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WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

LEARNING ABOUT HEART FAILURE (HF)


Heart failure is a common and potentially life-threatening condition, affecting more than 20 million people worldwide however few people fully understand heart failure
WHAT IS HEART FAILURE?
Select from options A to D below

Where the heart cannot pump enough blood around the body

Where the hearts electrical system beats irregularly

Where blocked or clogged arteries limit flow of blood to the heart

Where the heart is starved of blood and oxygen, usually by a clot

Harrisons Principles of Internal Medicine, Seventeenth Edition pages 1442 - 1455. Zannad F. et al. Heart failure burden and therapy. Europace . 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

LEARNING ABOUT HEART FAILURE (HF)


Heart failure is a common and potentially life-threatening condition, affecting more than 20 million people worldwide however few people fully understand heart failure
WHAT IS HEART FAILURE?
Select from options A to D below

Where the heart cannot pump enough blood around the body This is known as heart failure

Correct
A

Where the hearts electrical system beats irregularly

Where blocked or clogged arteries limit flow of blood to the heart

Where the heart is starved of blood and oxygen, usually by a clot

Harrisons Principles of Internal Medicine, Seventeenth Edition pages 1442 - 1455. Zannad F. et al. Heart failure burden and therapy. Europace . 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

LEARNING ABOUT HEART FAILURE (HF)


Heart failure is a common and potentially life-threatening condition, affecting more than 20 million people worldwide however few people fully understand heart failure
WHAT IS HEART FAILURE?
Select from options A to D below

Where the heart cannot pump enough blood around the body

Where the hearts electrical system beats irregularly This is known as arrhythmia

Incorrect
B

Where blocked or clogged arteries limit flow of blood to the heart

Where the heart is starved of blood and oxygen, usually by a clot

Harrisons Principles of Internal Medicine, Seventeenth Edition pages 1442 - 1455. Zannad F. et al. Heart failure burden and therapy. Europace . 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

LEARNING ABOUT HEART FAILURE (HF)


Heart failure is a common and potentially life-threatening condition, affecting more than 20 million people worldwide however few people fully understand heart failure
WHAT IS HEART FAILURE?
Select from options A to D below

Plaque

Where the heart cannot pump enough blood around the body

Where the hearts electrical system beats irregularly

Where blocked or clogged arteries limit flow of blood to the heart This is known as atherosclerosis

Incorrect
C

Where the heart is starved of blood and oxygen, usually by a clot

Harrisons Principles of Internal Medicine, Seventeenth Edition pages 1442 - 1455. Zannad F. et al. Heart failure burden and therapy. Europace . 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

LEARNING ABOUT HEART FAILURE (HF)


Heart failure is a common and potentially life-threatening condition, affecting more than 20 million people worldwide however few people fully understand heart failure
WHAT IS HEART FAILURE?
Select from options A to D below

Where the heart cannot pump enough blood around the body

Where the hearts electrical system beats irregularly

Where blocked or clogged arteries limit flow of blood to the heart

Where the heart is starved of blood and oxygen, usually by a clot This is known as a heart attack

Incorrect
D

Harrisons Principles of Internal Medicine, Seventeenth Edition pages 1442 - 1455. Zannad F. et al. Heart failure burden and therapy. Europace . 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

COMMON CAUSES OF HEART FAILURE (HF)


In most cases, heart failure does not have a single cause there are a number of conditions that may damage your heart and that could lead you to be diagnosed with heart failure
Select the silhouettes below

BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

COMMON CAUSES OF HEART FAILURE (HF)


In most cases, heart failure does not have a single cause there are a number of conditions that may damage your heart and that could lead you to be diagnosed with heart failure
Select the silhouettes below

Excess alcohol

BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

COMMON CAUSES OF HEART FAILURE (HF)


In most cases, heart failure does not have a single cause there are a number of conditions that may damage your heart and that could lead you to be diagnosed with heart failure
Select the silhouettes below

Damaged heart valves

BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

COMMON CAUSES OF HEART FAILURE (HF)


In most cases, heart failure does not have a single cause there are a number of conditions that may damage your heart and that could lead you to be diagnosed with heart failure
Select the silhouettes below

High blood pressure

BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

COMMON CAUSES OF HEART FAILURE (HF)


In most cases, heart failure does not have a single cause there are a number of conditions that may damage your heart and that could lead you to be diagnosed with heart failure
Select the silhouettes below

Arrhythmia/ irregular heartbeat

BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

COMMON CAUSES OF HEART FAILURE (HF)


In most cases, heart failure does not have a single cause there are a number of conditions that may damage your heart and that could lead you to be diagnosed with heart failure
Select the silhouettes below

Atherosclerosis/blocked or clogged arteries

BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

COMMON CAUSES OF HEART FAILURE (HF)


In most cases, heart failure does not have a single cause there are a number of conditions that may damage your heart and that could lead you to be diagnosed with heart failure
Select the silhouettes below

Inflammation of the heart muscle

BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

COMMON CAUSES OF HEART FAILURE (HF)


In most cases, heart failure does not have a single cause there are a number of conditions that may damage your heart and that could lead you to be diagnosed with heart failure
Select the silhouettes below

Heart attack

BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

COMMON CAUSES OF HEART FAILURE (HF)


In most cases, heart failure does not have a single cause there are a number of conditions that may damage your heart and that could lead you to be diagnosed with heart failure
Select the silhouettes below

Weak heart muscle

BHF website http://bit.ly/g1fOpW Accessed August 2013. AHA website http://bit.ly/d54MDM Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?


A B C

1 in 500 people 1 in 50 people 1 in 5 people


FIND OUT MORE
For people aged 40 and older, the lifetime risk of developing heart failure is 1 in 5

Heart failure is a major and growing public health problem select the silhouettes below

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?


A B C

1 in 500 people 1 in 50 people 1 in 5 people


FIND OUT MORE

0.2%

For people aged 40 and older, the lifetime risk of developing heart failure is 1 in 5

Incorrect

Heart failure is a major and growing public health problem select the silhouettes below

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?


A B C

1 in 500 people 1 in 50 people 1 in 5 people


FIND OUT MORE

2%

For people aged 40 and older, the lifetime risk of developing heart failure is 1 in 5

Incorrect

Heart failure is a major and growing public health problem select the silhouettes below

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?


A B C

1 in 500 people 1 in 50 people 1 in 5 people


FIND OUT MORE

20%

For aged 7080, the older, lifetime For people people aged 40 and risk of developing failure the lifetime risk ofheart developing is up to 1 in 5 in Europe

Correct

heart failure is 1 in 5

Heart failure is a major and growing public health problem select the silhouettes below

Dickstein et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008. European Heart Journal . 2008;29:2388442

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?


A B C

1 in 500 people 1 in 50 people 1 in 5 people


FIND OUT MORE
For people aged 40 and older, the lifetime risk of developing heart failure is 1 in 5

Heart failure is a major and growing public health problem select the silhouettes below

More than 20 million people suffer from heart failure worldwide and this number is increasing
Zannad F. et al. Heart failure burden and therapy. Europace. 2009;11:v1-v9. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73

20

million

worldwide

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?


A B C

1 in 500 people 1 in 50 people 1 in 5 people


FIND OUT MORE
For people aged 40 and older, the lifetime risk of developing heart failure is 1 in 5

Heart failure is a major and growing public health problem select the silhouettes below

8,000,000
new cases by

2030

By 2030, over eight million people in the United States (1 in every 33) will have heart failure

Heidenreich et al. Forecasting the Impact of Heart Failure in the United States. Circulation: Heart Failure . 2013;6:606-619

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

WHAT IS THE LIFE TIME RISK OF HEART FAILURE (HF)?


A B C

1 in 500 people 1 in 50 people 1 in 5 people


FIND OUT MORE
For people aged 40 and older, the lifetime risk of developing heart failure is 1 in 5

Heart failure is a major and growing public health problem select the silhouettes below

An aging population and an increase in the number of people surviving heart attacks both contribute to the rise in heart failure
Schocken et al. AHA Scientific Statement: Prevention of Heart Failure. Circulation . 2008;117:2544-2565. Mosterd A, Hoes, A. Clinical epidemiology of heart failure. Heart . 2007;93:1137-1146

c a t re a ta s ck ed su he rv ar iv t al

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In

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

ACUTE HEART FAILURE (AHF) EPISODES A DOWNWARD SPIRAL


Heart failure is often fatal when patients have one or repeated AHFepisodes
SELECT NUMBERS TO VIEW

It felt like I was drowning

1
DOWNWARD SPIRAL

Every episode results in worsening health and damage to vital organs, such as the heart and kidneys, which decreases the chance of the patient surviving another episode

Zannad F. et al. Heart failure burden and therapy. Europace . 2009;11:v1-v9. Irish Heart Foundation. Living well with heart failure patient booklet http://bit.ly/11FDqR6 Accessed August 2013. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73. Gheorghiade M et al. Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology . 2013;61(4):391-403

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

ACUTE HEART FAILURE (AHF) EPISODES A DOWNWARD SPIRAL


Heart failure is often fatal when patients have one or repeated AHFepisodes
SELECT NUMBERS TO VIEW
SYMPTOMS
As an AHF episode approaches, patients experience:

Breathlessness 2 Incapacitation 3 Fluid build-up 4 Weight gain


1

It felt like I was drowning

1
DOWNWARD SPIRAL

Every episode results in worsening health and damage to vital organs, such as the heart and kidneys, which decreases the chance of the patient surviving another episode

Zannad F. et al. Heart failure burden and therapy. Europace . 2009;11:v1-v9. Irish Heart Foundation. Living well with heart failure patient booklet http://bit.ly/11FDqR6 Accessed August 2013. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73. Gheorghiade M et al. Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology . 2013;61(4):391-403. Mosterd A, Hoes, A. Clinical epidemiology of heart failure. Heart . 2007;93:1137-1146

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

ACUTE HEART FAILURE (AHF) EPISODES A DOWNWARD SPIRAL


Heart failure is often fatal when patients have one or repeated AHFepisodes
SELECT NUMBERS TO VIEW
SYMPTOMS
As an AHF episode approaches, patients experience:

Breathlessness 2 Incapacitation 3 Fluid build-up 4 Weight gain


1

It felt like I was drowning

Patients rushed to the emergency room for urgent treatment

1
DOWNWARD SPIRAL

Every episode results in worsening health and damage to vital organs, such as the heart and kidneys, which decreases the chance of the patient surviving another episode

Zannad F. et al. Heart failure burden and therapy. Europace . 2009;11:v1-v9. Irish Heart Foundation. Living well with heart failure patient booklet http://bit.ly/11FDqR6 Accessed August 2013. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73. Gheorghiade M et al. Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology . 2013;61(4):391-403. Mosterd A, Hoes, A. Clinical epidemiology of heart failure. Heart . 2007;93:1137-1146. Felker et al. Clinical trial of pharmacological therapies in acute heart failure syndromes. Circulation: Heart Failure . 2010;3:314-325

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

ACUTE HEART FAILURE (AHF) EPISODES A DOWNWARD SPIRAL


Heart failure is often fatal when patients have one or repeated AHFepisodes
SELECT NUMBERS TO VIEW
SYMPTOMS
As an AHF episode approaches, patients experience:

Breathlessness 2 Incapacitation 3 Fluid build-up 4 Weight gain


1

It felt like I was drowning

Patients rushed to the emergency room for urgent treatment

1
DOWNWARD SPIRAL

Every episode results in worsening health and damage to vital organs, such as the heart and kidneys, which decreases the chance of the patient surviving another episode

3
of patients do not survive the initial episode

34%

Zannad F. et al. Heart failure burden and therapy. Europace . 2009;11:v1-v9. Irish Heart Foundation. Living well with heart failure patient booklet http://bit.ly/11FDqR6 Accessed August 2013. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73. Gheorghiade M et al. Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology . 2013;61(4):391-403. Mosterd A, Hoes, A. Clinical epidemiology of heart failure. Heart . 2007;93:1137-1146. Felker et al. Clinical trial of pharmacological therapies in acute heart failure syndromes. Circulation: Heart Failure . 2010;3:314-325. Weintraub et al. Acute heart failure syndromes. Circulation . 2010;122:1975-1996

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

ACUTE HEART FAILURE (AHF) EPISODES A DOWNWARD SPIRAL


Heart failure is often fatal when patients have one or repeated AHFepisodes
SELECT NUMBERS TO VIEW
SYMPTOMS
As an AHF episode approaches, patients experience:

Breathlessness 2 Incapacitation 3 Fluid build-up 4 Weight gain


1

It felt like I was drowning

Patients rushed to the emergency room for urgent treatment

1
DOWNWARD SPIRAL

of patients die within 1 year after experiencing an AHF episode

2030%

Every episode results in worsening health and damage to vital organs, such as the heart and kidneys, which decreases the chance of the patient surviving another episode

3
of patients do not survive the initial episode

34%

Zannad F. et al. Heart failure burden and therapy. Europace . 2009;11:v1-v9. Irish Heart Foundation. Living well with heart failure patient booklet http://bit.ly/11FDqR6 Accessed August 2013. Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73. Gheorghiade M et al. Rehospitalization for heart failure: problems and perspectives. Journal of the American College of Cardiology . 2013;61(4):391-403. Mosterd A, Hoes, A. Clinical epidemiology of heart failure. Heart . 2007;93:1137-1146. Felker et al. Clinical trial of pharmacological therapies in acute heart failure syndromes. Circulation: Heart Failure . 2010;3:314-325. Weintraub et al. Acute heart failure syndromes. Circulation . 2010;122:1975-1996. Harrisons Principles of Internal Medicine, Seventeenth Edition pages 1442 - 1455. National heart failure audit: April 2010 March 2011, NICOR and The British Society for Heart Failure, commissioned by the Healthcare Quality Improvement Partnership (HQIP). OConnor M et al. Causes of death and rehospitalization in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction. American Heart Journal . 2010;159(5): 842-849. Hunt S et al. Focused update incorporated into the ACC/AHA 2005. Circulation . 2009;119:e391-e479

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

Patients with acute heart failure may suffer an increasing number of episodes as their condition deteriorates, leading to frequent hospitalization, a downward spiral in health, and a high rate of mortality

FUNCTION AND QUALITY OF LIFE

MORTALITY

Progressive decline in the function of the heart


20 to 30% of patients die within 1 year after experiencing an AHF episode and 3-4% do not survive the initial episode

Acute episode

Harrisons Principles of Internal Medicine, Seventeenth Edition pages 1442 - 1455. National heart failure audit: April 2010 March 2011, NICOR and The British Society for Heart Failure, commissioned by the Healthcare Quality Improvement Partnership (HQIP). OConnor M et al. Causes of death and rehospitalization in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction. American Heart Journal . 2010;159(5): 842-849. Hunt S et al. Focused update incorporated into the ACC/AHA 2005. Circulation . 2009;119:e391-e479. Weintraub et al. Acute heart failure syndromes. Circulation . 2010;122:1975-1996. Alla et al. Epidemiology of acute heart failure syndromes. Heart Fail Rev . 2007;12:915. Cleland et al. The EuroHeart Failure survey programme a survey on the quality of care among patients with heart failure in Europe. European Heart Journal . 2003;24:442636. Gheorghiade et al. Pathophysiologic targets in the early phase of acute heart failure syndromes. American Journal of Cardiology . 2005;96:11G17G

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

MILLIONS OF ACUTE HEART FAILURE (AHF) EPISODES HAPPEN EVERY YEAR

Each year around acute heart failure (AHF) episodes happen in the US and EU alone; this is expected to increase further as the population ages.

3.5 million

If everyone in the world with heart failure gathered in one country, it would be about the population of Australia

Lined up end to end, the number of ambulances for every AHF patient taken to the hospital in a single year would stretch nearly 21,000 km almost as long as the Great Wall of China

21,000 km

Gheorghiade M, Pang P. Acute heart failure syndromes. Journal of the American College of Cardiology . 2009;53(7):557-73

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

HEART FAILURE REPRESENTS A MAJOR AND GROWING HEALTH ECONOMIC BURDEN


Acute heart failure is the most common cause of hospitalization in patients over 65 years
What percentage of all healthcare expenditure in developed countries is thought to be spent on heart failure?

What is the estimated global cost of heart failure per year?

What percentage of the cost of heart failure is due to pharmacological treatment?

Answer

Answer

Answer

Lloyd-Jones et al. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation . 2010;121:e46-215. Neumann et al. Heart failure: the commonest reason for hospitalization in Germany medical and economic perspectives. Dtsch Arztebl Int . 2009;106:26975. Berry et al. Economics of chronic heart failure. European Journal of Heart Failure . 2001;3:283-291. Stewart et al. The current cost of heart failure to the National Health Service in the UK. European Journal of Heart Failure . 2002;4:361-371. Forman et al. Influence of age on the management of heart failure. American Heart Journal . 2009;157:1010-1017. Healthcare Cost and Utilization Project 2009 http://1.usa.gov/s083eF Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

HEART FAILURE REPRESENTS A MAJOR AND GROWING HEALTH ECONOMIC BURDEN


Acute heart failure is the most common cause of hospitalization in patients over 65 years
What percentage of all healthcare expenditure in developed countries is thought to be spent on heart failure?

What is the estimated global cost of heart failure per year?

What percentage of the cost of heart failure is due to pharmacological treatment?

Answer

Answer

Answer

and growing

45 billion

Over

Lloyd-Jones et al. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation . 2010;121:e46-215. Neumann et al. Heart failure: the commonest reason for hospitalization in Germany medical and economic perspectives. Dtsch Arztebl Int . 2009;106:26975. Berry et al. Economics of chronic heart failure. European Journal of Heart Failure . 2001;3:283-291. Stewart et al. The current cost of heart failure to the National Health Service in the UK. European Journal of Heart Failure . 2002;4:361-371. Forman et al. Influence of age on the management of heart failure. American Heart Journal . 2009;157:1010-1017. Healthcare Cost and Utilization Project 2009 http://1.usa.gov/s083eF Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

HEART FAILURE REPRESENTS A MAJOR AND GROWING HEALTH ECONOMIC BURDEN


Acute heart failure is the most common cause of hospitalization in patients over 65 years
What percentage of all healthcare expenditure in developed countries is thought to be spent on heart failure?

What is the estimated global cost of heart failure per year?

What percentage of the cost of heart failure is due to pharmacological treatment?

Answer

Answer

Answer

of total healthcare budget in many countries is spent on the management of heart failure

~ 2%

Lloyd-Jones et al. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation . 2010;121:e46-215. Neumann et al. Heart failure: the commonest reason for hospitalization in Germany medical and economic perspectives. Dtsch Arztebl Int . 2009;106:26975. Berry et al. Economics of chronic heart failure. European Journal of Heart Failure . 2001;3:283-291. Stewart et al. The current cost of heart failure to the National Health Service in the UK. European Journal of Heart Failure . 2002;4:361-371. Forman et al. Influence of age on the management of heart failure. American Heart Journal . 2009;157:1010-1017. Healthcare Cost and Utilization Project 2009 http://1.usa.gov/s083eF Accessed August 2013. Dickstein et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008. European Heart Journal . 2008;29;23882442

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

HEART FAILURE REPRESENTS A MAJOR AND GROWING HEALTH ECONOMIC BURDEN


Acute heart failure is the most common cause of hospitalization in patients over 65 years
What percentage of all healthcare expenditure in developed countries is thought to be spent on heart failure?

What is the estimated global cost of heart failure per year?

What percentage of the cost of heart failure is due to pharmacological treatment?

Answer

Answer

Answer

<10%
Lloyd-Jones et al. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation . 2010;121:e46-215. Neumann et al. Heart failure: the commonest reason for hospitalization in Germany medical and economic perspectives. Dtsch Arztebl Int . 2009;106:26975. Berry et al. Economics of chronic heart failure. European Journal of Heart Failure . 2001;3:283-291. Stewart et al. The current cost of heart failure to the National Health Service in the UK. European Journal of Heart Failure . 2002;4:361-371. Forman et al. Influence of age on the management of heart failure. American Heart Journal . 2009;157:1010-1017. Healthcare Cost and Utilization Project 2009 http://1.usa.gov/s083eF Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

MYTH OR FACT
Cancer
deaths

Heart failure
deaths

Acute heart failure patients have a better prognosis than cancer patients

The signs and symptoms of heart failure are easy to recognise

Heart failure affects mostly men

Myth or Fact ?

Myth or Fact ?

Myth or Fact ?

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

MYTH OR FACT
Heart failure
deaths

Cancer
deaths

Acute heart failure patients have a better prognosis than cancer patients

The signs and symptoms of heart failure are easy to recognise

Heart failure affects mostly men

Myth or Fact ?

Myth or Fact ?

Myth or Fact ?

Myth
Acute heart failure causes more deaths than some advanced cancers, including breast and bowel cancer

Stewart et al. More malignant than cancer? Five-year survival following a first admission for heart failure. European Journal of Heart Failure . 2001;3:315-322

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

MYTH OR FACT
Cancer
deaths

Heart failure
deaths

Acute heart failure patients have a better prognosis than cancer patients

The signs and symptoms of heart failure are easy to recognise

Heart failure affects mostly men

Myth or Fact ?

Myth or Fact ?

Myth or Fact ?

Myth
Despite the incidence, only 3% of the general public in Europe can identify the signs and symptoms of heart failure

Remme et al. Public awareness of heart failure in Europe: first results from SHAPE. European Heart Journal . 2005;26:2413-2421

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

MYTH OR FACT
Cancer
deaths

Heart failure
deaths

Acute heart failure patients have a better prognosis than cancer patients

The signs and symptoms of heart failure are easy to recognise

Heart failure affects mostly men

Myth or Fact ?

Myth or Fact ?

Myth or Fact ?

Myth
There is a widespread misconception that heart failure is a man's disease. But heart failure is also a devastating health problem for women
Cleveland clinic: Heart Failure & women http://bit.ly/qw4pEv Accessed August 2013

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

NO TREATMENT BREAKTHROUGHS IN 20 YEARS


Despite significant progress in treating other heart conditions, there have been no major developments in treatment for patients with acute heart failure for two decades Commonly used medicines for AHF treat only immediate symptoms and have not been proven to have an impact on longer-term outcomes
DISCOVER CURRENTLY AVAILABLE TREATMENT OPTIONS

TREATMENT GOALS CURRENT TREATMENT OPTIONS

Option

Option

Option

Cowie M et al. Acute heart failure a call to action. British Journal of Cardiology . 2013;20(suppl 2):S1-S11. Hunt S et al. Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. Circulation . 2009;119:e391-e479. McMurray et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. European Heart Journal . 2012;33:1787-1847. Gheorghiade et al. Acute Heart Failure Syndromes: Current State and Framework for Future Research. Circulation . 2005;112:3958-3968

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

NO TREATMENT BREAKTHROUGHS IN 20 YEARS


Despite significant progress in treating other heart conditions, there have been no major developments in treatment for patients with acute heart failure for two decades Commonly used medicines for AHF treat only immediate symptoms and have not been proven to have an impact on longer-term outcomes
DISCOVER CURRENTLY AVAILABLE TREATMENT OPTIONS

TREATMENT GOALS CURRENT TREATMENT OPTIONS

IMMEDIATE: Option Treat symptoms Help patients breathe Reduce fluid build-up Diuretics Vasodilators Oxygen therapy Inotropes

Option

Option

Cowie M et al. Acute heart failure a call to action. British Journal of Cardiology . 2013;20(suppl 2):S1-S11. Hunt S et al. Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. Circulation . 2009;119:e391-e479. McMurray et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. European Heart Journal . 2012;33:1787-1847. Gheorghiade et al. Acute Heart Failure Syndromes: Current State and Framework for Future Research. Circulation . 2005;112:3958-3968

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

NO TREATMENT BREAKTHROUGHS IN 20 YEARS


Despite significant progress in treating other heart conditions, there have been no major developments in treatment for patients with acute heart failure for two decades Commonly used medicines for AHF treat only immediate symptoms and have not been proven to have an impact on longer-term outcomes
DISCOVER CURRENTLY AVAILABLE TREATMENT OPTIONS

TREATMENT GOALS CURRENT TREATMENT OPTIONS

Option

Limit cardiac and renal damage

Option

Option

No therapies currently available

Cowie M et al. Acute heart failure a call to action. British Journal of Cardiology . 2013;20(suppl 2):S1-S11. Hunt S et al. Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. Circulation . 2009;119:e391-e479. McMurray et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. European Heart Journal . 2012;33:1787-1847. Gheorghiade et al. Acute Heart Failure Syndromes: Current State and Framework for Future Research. Circulation . 2005;112:3958-3968

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

NO TREATMENT BREAKTHROUGHS IN 20 YEARS


Despite significant progress in treating other heart conditions, there have been no major developments in treatment for patients with acute heart failure for two decades Commonly used medicines for AHF treat only immediate symptoms and have not been proven to have an impact on longer-term outcomes
DISCOVER CURRENTLY AVAILABLE TREATMENT OPTIONS

TREATMENT GOALS CURRENT TREATMENT OPTIONS

Option

Option

LONG TERM: Option Improve survival and organ protection

No therapies currently available

Cowie M et al. Acute heart failure a call to action. British Journal of Cardiology . 2013;20(suppl 2):S1-S11. Hunt S et al. Focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults. Circulation . 2009;119:e391-e479. McMurray et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. European Heart Journal . 2012;33:1787-1847. Gheorghiade et al. Acute Heart Failure Syndromes: Current State and Framework for Future Research. Circulation . 2005;112:3958-3968

WHAT IS HEART FAILURE?

COMMON CAUSES

PREVALENCE & INCIDENCE

SIGNS & SYMPTOMS

MORTALITY RATES

ANNUAL STATISTICS

COST

MYTH OR FACT

TREATMENT

URGENT NEED

MORE NEEDS TO BE DONE


There is an urgent need for new treatments to help relieve symptoms and increase patients life expectancy by protecting vital organs against life-threatening damage during an AHF episode

NEW TREATMENTS

RELIEVE SYMPTOMS

PROTECT ORGANS

INCREASE LIFE EXPECTANCY

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