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Retinoic acid acts by binding to the retinoic acid receptor (RAR) with the retinoid X receptor (RXR) in regions called retinoic acid response elements (RAREs). Binding of the retinoic acid ligand to RAR alters the confirmation of the RAR, which affects the binding of other proteins that either cause or suppress transcription of a nearby gene (molecular unit of heredity). Transcription is the first step in gene expression, which is the process by which information from a gene is used to produce a protein, like collagen. Retinoic acid receptors mediate transcription of different sets of genes controlling differentiation of a variety of cell types, thus the target genes regulated depend upon the target cells. In some cells, one of the target genes is the gene for the retinoic acid receptor itself, which amplifies the response. Control of retinoic acid levels is maintained by a suite of proteins that control synthesis and degradation of retinoic acid. Therefore, retinoids improve the way the skin sheds and renews itself by binding to and activating these RARs.
Conclusion
Aging is a natural process that occurs in everyone, but keeping the skin looking younger is becoming an increasing aspiration. Decreasing skin cells and collagen levels give a wrinkled and translucent appearance that is not desirable. Natural derivatives of vitamin A, called retinoids, can help make the desire of younger looking skin a reality by working on the molecular level within skin cells. They help to speed up cell turnover and stimulate collagen production, giving skin the smoother and firmer appearance associated with younger looking skin.
References
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699641/ http://www.doctoroz.com/videos/anti-aging-why-retinols-work http://www.skinacea.com/retinoids/what-are-retinoids.html#.Uy9us_ldXo4 http://www.vivo.colostate.edu/hbooks/pathphys/misc_topics/vitamina.html