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Nucleic Acid

Discovered by Friedrich Miescher



Considered as informational polymers that are
essential for life

Polymeric macromolecules or biological
molecules

Nucleic Acid
Nucleotide
Monomer
Made up of 3 components:
Codon: a group of three nucleotides

Phosphate group
Nitrogenous base
Pentose/ 5-carbon sugar
Two Types of Nucleic Acid
1. DNA
(Deoxyribose Nucleic Acid)
Provides direction for
replication
Control protein
synthesis & direct RNA
synthesis
Genetic material
inherited from parent
Two Types of Nucleic Acid
2. RNA
(Ribonucleic Acid)
Involved in the
replication of DNA
Forms messenger RNA
(mRNA)

Cell
[Latin] cella. little boxes
Robert Hooke
first to observe and describe cells in cork and leaf

Matthias Jakob Schleiden
Cell Theory: all organisms are composed of cells

Theodore Schwann
Similarity and difference of animal cells and plant
cells

Cell Characteristics
Metabolism
Cells can independently take and convert energy
as well as eliminate wastes
Reproduction
Asexual or sexual reproduction to produce
daughter cells
Responsiveness
Ability to adapt to external and internal stimuli


Cell Characteristics
Cell Surface Membrane
Lipid bilayer to filter incoming and outgoing
substances
Plant cells: also has additional layer of cell wall

Functionally Independent Structures
Organelles
Specialized parts of the cells enabling cell processes
Can be bound in a membrane of their own
Organizational Cell Types
Types:
1. Prokaryotic
Oldest living organisms
No complex with histone proteins
Structured simply
2. Eukaryotic
With membrane-bound organelles
Has different regions: cell membrane,
cytoplasm and nucleus
Parts of Eukaryotic Cell
Cell membrane plasma membrane
Boundary of cells
Serves as protective layer; semi-permeable
Regulator of flow of materials in and out of cells
Parts of Eukaryotic Cell
Cytoplasm
Cytosol: gel-like portion inside the cell where most
metabolic reactions occur
Subparts:
1. Mitochondria
Powerhouse of the cell
2. Golgi apparatus
Packaging and transport of macromolecules to designated
organelles
3. Centrioles
Determinant for cell division orientation
Parts of Eukaryotic Cell
4. Endoplasmic Reticulum
For metabolic purposed
Rough ER: flat; protein synthesis
Smooth ER: tubular; lipid metabolism
5. Lysosomes
Intracellular digestion
6. Microbodies
Degradative enzymes for cell cleaning
7. Cytoskeleton
Provides structure and movement
Microfilaments, intermediate filaments, microtubules
Parts of Eukaryotic Cell
8. Ribosomes
Protein synthesis
9. Cilia, Flagella
locomotion
10.Vacuoles
Waste management, storage
11.*Plastids*
Chloroplast: photosynthetic
Chromoplast: pigmentation
Amyloplast: storage
Leucoplast: non-pigmented
Parts of Eukaryotic Cell
Consists of two membranes
Nuclear envelope serves as opening for cell
communication
Nucleoli carrier of multiple DNA information
Storage of DNA
Ribosomal RNA combines with proteins after
DNA transcription to form ribosome and move
to cytoplasm

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