DRUG STUDY Drug Name Dosage, route, Frequency

Hydrocortisone 100 mg IV stat Adjunct treatment for ulcerative colitis and proctitis

Indication

Mechanism of Action
Decreases inflammation, leukocyte lysosomal membranes; response; stimulates bone marrow; and influences protein, fat and carbohydrate metabolism.

Adverse Effect

Drug Interaction

Contraindications

Nursing Intervention

CNS: Insomia CV: hypertension ulceration, GI irritation Hyperglycemia

DRUG: NSAIDS Cyclosporine Oral anticoagulants Thiazide diuretics Skin test antigens HERB: Echinacea Ginseng

Contraindicated in patients: Hypersensitive to drugs ot its ingredients, in those with systemic fungal infections, in those receiving immunosuppressi ve doses together with live vaccines. With recent MI With GI ulcer, renal disease, hypertension, osteoporosis, diabetes mellitus, hypothyroidism, cirrhosis, diverticulitis, nonspecific ulcerative colitis ,

1.Warn patient on long therapy about cushingoid effects. 2.Teach patient and significant others signs and symptoms of early adrenal insufficiency: fatigue, muscle weakness, joint pain, fever, anorexia, nausea, shortness of breath, dizziness and fainting. 3.Warn patiend and SO about easy brusing. 4.Advise patient and So to have the patient

mainly by stabilizing GI: peptic

suppresses immune Metablolic:

active hepatitis, lactation, recent intestinal anastomoses,, thromboembolic disorders, seizures, myasthemia gravis, heart failure, tb, ocular herpes simplex, emotional instability, and psychotic tendencies.

periodic eye examination. 5.Inform patient and So to avoid the patient from infections such as chickenpox and measles.

DRUG STUDY Drug Name Dosage, route, frequency

Carvedilol 6.5 mg PO OD Hypertension Angina pectoris

Indication

Mechanism of Action
Nonselectice beta blocker with alphablocking activity

Adverse Effect

Drug Interaction

Contraindications

Nursing Interventions

CNS: Fatigue, pain CV: Chest pain Respiratory: Cough, dyspnea

DRUG: Amiodarone Cathecholamine depleting drugs Cimetidine Cyclosporine Digoxin Diltiazem, verapamil Fluxetine, paroxetine, propafenone, quinidine

Contraindicated in patients: Hypersensitive to drug and in those decompensated cardiac requiring I.V. inotropic therapy. With bronchial asthma or related bronchospatic condition, second or third Av block, sick cinus syndrome, cardiogenic shock, severs brady cardia, or symptomatic hepatic impairment. Thyroid disease Younger than 18.

1.Inform patient that improvement of heart failure may occur several weeks. 2.Inform patient that may experience hypotesion when standing. 3.Advise to stand slowly.

DRUG STUDY Drug Name Dosage, route, frequency

Candesartan 5mg tab PO OD Hypertension

Indication

Mechanism of Action
Inhibits vasoconstrictive action of angiotensin II receptor on the surface of vascular smooth muscle and other tissue cell.

Adverse Effect

Drug Interaction

Contraindications

Nursing Interventions

CNS: weakness CV: chest pain GI: abdominal pain Musculoskeletal: arthgalia Respiratory: coughing

DRUG: Potassium sparring, potassium supplement DRUG-HERB Ma-huang DRUG-FOOD: Salt substitute containing potassium

Contraindicated in patients: Hypersensitive to drug and its component. Whose renal function depends on the rennin angiotensin aldosterone system because of risk oliguria and progressive azotemia with acute renal failure or death. Who are pregnant. Volume or salt depleted.

1.If hypotension occurs after a dose of candesartan, place patient in supine position and if needed give an I.V. infusion of normal saline solution. 2. Monitor therapeutic response and the occurrence of adverse reaction and in those with renal disease. 3.Inform patient to report reactions without delay. 4.Medication may be taken without regards to meals.

DRUG STUDY Drug Name Dosage, route, frequency

Azithromycin 500 mg IV OD Community acquired pneumonia

Indication

Mechanism of Action
Binds to the 50S subunit ribosomes, blocking protein synthesis; bacreiostatic or bacteriacidal, depending on concentration.

Adverse Effect

Drug Interaction

Contraindications

Nursing Interventions

CNS: fatigue CV: chest pain GI: abdominal pain

DRUG: Antacids Carbazepine, cyclosporine, phenytoin Digoxin Ergotamine Theophylline Triazolam Warfarin FOOD: Any food Lifestyle: Sun exposue

Contraindicated in patients: Hypersensitive to azithromycin or other macrolides. With impaired hepatic functions.

1.Avoid giving medication with antacids. 2.Monitor patient for superinfection. Drug may cause growth of nonsusceptible bacteria or fungi. 3.Instruct patient and So that may be taken with or without food.

DRUG STUDY Drug Name Dosage, route, frequency

Pantoprazole 40 mg IV OD Short term treatment of GERD linked to history of erosive esophagitis.

Indication

Mechanism of Action
Inhibits proton pump activity by binding to hydrogenpotassium adenosine triphosphate, located at secretory surface of gastric parietal cells, to suppress gastric acid secretion.

Adverse Effect

Drug Interaction

Contraindications

Nursing Interventions

CV: chest pain GI: abdominal pain Musculoskeletal: back pain Respiratory: cough

DRUG: Ampicillin HERB: St. Johns wort Lifestyle: Sunlight

Contraindicated in patients with: Hypersensitive to any component of the formulation. Safety and efficacyof using the IV formulation to start therapy for GERD are unknown.

1.Advise patient and SO that medication may be taken without regard to meals. 2.Tell patient not to swallow tablet and not to crush crush, split, or chew. 3.Tell patient that antacids does not affect pantoprazole.

DRUG STUDY Drug Name Dosage, route, frequency

Furosemide 40 mg IV OD Hypertension

Indication

Mechanism of Action
A poten loop diuretic tha inhibits sodium chloride reabsorption at the proximal and distal tubules and the ascending loop of henle.

Adverse Effect

Drug Interaction

Contraindications

Nursing Interventions

CNS: weakness GI: abdominal discomfort and pain

DRUG: Aminoglycosides Cariac glycosides Ethacrynic acid Lithium NSAIDs Phenytoin Salicylates Sucralfate HERB: Aloe Dandelion Ginseng Licorice LIFESTYLE: Sun exposure

Contraindicated in patients: drug and in those with anuria, With hepatic cirrhosis and in those allergic to sulfonamides.

1. Monitor intake and output and electrolyte. 2. Watch signs of hypokalemia, such as muscle weakness and cramps. 3. Monitor glucose level. 4. Advise patient to take drug with food too prevent GI upset, and to take drug in morning to prevent nighttime urination. 5. Inform patient of possible need for potassium or magnesium supplement.

antibiotis cisplatin Hypersensitive to

6. Instruct to stand slowly to prevent dizzinessand to limit alcohol intake and strenuous exercise in hot weather to avoid worsening dizziness upon standing quickly. 7. Advice patient to report immediately report ringin in ears, severe abdominal pain, or sore throat or fever, these symptoms may indicate furosemide toxicity. 8. Inform patient and SO to avoid direct sunlight.