Dr. Jian Zhao Ph.D.

Professor in Molecular Genetics Teaching Duties

General Genetics for Undergraduates Crop Metabolomics for Graduates

Research Interests

Plant secondary metabolism and metabolic engineering, lipid metabolism, Crop metabolomic, flavonoid biosynthesis and regulatory network. Soybean genetic and molecular breeding, oil and flavonoid biosynthesis in soybean atural product biosynthesis in crops and medicinal plants.

Professional Memberships

!merican Society for Plant "iology American Society for Pharmacognosy

Community services Serving as Editorial Advisory Board member for #ecent Patents on "iotechnology (by Bentham Science). Reviewer for international journals such as The Plant Journal! Plant Cell & Environment, Planta, Annals of Botany, New Phytologist, Biotechnology and Bioengineering, Applied icro!iology and Biotechnology; Plant Cell "eports# Biotechnology Progress# Phytochemistry "eviews" Process Biochemistry# "iotechnology and !pplied "iochemistry etc$

Education & Working Experience

#$ucation Ph.D. harmacognosy! "###! $nstitute of %ateria %edica! &hinese Academy of %edical Sciences. Beijing. &hina. M.%. lant Biology. "##'! &ollege of (ife Sciences! )ortheast )ormal *niversity! &hangchun! . R. &hina &.%. Biology. "##+! ,e-artment of Biology! $nner %ongolia )ormal *niversity! .uhehot! .R. &hina. 'or(ing #)periences +/"+0-resent1 .ua2hong Agricultural *niversity! &ollege of lant Science and 3echnology! )ational 4ey (aboratory of &ro- 5enetic $m-rovement! +//67+/"+1 lant Biology ,ivision! 3he Samuel Roberts )oble 8oundation! 94! +//:0+//61 &hildren;s )utrition Research &enter! Baylor &ollege of %edicine! *SA +//+0+//:1 ,e-artment of Biochemistry! 4ansas State *niversity! *SA +///0+//+1 Biochemistry! 8aculty of Agriculture! 4yushu *niversity! <a-an.

Publications:
$erdier %&, 'hao %&, 3orres0<ere2 (, Ge S, )e *', %ysore +S, ,i-on #!, Udvardi M+ ./0112 3he

%t AR %=B transcri-tion factor acts as an on0switch for -roanthocyanidin biosynthesis in Medicago truncatula. Proc Natl Acad %ci &%A 103 .42 156671551 & e*ual contribution to this +or(.
'hao %, 8ang C, Bedair %! Mohamed "edair , >elti R! Sumner (>! $van Ba?ter $! 8ang *. ./0112 Suppression of phospholipase ,9s confers an increased aluminum resistance in !rabidopsis thaliana. P:oS ;ne 6.1/2< e/=0=6. doi<10.1>51?@ournal.pone

Zhao J! .uhman ,! Shadle 5! .e @A! Sumner (>! 3ang =! ,i?on RA.( ,-..) %A3E+ mediates vacuolar seBuestration of glycosylated and malonylated flavonoids in Medicago truncatula. Plant Cell$ +C1 "'CD0"'''. Zhao J! &onnorton <%! 5uo =E! (i @! ShigaFi 3! .irschi 4,! ittman <4. ( ,--/) 8unctional studies of s-lit Arabido-sis &a+GH.G e?changers. Journal of Biological Chemistry. +6:1C:/I'0C:/6C. Zhao J! ,i?on! RA. (,--/) %A3E trans-orters facilitate vacuolar u-taFe of e-icatechin CJ090 glucoside for -roanthocyanidin biosynthesis in Medicago truncatula and Arabidopsis. Plant Cell$ +"1 +C+C0+C:/. Zhao J! ShigaFi 3! %ei .! 5uo =E! &heng ).!! .irschi 4,. ( ,--/) $nteraction between Arabido-sis &a+GH.G e?changers &A@" and &A@C. Journal of Biological Chemistry +6:1 :D/'0 :D"'. Zhao J! &heng ).! %otes &%! Blancaflor EB! %oore %! 5on2ales )! admanaban S! S2e .! >ard <%! .irschi 4,. (,--0) At&.@"C is a -lasma membrane 4G trans-orter. Plant Physiology ":61I#D0 6/I. %ishra 5! Ahang >! ,eng 8! Zhao J! >ang @ (,--1) A bifurcating -athway directs abscisic acid effects on stomatal closure and o-ening in Arabido-sis. %cience C"+1+D:0+DD. Zhao J! %atsimaga =! 8ujita 4! SaFai 4. (,--1) %etabolic flu? and signal analysis of 0thuja-licin and monoter-ene biosynthesis in elicited C. lusitanica cell culture by elicitor and methyl jasmonate. eta!olic Engineering 61":0+# Zhao J! 8ujita 4! SaFai 4. ( ,--2) 9?idative burst in -lant cell culture -rocess1 a role in -roduction of K0thuja-licin by Cupressus lusitanica sus-ension culture. Biotechnology and Bioengineering #/1 D+"0DC".

Ahang >! Ein &! Zhao J! >ang @. (,--3) hos-holi-ase ,L"0derived -hos-hatidic acid interacts with AB$" -hos-hatase +& and regulates abscisic acid signaling! Proc Natl Acad %ci &%A "/"1#'/60 #'"C. Zhao J! >ang @. (,--3). 3he common -lant -hos-hol-ase ,! (,L"! interacts with Arabido-sis heterotrimeric 50-rotein L0subunit through a motif analogous to the ,R= motif in 50-rotein0cou-led rece-tors. Journal of Biological Chemistry +I#1 "I#:0"6//.
;ther Publications<

%ei .! Zhao J! ittman <4! (achmansingh <! arF S! .irschi 4,. ( ,--4) $n -lanta regulation of the Arabido-sis &a+GH.G anti-orter &A@". Journal of E'perimental Botany '61C:"#0C:+I. Zhao J. 5,--46. $nter-lay among nitric o?ide and reactive o?ygen s-ecies1 A com-le? networF determining cell survival or death. Plant %ignaling & Behavior +1'::0':I (invited Addendum to New Phytologist "I'1+"'0++#). Zhao J. 8ujita 4! SaFai 4. (,--4) Reactive o?ygen s-ecies! nitric o?ide! and their interactions -lay different roles in Cupressus lusitanica cell death and -hytoale?in -roduction. New Phytologist "I'1 +"'0++#. Buseman &%! 3amura ! S-arFs AA! Baughman E! %aatta S! Zhao J! Roth %R! Esch S>! Shah <! >illiams 3,! >elti R. (,--1) >ounding stimulates the accumulation of glyceroli-ids containing o?o-hytodienoic acid and dinor0o?o-hytodienoic acid in Arabido-sis leaves. Plant Physiology ":+1+60C#. ShigaFi 3! BarFala B! %iranda0Mergara %&! Zhao J! antoja 9! .irschi 4(,--26. $dentification of a critical histidine involved in metal trans-ort activity in Arabido-sis cationH. e?changer &A@". Journal of Biological Chemistry +6/1 C/"CD 0 C/":+ Zhao J! Aheng S.! 8ujita 4! SaFai 4. ( ,--3) <asmonate and ethylene signaling -athways and their interaction are integral -arts of the elicitor signal transduction leading to -hytoale?in biosynthesis in Cupressus lusitanica cell cultures. Journal of E'perimental Botany ''1"//C0"/"+. Zhao J! 5uo =! 8ujita 4! SaFai 4. (,--3) $nvolvement of cA% signaling in elicitor0induced -hytoale?in accumulation in Cupressus lusitanica cell cultures. New Phytologist "D"1I+C0ICC. Zhao J! SaFai 4. (,--7) %ulti-le signaling -athways mediate fungal elicitor7induced 0thuja-licin accumulation in Cupressus lusitanica cell cultures. Journal of E'perimental Botany ':1D:I0D'D. Zhao J! SaFai 4. (,--7) ero?idases are involved in biosynthesis and metabolism of 0thuja-licin in fungal elicitor0treated Cupressus lusitanica sus-ension cultures. New Phytologist "'#1I"#0IC". Zhao J! 8ujita 4! =amada <! SaFai 4. ( ,--.) $m-roved 0thuja-licin -roduction in Cupressus lusitanica sus-ension cultures by fungal elicitor and methyl jasmonate. Applied icro!iology and Biotechnology ''1 C/"0C/'. Zhao J! .u E! 5uo =E! Ahu >.. ( ,--.) Effects of stress factors! bioregulators and -recursors on indole alFaloid -roduction in the com-act callus clusters culture of Catharanthus roseus. Applied icro!iology and Biotechnology ''1 D#C0D#6. Zhao J! .u E! 5uo =E! Ahu >.. (,--.) Elicitor0induced indole alFaloid biosynthesis in &atharanthus roseus cell cultures is related to &a+G0influ? and the o?idative burst. Plant %cience

"D"1:+C0:C". Zhao J! .u E! Ahu >.. (,--.) Enhanced catharanthine -roduction in Catharanthus roseus cell cultures by combined elicitor treatment in shaFe flasFs and bioreactors. En(yme and icro!ial Technology +61DIC0D6". Zhao J! .u E! 5uo =E! Ahu >.. ( ,--.) Effects of stress factors! bioregulators and -recursors on indole alFaloid -roduction in the com-act callus clusters culture of Catharanthus roseus. Applied icro!iology and Biotechnology ''1 D#C0D#6. Zhao J! .u E! 5uo =E! Ahu >.. (,--.) Elicitor0induced indole alFaloid biosynthesis in &atharanthus roseus cell cultures is related to &a+G0influ? and the o?idative burst. Plant %cience "D"1:+C0:C". Zhao J! .u E! Ahu >.. (,--.) Enhanced catharanthine -roduction in Catharanthus roseus cell cultures by combined elicitor treatment in shaFe flasFs and bioreactors. En(yme and icro!ial Technology +61DIC0D6". Revie+ 8rticles Zhao J! ,i?on RA (,-.-) 3he NinsO and NoutsO of flavonoid trans-ort. Trends in Plant %cience. "'1I+06/. Zhao J! ang =A! ,i?on RA (,-.-) The mysteries of proanthocyanidin transport and polymerization. Plant Physiology "'C1 :CI0::C Zhao J. 5,--46 )utraceutical! nutritional thera-y! -hytonutrients! and -hytothera-y for im-rovement of human health1 A -ers-ective on -lant biotechnology a--lication. "ecent Patents on Biotechnology "1I'0#I (invited review). Zhao J 5,--46 lant tro-onoids1 &hemistry! biological activity! and biosynthesis . Current edicinal Chemistry ":(+:)1+'#I0+D+". Zhao J! Mer-oorte R. (,--4) %ani-ulating indole alFaloid -roduction in Catharanthus roseus cell cultures in bioreactors1 from biochemical -rocessing to metabolic engineering. Phytochemistry "eviews D1:C'0:'I ($nvited review)
'hao %, ,avis :C, $erpoorte # ./0042 Alicitor signal transduction leading to production of plant secondary metabolites. "iotechnology !dvances /></=>7>>>.

&oo( chapters Zhao J! SaFai 4. (,--.) $nvolvement of -ero?idases and hydrogen -ero?ide in the metabolism of 0 thuja-licin in fungal elicitor0treated Cupressus lusitanica sus-ension cultures. $n1 %orohoshi )! 4omamine A! (eds)! %olecular Breeding of >oody lants1 roceedings of the $nternational >ood Biotechnology Sym-osium. Progress in Biotechnology! Mol "6! Elsevier1 3oFyo! -+DC0+I+. Zhao J. 5,--16 Elicitor signal transduction leading to biosynthesis of -lant defensive secondary metabolites. $n1 3ei?eira da Silva < (eds)! 9loriculture! :rnamental an$ Plant &iotechnology . Mol C. 5lobal Science BooFs (td1 3oFyo! (ondon. -C::0C'I. Zhao J. 5,-..6 hytonutrient and -hytothera-y for im-roving health. In eter rendergast and %elvin A. Shiffman (eds)! 8esthetic Me$icine 8rt an$ Techni*ues. S-ringer0Merlag 1 .eidelberg! 5ermany! art +! -:I0'6. Zhao J. 5,-.,6 )utraceuticalsHfunctional foods for im-roving health and -reventing disease. $n1 9liver 4ayser and .eribert >ar2echa (eds)! Pharmaceutical &iotechnology ;Drug Discovery an$

Clinical 8pplications 5,n$ #$ition6. >iley0M&. Merlag1 >einheim! 5ermany. -'##0D+6.

Patent
Merdier <A! Zhao J! ,i?on RA! *dvardi %4. %ethods and &om-ositions for Regulating roducing roanthocyanidins. ending a--lication to *SA -atent office.

Contact details
%ian 'hao Ph.,. Professor of Molecular Genetics ational +ey :aboratory of Crop Genetic (mprovement College of Plant Science and Bechnology )uaChong !gricultural University 1 ShiCishan, )ongshan ,istrict 8uhan, China D>0054 Bel< E=67/57=5>=4133 Amail< @ianChaoFmail.hCau.edu.cn