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Examinations summer 2014 Registration deadline for examinations Examination session summer 2014 16.03.2014 04.08.2014 29.08.

2014 Su Mo / Fr

Semester dates Classes begin End of semester 17.02.2014 30.05.2014 Mo Fr

529-0732-00L Proteins and Lipids


Semester Lecturers Periodicity Language of instruction Spring Semester 2013 D. Hilvert yearly course English

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Abstract Objective Content Literature

An overview of the relationship between protein sequence, conformation and function. Overview of the relationship between protein sequence, conformation and function. General Literature: - T.E. Creighton: Proteins: Structures and Molecular Properties, 2nd Edition, H.W. Freeman and Company, New York, 1993. - C. Branden, J. Tooze , Introduction to Protein Structure, Garland Publishing, New York, 1991. - J. M. Berg, J. L. Tymoczko, L. Stryer: Biochemistry, 5th edition, H.W. Freeman and Company, New York, 2002. - G.A. Petsko, D. Ringe: Protein Structure and Function, New Science Press Ltd., London, 2004. Original Literature: Citations from the original literature relevant to the individual lectures will be assigned weekly.

Proteins, structures and properties, (bio)synthesis of polypeptides, protein folding and design, protein engineering, chemical modification of proteins, proteomi

529-0191-01L Renewable Energy Technologies II, Energy Storage and Conversion


Semester Lecturers Periodicity Language of instruction Comment Spring Semester 2013 T. Schmidt yearly course English

The lectures Renewable Energy Technologies I (529-0193-00L) and Renewable Energy Technologies II (529-0191-01L) can be taken independently from one

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Abstract

Swiss energy system. Energy conversion efficiency. Storage: Pumped water, fly wheels, compressed air, electromagnetic. Seasonal heat storage. Hydrogen as e electrolysis; power-to-gas. Fuel cells: fundamentals, components, stacks, systems; portable devices and stationary power generation (CHP). Fuel cell vehicles; storage in batteries. supercapacitors; electromobility.

Objective Literature

Students will recognize the importance of energy storage in an industrial energy system. The efficient generation of electricity from hydrogen in fuel cells, and energy storage in batteries and supercapacitors will be introduced. Students will get an insight into electrochemical energy conversion and storage. - Tester, J.W., Drake, E.M., Golay, M.W., Driscoll, M.J., Peters, W.A.: Sustainable Energy - Choosing Among Options (MIT Press, 2005). - C.H. Hamann, A. Hamnett, W. Vielstich; Electrochemistry Wiley-VCH (2007). Spring Semester 2013 J. A. van Bokhoven, A. Mezzetti, M. Ranocchiari yearly course English

529-0502-00L Catalysis
Semester Lecturers Periodicity Language of instruction

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Abstract Objective Content

Fundamental principles of adsorption and catalysis, physics and chemistry of solid-state surfaces and methods for determining their structure and composition. catalysis with transition-metal complexes. Basic knowledge of heterogeneous and homogeneous catalysis Fundamental principles of adsorption and catalysis, physics and chemistry of solid-state surfaces and methods for determining their structure and composition, and kinetic fundamentals of heterogeneous catalysis (physisorption, chemisorption, kinetic modelling, selectivity, activity, stability), catalyst development and homogeneous catalysis with transition-metal complexes; catalytic reaction cycles and types. A script is available Spring Semester 2013 I. Aeberli, M. B. Zimmermann, F. M. Hilty-Vancura, C. Wolfrum yearly course English

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752-6002-00L Advanced Topics in Nutritional Science

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Abstract Objective Content

The course gives an introduction to dietary recommendations and nutrient requirements at different stages of the life cycle. It also includes lectures on specific vegetarianism and weight loss, as well as important nutrients and their interactions.

The learning objectives are improved student understanding of: 1) the dietary recommendations and nutrient requirements of populations at different stages of t the effect of different diets on health; and 3) certain micronutrients and other nutritionally important food components.

The course gives a brief introduction into different areas of human nutrition. Including: 1) Dietary recommendations and the nutrient requirements at different s cycle, including pregnancy and lactation, childhood and adolescence, adults and elderly. 2) The influence of specific diets (e.g. vegetarianism, weight loss diets Specific nutrients (e.g. iron and biological active ingredients) and their interactions. The lecture details and teaching slides will be available online Nutrition: a lifespan approach by Simon Langley-Evans (will be available as e-book at the ETH library from January 2013) Spring Semester 2013 M.-O. Ebert, P. S. Dittrich yearly course English

Lecture notes Literature Semester Lecturers Periodicity Language of instruction

529-0042-00L Structure Elucidation by NMR; Modern Bioanalytical Methods and Sensors

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Abstract Objective

Structure Elucidation of Organic Molecules by NMR (2h, B. Jaun/M.-O. Ebert) Modern bioanalytical methods and sensors (1h, P. S. Dittrich)

Structure elucidation of organic molecules by advanced 1D and 2D NMR spectroscopy. The emphasis of the course is on the selection of optimal strategies for problem, spectrum interpretation and possible artifacts. Solving and discussing practical case studies/problems demonstrating the individual methods and, in th course, the combined application of several methods form an important part of the course. Introduction in qualtitative and quantitative bioanalytical and diagnostic methods; Analyses of DNA, proteins and cells

Content

Structure determination by multi-pulse and 2D NMR spectroscopy. Homonuclear and heteronuclear shift correlation through scalar coupling; one and two dime

based on the nuclear Overhauser effect. Choosing the best strategy for a given problem, interpretation and artefacts. Immunoassays, spectroscopic and electroanalytical methods used in combination with novel miniaturized platforms (lab-on-chip-technology: biochips and mic Lecture notes Literature Scripts (in english) are distributed in the course T.D.W. Claridge, High Resolution NMR Techniques in Organic Chemistry, Pergamon Press, 1999 (NMR part) Further reading and citations are listed in the script. F. Lottspeich, J. W. Engels: Bioanalytik, Spektrum Akademischer Verlag Further literature will be handed out. Prerequisites / Notice The course language is English. Required level: Courses in analytical chemistry of the 2nd year or equivalent. Spring Semester 2013 M. Scheringer, B. Escher yearly course English Performance assessment Learning materials Courses Restrictions Offered in

701-0998-00L Environmental Assessment of Chemical Products


Semester Lecturers Periodicity Language of instruction Catalogue data

Abstract

Application of methods for chemical risk assessment according to EU technical guidance documents; exposure and effect analysis for different types of chemic chemical properties (QSAR methods), discussion of methods, presentation of alternative methods for the environmental risk assessment of chemicals; discussio objectives of REACH (new chemicals legislation of the EU).

Objective

Experience in using methods for environmental hazard and risk assessment for chemicals, knowledge of the capabilities and limitations of these methods, discu approaches, including REACH, the new chemicals legislation of the EU: 1. presentation of the legal and political context of the assessment of chemical products 2. detailed discussion of assessment methods required for the quantification of emissions, environmental exposure, and effects. Treatment of data gaps and unc evaluation of assessment results. * methods for environmental risk assessment for chemicals (industrial chemicals, not pesticides) according to EU technical guidance documents * exposure analysis: emission patterns, multimedia fate and transport models for quantifying environmental exposure and for calculating persistence and poten transport of chemicals, identification and assessment of transformation products; uncertainty and sensitivity analyses. * effect analysis: estimation of hazard potential, tests for ecotoxicity, dose-effect relationships, extrapolation methods, classification of chemicals according to action.

Content

* assessment methods (deterministic, statistical), risk assessment vs. hazard assessment; PBT assessment (persistence, bioaccumulation, toxicity). Lecture notes Literature Copies of the slides will be distributed. - Van Leeuwen, C.J., Vermeire, T. (Eds.) Risk Assessment of Chemicals: An Introduction. Springer, 2007 (available as an e-book in the ETH main library). - Scheringer, M., Persistence and Spatial Range of Environmental Chemicals. Wiley-VCH, Weinheim, 2002. - Hungerbhler, K.. Mettier, T., Ranke, J., Umweltorientierte chemische Produkte und Prozesse. Springer, 1998. Internet-based working environment:

Prerequisites / Notice

Participants are given access to the virtual working environment "Chemikalienbewertung". This working environment can be reached by any www browser via Support for Collaborative Work http://bscw.let.ethz.ch/bscw). On the BSCW website, further information about the lecture is provided (documents, literature, l exercises are performed in the BSCW environment. Students are assigned to groups in which they work collaboratively on the examples and exercises. Access environment is given by the lecturers and is limited to participants of the lecture (password-protected access).

529-0242-00L Supramolecular Chemistry


Semester Lecturers Periodicity Language of instruction Spring Semester 2013 F. Diederich, Y. Yamakoshi yearly course English

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Abstract

Principles of molecular recognition: cation/anion complexation and their technological applications; complexation of neutral molecules in aqueous solution; no interactions involving aromatic rings; hydrogen bonding; molecular sef-assembly - a chemical approach towards nanostructures; thermodynamics and kinetics processes; synthesis of receptors; template effects.

Objective

The objective of this class is to reach an understanding of the nature and magnitude of the intermolecular interactions and solvation effects that provide the driv association between molecules and/or ions induced by non-covalent bonding interactions. The lecture (2 h) is complemented by a problem solving class (1 h) w receptor syntheses and other synthetic aspects of supramolecular chemistry.

Content

Principles of molecular recognition: cation complexation, anion complexation, cation and anion complexation in technological applications, complexation of n aqueous solution, non-covalent interactions involving aromatic rings, hydrogen bonding, molecular sef-assembly - a chemical approach towards nanostructures and kinetics of complexation processes, synthesis of receptors, template effects. Printed lecture notes will be available for purchase at the beginning of the class. Problem sets and answer keys will be available on-line.

Lecture notes

Literature Prerequisites / Notice Semester Lecturers Periodicity Language of instruction

No compulsory textbooks. Literature for further reading will be presented during the class and cited in the lecture notes. Course prerequisite: classes in organic and physical chemistry of the first two years of studies. Spring Semester 2013 A. D. Schlter yearly course English

529-0941-00L Introduction to Macromolecular Chemistry

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Abstract Objective Content

Basic definitions, types of polyreactions, constitution of homo- and copolymers, networks, configurative and conformative aspects, contour length, coi mobility, glass temperature, rubber elasticity, molecular weight distribution, energetics of and examples for polyreactions.

Understanding the significance of molecular size, constitution, configuration and conformation of synthetic and natural macromolecules for their spec chemical properties.

This introductory course on macromolecular chemistry discusses definitions, introduces types of polyreactions, and compares chain and step-growth It also treats the constitution of polymers, homo- and copolymers, networks, configuration and conformation of polymers. Topics of interest are conto formation, the mobility in polymers, glass temperature, rubber elasticity, molecular weight distribution, energetics of polyreactions, and examples for (polyadditions, polycondensations, polymerizations). Selected polymerization mechanisms and procedures are discussed whenever appropriate throu course. Some methods of molecular weight determination are introduced. Course materials (consisting of personal notes and distributed paper copies) are sufficient for exam preparation. The course will be taught in English. Complicated expressions will also be given in German. Questions are welcome in English or German. The written be in English, answers in German are acceptable. A basic chemistry knowledge is required. PhD students who need recognized credit points are required to pass the written exam.

Lecture notes Prerequisites / Notice

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