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DARIEN NICETY A. SASAN BSN III-B (o, kang nice jud ni. Kai loser ko.

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Mechanism of
Drug Data Classification Indication Contraindications Adverse Reaction Nursing Responsibilities
Action

Generic Name: Therapeutic: » Inhibits » Oral, IV: Edema» Contraindicated » CNS: dizziness, vertigo, Before:
Furosemide anti-infective reabsorption of associated with in patients with paresthesias, xanthopsia, » Ask if patient has allergy to furosemide and
sodium and heart failure, allergy to weakness, headache, drowsiness, sulfonamides.
Trade name: Pharmacologic- chloride from the cirrhosis, renalfurosemide, fatigue, blurred vision, tinnitus, » Assess if pt. has SLE, gout and diabetes
Lasix, Loop Diuretic proximal and distal disease sulfonamides; irreversible hearing loss mellitus.
Apo-Furosemide tubules and allergy » Arrange to monitor serum electrolytes
Furosemide Special Pregnancy ascending limb of » IV: Acute » severe renal » CV: orthostatic hypotension, hydration, liver and renal functions.
Risk Category:C the loop of Henle, pulmonary edema failure volume depletion, cardiac » Arrange for potassium-rich diet or
Content: leading to a » hepatic coma arrythmias, thrombophlebitis supplemental potassium as needed.
Furosemide sodium-rich » Oral: » pregnancy » Observe 15 cardinal rights in giving
diuresis. Hypertension » lactation medication.
» Dermatologic:
Maximum Dosage:
Photosensitivity, rash, pruritus,
120 mg Pharmacokinetics » Precaution During:
urticaria, purpura, exfoliative
- with SLE » Administer with food or milk to prevent GI
dermatitis, erythema multiforme
Minimum Dosage: M: hepatic - gout upset.
10mg/ml D: crosses - diabetes mellitus » Reduce dosage with other antihypertensives,
»GI: vomiting, nausea, anorexia,
placenta, enters readjust dosage gradually as BP responds.
oral and gastric irritation,
Availability: breast milk » Give early in the day so that increased
constipation, diarrhea, acute
Tablets: 20, 40, 80 E: feces, urine urination will not disturb sleep.
pancreatic, jaundice
mg; Oral Solution: » Avoid IV use if oral use is possible.
10mg/mL, Half-Life: 30-60min » Do not mix parenteral solution with highly
» GU: polyuria, nocturia,
40mg/5mL; acidic solutions with pH below 3.5
glycosuria, urinary blader spasm
Injection: 10mg/mL Route: Oral; IV, IM
Onset: 60min; 5min After:
» HEMA: leukopenia, anemia,
Route: Oral, IM, IV Peak: 60-120min; - Discard diluted solution after 24hrs..
thrombocytopenia, fluid and
30min Refrigerate oral solution.
electrolyte imbalances,
Duration: 6-8hr; » Measure and record weight to monitor fluid
hyperglycemia, hyperuricemia
2hr changes.
» Report loss or gain of more than 3 pounds in 1
» Other: muscle cramps and
day.
muscle spasms
» Do not expose to light, which may discolour
tablet or solution.

Source: Nursing Drug Source: Nursing Source: Nursing Drug Source: Nursing Drug Source: Nursing Drug Source: Nursing Drug Handbook, 2009. Source: Nursing Drug Handbook, 2009. Lippincott
Handbook, 2009. Drug Handbook, Handbook, 2009. Handbook, 2009. Handbook, 2009. Lippincott Williams and Wilkins, Williams and Wilkins, Philadelphia. Pages 552
Lippincott Williams and 2009. Lippincott Lippincott Williams Lippincott Williams Lippincott Williams Philadelphia. Pages 551-552
Wilkins, Philadelphia. Williams and and Wilkins, and Wilkins, and Wilkins,
Pages 563-565 Wilkins, Philadelphia. Pages Philadelphia. Pages Philadelphia. Pages
Philadelphia. p551 551 551 551

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