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VISION

A premier university in historic Cavite


recognized for excellence in the development
of morally upright and globally competitive
individuals.



Republic of the Philippines
CAVITE STATE UNIVERSITY
Don Severino Delas Alas Campus
Indang, Cavite
MISSION
Cavite State University shall provide excellent, equitable
and relevant educational opportunities in the arts, science
and technology through quality instruction and relevant
research and development activities. It shall produce
professional, skilled and morally upright individuals for
global competitiveness.



Drug Mechanism of
Action
Indication Contraindication Side effects Nursing
responsibilities
Generic:
Paracetamol ,
Acetaminophen


Brand: Biogesic,
Panadol, Tylenol

Classification:
Non-narcotic
analgesic,
Antipyretic

Dosage: 500-1,000
mg

Route: Oral, IV

Frequency: 4-6 hrs



Form:


- Decreases fever
by a hypothalamic
effect leading to
sweating and
vasodilation
-Inhibits pyrogen
effect on the
hypothalamic-
heat-regulating
centers
-Inhibits CNS
prostaglandin
synthesis with
minimal effects on
peripheral
prostaglandin
synthesis
-Does not cause
ulceration of the
GI tract and causes
no anticoagulant
Symptomatic treatment
of mild to
moderate pain &/or fever.
-Nephrotoxicity.
-Renal Insufficiency
-Anemia

Occasionally, skin rashes
& hypersensitivity
reactions. Renal damage
(long-term use).
Hematological reactions
including
thrombocytopenia,
leukopenia &
methemoglobinemia
resulting to cyanosis.
Minimal GI upset.
1. Methemoglobinemia
2. Hemolytic Anemia
3. Neutropenia
4. Thrombocytopenia
5. Pancytopenia
6. Leukopenia
7. Urticaria
8. CNS stimulation
9. Hypoglycemic coma
10. Jaundice

1. Do not exceed
4gm/24hr. in adults
and 75mg/kg/day in
children.
2. Do not take for
>5days for pain in
children, 10 days
for pain in adults,
or more than 3 days
for fever in adults.
3. Extended-Release
tablets are not to
be chewed.
4. Monitor CBC, liver
and renal functions.
5. Assess for fecal
occult blood and
nephritis.
6. Avoid using OTC
drugs with
Acetaminophen.
7. Take with food or
milk to minimize GI
upset.
8. Report N&V.
Color: Brown

action.

11. Glissitis
12. Drowsiness
13. Liver Damage

cyanosis, shortness
of breath and
abdominal pain as
these are signs of
toxicity.
9. Report paleness,
weakness and
heart beat skips
10. Report abdominal
pain, jaundice, dark
urine, itchiness or
clay-colored stools.
11. Phenmacetin may
cause urine to
become dark
brown or wine-
colored.
12. Report pain that
persists for more
than 3-5 days
13. Avoid alcohol.
14. This drug is not for
regular use with
any form of liver
disease.









Drug Mechanism of Action Indication Contraindication Side effects Nursing responsibilities
Generic:
Paracetamol

Brand: Aeknil


Classification:
Analgesic (Opiod)

Dosage: 2-3 ml

Route: IV

Frequency: Q4

Form:


Color:
Paracetamol produces
analgesia by raising
the threshold of the
pain center in the brain
n by obstructing
impulses at the pain-
mediating
chemoreceptors. The
drug produces
antipyretics by an
action on the
hypothalamus; heat
dissipation is increased
as a result of
vasodilation an
increased peripheral
blood flow.

-pyrexia of
unknown
origin,fever and
pain associated
with common
childhood
disorders
,tonsillitis, upper
respiratory tract
infection post
immunization
reactions.
-Prevention of
febrile convulsion,
headache, cold,
sinusitis,musle
pain,arthritis and
toothache.


-Liver damage
-skin rashes
-blood disorders and
swollen pancreas.

-Use liquid form of children and
patients who have difficulty
swallowing.
-In children, dont exceed five dose in
24 hrs
-Advise patient that drug is only for
short term use and to consult the
physician if giving to children for
longer than 5 days.
- Advise patient that many over the
counter products contains
acetaminophen; be aware of this
when calculating total daily dose.
-Warn patient that high doses or
unsupervised long term can cause
liver damage.

DRUG NAME

INDICATIONS

ACTION
CANTRAINDICATIONS &
CAUTIONS
NURSING
RESPNSIBILITIES

Generic Name:
Cefuroxime Axetil
Cefuroxime Sodium

Brand Name:
(Ceftin[P.O])
(Zinacef [Parenteral])


*Pharyngitis, tonsillitis, infections of
the urinary and lower respiratory
tracts, and skin and skin- structure
infections

*Serious lower respiratory tract
infections,UTIs,skin and skin-
structure infections, bone and joint
infections,septicemia,meningitits
and gonorrhea

*uncomplicated UTIs

*otitis media

*perioperative prevention

*Early Lyme disease (erythema
migrans)

*Secondary bacterial infection f
acute bronchitis

*Uncomplicated gonorrhea

*Acute bacterial maxillary sinusitis


Second-generation
cephalosporin that
inhibits cell-wall
synthesis,promoting
smtic instability;usually
bactericidal

ADVERSE ACTION:
CV: phlebitis,
thrombophlebitis
GI: pseudomembranous
colitis, nausea, anorexia,
vomiting, diarrhea
HEMATOLOGIC:
Transient neutropenia,
eosinophilia, hemolytic
anemia,
thrombocytopenia
SKIN:
Maculopapular and
erythematous rashes,
urticaria, pain,
induration, sterile
bscesses, temperature
elevation, tissue

*Contraindicated in patient
hypersensitive to drug

*use cautiously in patients
hypersensitive to penicillin
because of possibility of
cross-sensitivity with other
betalactam antibiotics

*Use with caution in breast
feeding women and in
patients with history of
colitis or renal sufficiency.

*Before administering,
make sure patient is not
allergic to penicillins r
cephalosporins.

*Absorption of cefuroxime
axetil is enhanced by food.

*Cefuroxime axetil tblets
may be crushed if
swallowing is a difficult.

*Cefurxime axetil tablets
may be dissolved in small
amounts of apple,orange,
or grape juice, even
chocolate milk.

*High fat meals increased
drug bioavailability.

*ALERT. Cefuroime axetil
film-coated tblet and oral
suspension are not
bioequivalent.

*ALERT. Do not confuse
with other cephalosporins
that sound like.

sloughing at
intramuscular injection
site
OTHER:
Hypersensitivity
reactions, serum
sickness,anaphylais

*Take medicine as
prescribed,even after
feeling better.

*Take oral form with food
.
*If suspension is being
used, shake the container
well before measuring
dose.

*Notify prescriber about
rashes or super infections.

*Notify prescriber about
loose stools or diarrhea.