaneously administration of terlipressine and human albumin versus terlipressine and plasma expanders for the reversion of type I hepato-renal syndrome in patients on the waiting list for liver transplantation Sesiune: New trends in the management of ascites

16 10th UEGW, Geneva, 23 octombrie 2002 3. L. Gheorghe, C. Gheorghe, R. Vadan, I. Parvulescu. Overlap of autoimmune hepatitis and primary cholestatic liver disease: frequency and predictive factors Session: Cholestatic liver disease 10th UEGW, Geneva, 22 octombrie 2002 4. L. Gheorghe. Antiviral therapy peri-liver transplantation Session: Liver transplantation 5-th Symposium and Postgraduate Course of the International Association of Surgeons and Gastroenterologists (IASG), Bucuresti, 9-11 aprilie 2003 5. S. Iacob, L. Gheorghe, C. Gheorghe, R. Iacob, D. Bucur, A. Croitoru. Predictive factors for the development of hepatocellular carcinoma in cirrhotic patients Al 14-lea Congres International Association of Surgeons and Gastroenterologists, Zurich, 9-12 septembrie 2004 6. Jean Depamphilis, L. Gheorghe, Adebayo Lawal. Management of Hematologic Issues. NV18210 (Randomized, Multicenter, Double-Blind, Phase IV Study Evaluating the Efficacy and Safety of 360 microg Induction Dosing of Pegasys in Combination with Higher Copegus Doses in Treatment-nave Patients with Chronic Hepatitis C Genotype I Virus Infection of High Viral Titer and Baseline Body Weight Greater than or Equal to 85 kg) Investigators Meeting, 18-20 octombrie 2006, St. Julinas, Malta 7. L. Gheorghe. Management of Side Effects during Hepatitis C Antiviral Therapy. 14th International Postgraduate Course of IASGO, 7-9 decembrie 2006, Atena, Grecia

V. B. MANIFESTARI NATIONALE 1. L. Gheorghe. Tratamentul de intretinere in bolile inflamatorii intestinale idiopatice Sesiunea: Tratamentul bolilor inflamatorii intestinale idiopatice Simpozionul National de Gastroenterologie si Endoscopie Digestiva, Cluj-Napoca, 13-16 iunie 2002 2. L. Gheorghe. Terapia imunosupresoare si cu agenti biologici a bolilor inflamatorii intestinale idiopatice Sesiunea: Tratamentul bolilor inflamatorii intestinale idiopatice Simpozionul National de Gastroenterologie si Endoscopie Digestiva, Cluj-Napoca, 13-16 iunie 2002 3. L. Gheorghe. Bolile hepatice autoimune. Sindromul de overlap Congresul National de Hepatologie, Bucuresti, 27-28 septembrie 2002 4. L. Gheorghe. Nutritia totala parenterala (TPN) in bolile inflamatorii intestinale Al treilea Simpozion National de Nutritie Clinica, Brasov, 8-10 noiembrie 2002

17

5. L. Gheorghe. Infliximab (Remicade) in tratamentul bolii Crohn Conferinta Nationala a Societatii Romane de Alergologie si Imunologie Clinica, Cluj-Napoca, 18-20 iunie 2003 6. L. Gheorghe. Terapia antivirala in hepatita recurenta post-transplant Al 13-lea Congres National de Hepatologie, Bucuresti, 26-27 iunie 2003 7. L. Gheorghe. Sindromul de overlap intre hepatita autoimuna si bolile colestatice hepatice Al 13-lea Congres National de Hepatologie, Bucuresti, 26-27 iunie 2003 8. L. Gheorghe. Tratamentul antiviral al hepatitei recurente post-transplant Sesiunea: Tratamentul hepatitelor cronice virale Al 9-lea Congres Roman de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova, 24-27 septembrie 2003 9. L. Gheorghe. Ciroza biliara primitiva Sesiunea: Ciroza hepatica Al 9-lea Congres Roman de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova, 24-27 septembrie 2003 10. L. Gheorghe. Tratamentul medical al pancreatitei cronice Sesiunea: Pancreatita cronica Al 9-lea Congres Roman de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova, 24-27 septembrie 2003 11. L. Gheorghe. Principiile terapiei nutritionale Simpozion Fresenius-Kabi: Nutritia in gastroenterologie si hepatologie Al 9-lea Congres Roman de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova, 24-27 septembrie 2003 12. L. Gheorghe. Infliximab (Remicade) in tratamentul bolii Crohn Simpozion Schering-Plough: Boala Crohn: prezent si viitor Al 9-lea Congres Roman de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova, 24-27 septembrie 2003 13. L. Gheorghe. Terapia combinata cu Peginterferon alfa-2a si Ribavirina versus Interferon alfa-2a si Ribavirina in hepatita cronica C efecte adverse si tolerabilitate Al 9-lea Congres Roman de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova, 24-27 septembrie 2003 14. L. Gheorghe. Profilul de siguranta si tolerabilitate al noii generatii de interferon pegylat alfa-2a (Pegasys) Simpozion HoffmannLa Roche: Pegasys: Noua generatie de terapie antivirala in managementul hepatitei cronice virale C Al 9-lea Congres Roman de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Craiova, 24-27 septembrie 2003

18 15. L. Gheorghe. Nutritia la pacientul cu encefalopatie hepatica Sesiune: Nutritia in afectiuni hepatice Al 4-lea Simpozion si Curs postuniversitar al Societatii Romane de Nutritie Enterala si Parenterala (ROSPEN), Poiana Brasov, 24-26 octobrie 2003 16. L. Gheorghe. Progrese in transplantul hepatic Masa rotunda : Ciroza hepatica Simpozionul National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Constanta, 1-3 septembrie 2004 17. L. Gheorghe. Progrese in patogeneza colestazei intrahepatice dobandite : ciroza hepatica primitiva si colangita sclerozanta primitiva Masa rotunda : Colestaza intrahepatica de la fiziopatologia moleculara la aplicatii terapeutice Simpozionul National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Constanta, 1-3 septembrie 2004 18. L. Gheorghe. State of the art lecture : Efecte adverse la tratamentul cu interferon pegylat alfa-2a 40kDa si ribavirina pentru hepatita cronica VHC Simpozionul National de Gastroenterologie, Hepatologie si Endoscopie Digestiva, Constanta, 1-3 septembrie 2004 19. L. Gheorghe. Nutriia pacientului cu encefalopatie hepatic Mas rotund: Nutriia la pacientul hepatic 5th ROSPEN, Poiana Brasov, 11-14 noiembrie 2004 20. L. Gheorghe. De la patogeneza la terapie in bolile inflamatorii intestinale Simpozionul CONECT 2005: Performante terapeutice actuale in bolile inflamatorii imun mediate organizat de Academia de Stiinte Medicale, Societatea Romana de Reumatologie si Societatea Romana de Farmacologie Terapeutica si Toxicologie Clinica, Sinaia 25-26 martie 2005 21. L. Gheorghe. Cum influenteaza serologia autoimuna managementul hepatitelor cronice virale si non-virale Al XXVI-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva 9-11 iunie 2005 Timisoara 22. L. Gheorghe. Steatohepatita non-alcoolica : principii terapeutice. Masa rotunda : Steatohepatita non-alcoolica (NASH) : situatia in Romania, profilul factorilor de risc, patogeneza, diagnostic, posibilitati terapeutice Al XXVI-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva 9-11 iunie 2005 Timisoara 23. L. Gheorghe. Hepatita D : etiopatogeneza si istorie naturala Masa rotunda : Hepatita cronica bivirusala B+D Al XXVI-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva 9-11 iunie 2005 Timisoara 24. L. Gheorghe. Tendinte epidemiologice in cancerul hepatocelular in Romania si in lume

19 Masa rotunda : Evolutia cancerelor digestive in ultimii 10 ani in Romania Al XXVI-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva 9-11 iunie 2005 Timisoara 25. L. Gheorghe. Tratamentul standard al bolilor inflamatorii intestinale. Masa rotunda : Bolile inflamatorii intestinale. Al XXVII-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva 14-17 iunie 2006 Poiana Brasov 26. L. Gheorghe. Optiuni terapeutice in afectiunile colestatice hepatice: o abordare fundamentata pe experienta clinica. Al XXVII-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva 14-17 iunie 2006 Poiana Brasov 27. L. Gheorghe. Emerging strategies toward IDEAL therapy in patients with chronic hepatitis C Al XXVII-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva 14-17 iunie 2006 Poiana Brasov 28. L. Gheorghe. Current therapies for recurrent allograft hepatitis C Masa rotunda: Transplantul hepatic si infectia cu VHC. Al XXVII-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva 14-17 iunie 2006 Poiana Brasov 29. L. Gheorghe. Hipertensiunea portala non-cirotica: sindromul Budd Chiari si obstructia extrahepatica a venei porte Masa rotunda : Hipertensiunea portala Al XXVII-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva 14-17 iunie 2006 Poiana Brasov 30. L. Gheorghe. Hipertensiunea porto-pulmonara Masa rotunda : Complicatiile cirozei hepatice Al XXVII-lea Simpozion National de Gastroenterologie, Hepatologie si Endoscopie digestiva 14-17 iunie 2006 Poiana Brasov 31. L. Gheorghe. Tratamentul medicamentos in pancreatita cronica. Al IX-lea Simpozion National Prof. Dr. Dimitrie Gerota, 11-13 octombrie 2006, Brasov 32. L. Gheorghe. Nutritia si ficatul gras nonalcoolic Al VII-lea Simpozion de Nutritie Clinica si Metabolism, 9-12 noiembrie 2006, Poiana Brasov

20 CRITERIUL 3

CONTRIBUTIA STIINTIFICA
VI. PRIORITI NAIONALE N GASTROENTEROLOGIE I HEPATOLOGIE PUBLICATE IN REVISTE INDEXATE MEDLINE SI ISI THOMSON 1. Stabilirea primului Registrul de Polipoz Adenomatoas Familial din Romania in Institutul Clinic Fundeni: cuprinde pacientii cu polipoza adenomatoasa investigati in clinica din 1990 L. Gheorghe, G. Aposteanu, C. Gheorghe, R. Vdan, L. ugui, M. Ionescu, I. Popescu, Al. Oproiu. Clinical and epidemiological features of adenomatous polyposis coli and the risk for colorectal cancer: The Fundeni Polyposis Register. Romanian J Gastroenterol 1999; 8: 97-105 2. Stabilirea primului Registru de Cancer Colorectal Ereditar Non-Polipozic din Romania (1989-1996) L. Gheorghe, G. Aposteanu, C. Gheorghe, Al. Oproiu. Screening for hereditary nonpolyposis colorectal cancer within a County Register in Romania. Gut 1996, 39 (Suppl 3): A132 3. Prima lucrare de epidemiologie a bolii celiace in Romania L. Gheorghe, C, Gheorghe, G, Aposteanu, C. Popescu, C. Toader-Drgulin, Al. Oproiu. Clinical spectrum of adult celiac disease in a referal center for Southern Romania. Associated disorders and short term survival. Romanian J Gastroenterol 1996; 5: 223-228 4. Eficienta si inocuitatea tratamentul biologic cu Infliximab (Remicade) n boala Crohn. Centrul de Gastroenterologie reprezinta un centru national pentru tratamentul cu infliximab, acumuland cea mai mare experienta clinico-terapeutica din Romania (25 pacienti in 2 ani) L. Gheorghe, C. Gheorghe, M. Badea, et al. Infliximab n tratamentul bolii Crohn: 11 cazuri n 12 luni - comunicare la Sesiunea tiinific a Institutului Clinic Fundeni, decembrie 2001 L. Gheorghe, C. Gheorghe, M. Badea, R. Vadan, I. Parvulescu, C. Toader, L. Tugui, O. Papuc, R. Ionescu, C. Preda, I. Calin, M. Diculescu. Infliximab for Crohns disease in clinical practice: the experience of a single center in Romania. Rom J Gastroenterol 2003; 12: 7-13 5. Studiu pilot in Romania efectuat pe 22 de pacienti asupra eficientei si tolerabilitatii terapiei combinate cu interferon pegylat alfa 2b si ribavirina in hepatita cronica C L. Gheorghe, I. Simionov, R. Vadan, I. Iova, N. Sablici, I. Constantinescu, C. Gheorghe. Combined treatment with PegIntron and Rebetol in patients with chronic hepatitis C. Rom J Gastroenterol 2002; 11 (Suppl 1): 115-116 6. Importanta si principiile terapiei nutritionale in hepatologie si gastroenterologie L. Gheorghe, C. Gheorghe, R. Vadan, C. Croitoru, C. Mihaila, I. Bancila, I. Iova. Effect of high-calorie, high-protein diet in cirrhotic patients with hepatic encephalopathy. J

21 Hepatol 2002; 36 (Suppl 1): 171 (605) L. Gheorghe, Razvan Iacob, Roxana Vadan, Speranta Iacob, Cristian Gheorghe. Improvement of hepatic encephalopathy using a modified high-calorie high-protein diet. Rom J Gastroenterol 2005; 14: 231-238 7. Studiu pilot in Romania efectuat pe 65 de pacienti asupra eficientei si tolerabilitatii terapiei combinate cu interferon pegylat alfa 2a si ribavirina in hepatita cronica C L. Gheorghe, S. Iacob, R. Iacob, M. Diculescu, C. Gheorghe, I. Constantinescu, A. Ionescu, M. Ciocarlan. Profilul reactiilor adverse si tolerabilitatea Peginterferonului alfa2a in combinatie cu ribavirina comparativ cu interferonul alfa-2a standard si ribavirina la pacientii cu hepatita cronica C. Rom J Gastroenterol 2003; 12 (Suppl 1): 15 L. Gheorghe, M. Grigorescu, S. Iacob, D. Damian, C. Gheorghe, R. Iacob, I. Simionov, R. Vadan, I. Parvulescu, I. Bancila. Effectiveness and tolerability of pegylated interferon -2a and ribavirin combination therapy in Romanian patients with chronic hepatitis C: from clinical trials to clinical practice. Rom J Gastroenterol 2005; 14: 109-115 8. Tratamentul hepatitei C recurente post-transplant: prima lucrare cu acest subiect prezentata in Romania in conditiile in care experienta internationala este limitata L. Gheorghe. Antiviral therapy peri-liver transplantation 5-th Symposium and Postgraduate Course of the International Association of Surgeons and Gastroenterologists (IASG), 9-11 aprilie 2003 urmata de: L. Gheorghe, R. Vadan, V. Herlea, C. Gheorghe, D. Hrehoret, S. Iacob, I. Popescu. Hepatita cronica recurenta VHC post-transplant hepatic. Rom J Gastroenterol 2003; 12 (Suppl 1): 93 9. Frecventa si factorii predictivi pentru sindromul de overlap in bolile autoimune hepatice. L. Gheorghe, S. Iacob, C. Gheorghe, R. Iacob, I. Simionov, R. Vadan, G. Becheanu, I. Parvulescu, C. Toader. Frequency and predictive factors for overlap syndrome between autoimmune hepatitis and cholestatic liver disease. Eur J Gastroenterol Hepatol 2004; 16: 585-592 10. Diagnosticul si managementul pacientilor cu boala Wilson L. Gheorghe, I. Popescu, S. Iacob, C. Gheorghe, R. Vadan, A. Constantinescu, R. Iacob, G. Becheanu, C. Angelescu, M. Diculescu. Wilsons disease: a challenge of diagnosis. The 5-years experience of a tertiary centre. Rom J Gastroenterol 2004; 13: 179-185 11. Managementul pacientilor aflati pe lista de asteptare pentru transplant hepatic L. Gheorghe, I. Popescu, R. Iacob, S. Iacob, C. Gheorghe. Predictors of death on the waiting list for liver transplantation characterized by a long waiting time. Transplant International 2005; 18: 572-576 12. Istoria naturala a cirozei hepatice B plus D L. Gheorghe, Speranta Iacob, Iulia Simionov, Roxana Vadan, Cristian Gheorghe, Razvan Iacob, Iulia Parvulescu, Ileana Constantinescu. Natural history of compensated hepatitis B and D viruses cirrhosis. Rom J Gastroenterol 2005; 14: 329-336